Phase 3 N=7,808 A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis
Osteoporosis
Primary: Number of Participants With New Vertebral Fractures — 264; 86 Participants — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=30 Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients
Healthy Subjects · Renal Impairments
Primary: Maximum Observed Plasma Concentration (Cmax) of Ucb L059 (LEV) for Groups A to D — 21.9357; 15.5334; 10.7767; 9.1754 µg/mL
N/A N=40 Can a Nasal Decongestant Test Predict Treatment Outcomes in Seasonal Allergic Rhinitis?
Seasonal Allergic Rhinitis
Primary: Global Assessment — 1.7; 1.4 units on a scale — p=0.372
N/A N=224 A Prospective Randomized Study for Comparison of Y-Composite Grafts
Coronary Artery Disease
Primary: 1 Year Graft Patency Rates — 97.1; 97.1 percentage of distal anastomoses
N/A N=30 The Pharmacokinetics of Azithromycin Prophylaxis for Cesarean Delivery
Endometritis
Primary: Number of Patients in Each Group That Attain an Adequate Azithromycin Concentration — 0; 0; 0 number of participants
N/A N=33 Intraoperative Bleeding During Endoscopic Sinus Surgery
Blood Loss
Primary: Estimated Blood Loss — 78.5; 80.3 mL/h — p=0.937
Phase 3 N=676 A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea
Diabetes Mellitus, Type 2
Primary: Change in Glycosylated Hemoglobin (HbA1c) From Baseline to Week 18 — -0.47; -0.97; -1.06 Percent — p=<0.001
Phase 2 N=12 Phase II Study of Combination of Paclitaxel Poliglumex and Alimta for Advanced Non-small Cell Lung Cancer (NSCLC)
Advanced Non-small Cell Lung Cancer
Primary: To Evaluate the Overall Response Rate (Complete Plus Partial Responses by RECIST Criteria) to the Combination of Paclitaxel Poliglumex and Pemetrexed as Therapy in…
Phase 4 N=122 Performance Study of Newly Developed Ostomy Products
Stoma Colostomy
Primary: Degree of Leakage. Each Baseplate Can Have a Score From 0-24 Points Were 0 is the Best Possible Outcome (No Leakage) and 24 Points is the Worst Possible Outcome (Full…
Phase 2 N=40 Effects of Transcranial Direct Current Stimulation on the Apathy of Alzheimer's Disease
Apathy · Alzheimer's Disease
Primary: Apathy Symptoms — -2.05; -1.95 units on a scale — p=0.55
N/A N=82 Imaging Predictors of Treatment Response in Depression
Major Depressive Disorder
Primary: Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks — 12; 12 participants
Phase 3 N=624 Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated Influenza
Influenza
Primary: Time to Resolution of All Clinical Symptoms of Influenza as Reported by the Subjects — 109.1; 116.7; 95.5 Hours
Phase 1 N=32 A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo)
Herpes Simplex Virus · Neonatal Sepsis
Primary: Clearance (CL) — 0.278 L/h/kg
Phase 2 N=50 Abraxane and Avastin as Therapy for Patients With Malignant Melanoma, a Phase II Study
Metastatic Malignant Melanoma
Primary: Progression-free Survival (PFS) at 4 Months — 75 percentage of patients
Phase 3 N=157 Zinc for the Treatment of Herpes Simplex Labialis (HSL)
Herpes Simplex Labialis
Primary: Zicam Was Compared to Placebo as a Treatment of Recurrent HSL From the Date and Time of the Initiation of Therapy Until the Date and Time of Resolution of the Lesion or…