65,437 trials
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With Adverse Events (AE), Serious Adverse Events (SAE) and Adverse Events of Special Interest (AESIs) — 35; 1; 0 Participants
Dyssynergic Defaecation · Evacuation Disorder · Anismus
Primary: The Rate of Identification of Puborectalis During Ultrasound Scan — 8 Participants
Non Small Cell Lung Cancer · Lung Cancer Stage III
Primary: 12-Month Progression-free Survival (PFS) Time — 208 days
Multiple Osteochondroma · Ollier Disease · Osteogenesis Imperfecta
Primary: Health-related Quality of Life — 0.91; 84 score on a scale
Liver Diseases · Hepatic Impairment
Primary: Plasma Maximum Concentration (Cmax) of Sisunatovir Following Administration of a Single Oral Dose — 81.25; 68.52; 73.85; 127.8 Nanograms/milliliter (ng/mL)
Obesity
Primary: Body Weight Change — -12.99 kg — p=<0.0001
Cutaneous Lupus
Primary: Change in Percentage of UVB-induced Apoptotic Epidermal Cells — 20.06; 3.03; -17.03 percentage of epidermal cells
Healthy
Primary: Change From Baseline in Cardiorespiratory Fitness at 12 Weeks — -0.6; -1.0 ml/kg/min
Gingivitis
Primary: Adjusted Mean Change From Baseline in the Number of Bleeding Sites (NBS) at Week 12 — -14.6 bleeding sites — p=<0.0001
EPP · XLP
Primary: Change From Baseline in Average Daily Sunlight Exposure Time (Minutes) to First Prodromal Symptom (Burning, Tingling, Itching, or Stinging) Associated With Sunlight…
Postmenopausal Women With Osteoporosis
Primary: Efficacy: Percentage Change From Baseline (%CfB) in Lumbar Spine Bone Mineral Density (LS-BMD) at 52 Weeks - Modified Full Analysis Set (mFAS) — 5.86; 5.66 Percentage…
Healthy
Primary: Pharmacokinetics(PK): Area Under the Plasma Concentration Versus Time Curve From Zero to Infinity (AUC[0-∞]) of Selpercatinib — 23400; 22500 nanogram * hour per…
Alzheimer Disease · Dementia · Dementia, Vascular
Primary: Constructive Engagement Mean on Menorah Park Engagement Scale — 1.22 score on a scale — p=<.01
Hemostasis · General Surgery
Primary: To Evaluate the Safety of sFilm-FS Versus an Active-comparator (TACHOSIL®) When Used as Adjunct to Conventional Hemostatic Techniques During Elective Surgery Through…
Autism · Autism Spectrum Disorder · Autistic Disorder
Primary: Reduction in Social Responsiveness Scale, Second Edition (SRS-2) - Adult (Relative/Other Report) — 68.67; 70.41; 66.08; 72.33 Scaled Score — p=.006