65,437 trials
Alzheimer Disease · Dementia
Primary: PWMC Loneliness — 4.90; 5.28 units on a scale
Uveitis · JIA
Primary: Time to Treatment Failure — NA; 119 Time to treatment failure (days) — p=<0.0001
HIV Infections
Primary: Number of Solicited Local Events Post Vaccination 1 by Priming Dose Group (Outcome 1) — 23; 27; 25; 10 Participants
Acute Respiratory Distress Syndrome · Coronavirus Infection
Primary: Number of Participants Who Are Classified 8 (Dead), 7 (Hospitalized, on Invasive Mechanical Ventilation or ECMO), or 6 (Hospitalized, on Non-invasive Ventilation or High…
Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Primary: Change From Baseline in Facial Pain/Pressure/Fullness on NRS at 2 Hours Post-Dose — -2.70; -2.61 Scores on a scale — p=0.7782
COPD
Primary: Change From Baseline in 1-hour Morning Post Forced Expiratory Volume in 1 Second (FEV1) — 0.248; 0.156; 0.138; -0.050 Litres — p=<0.001
Multiple Sclerosis · Colitis, Ulcerative
Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — 8; 3; 2; 6 Participants
Transgender Health · Gender Dysphoria · Transgender Women
Primary: Doravirine Area Under the Plasma Concentration Versus Time Curve From 0 Hours to Infinity (AUC0-∞) — 17798.14; 18413.21 hr*ng/mL
NASH - Nonalcoholic Steatohepatitis
Primary: Change in Liver Stiffness on Magnetic Resonance Elastography (MRE) — 0.025; -0.265; 0.105; 0.135 Change in kPA
Gastrointestinal Neoplasms · Cholangiocarcinoma · Pancreatic Neoplasms
Primary: Maximum Tolerated Dose (MTD) of BI 905711 in Phase 1a — NA milligram / kilogram (mg/kg)
Tuberculosis
Primary: Assess Viable BCG Bacteria From Intradermal Challenge Site From Culture. — 20,440; 80; 5; 10,673 CFU
Overweight and Obesity · PreDiabetes · Type 2 Diabetes
Primary: Change in BMI — 0.43; 0; 4.4; 0 kg/m2 — p=0.2
Pregnancy Complications
Primary: Plasma Concentration Troponin I — 1.2; 1.2 ng/L — p=0.05
Prolonged Grief Symptoms
Primary: Prolonged Grief Scale — 34; 21; 24; 26 points
Lipoprotein Disorder
Primary: Percent Change From Baseline in Lp(a) - Assessed Via Intact Lp(a) Assay — -47.35; -81.57; -85.71; 0.48 Percent change — p=<.001