17,261 trials
Chronic Plaque Psoriasis
Primary: Change From Baseline in Psoriasis Area and Severity Index (PASI) at Week 28 — -10.76; -19.74 scores on a scale
Nonalcoholic Fatty Liver Disease (NAFLD)
Primary: Percent Change in Alanine Aminotransferase (ALT) Level — 11.99; -7.99 percentage change
OCD
Primary: CY-BOCS Total Score at 12-weeks — 14.1; 0 units on a scale
Autism Spectrum Disorders
Primary: Change in Aberrant Behavior Checklist-Modified Social Withdrawal Subscale ABC-mSW, a Measure of Social Reciprocity — 8.81; 8.68; 8.97; 8.68 score on a scale — p=0.503
Anterior Cruciate Ligament Reconstruction
Primary: Cross-sectional Area of Skeletal Muscle Fibers (All Fibers) — 2827; 3318; 2206; 2376 micrometer squared — p=<0.05
Age-related Macular Degeneration
Primary: Ocular Safety as Assessed Using Biomicroscopy to Investigate Ocular Tolerability — 0; 0; 1 Participants
Cancer
Primary: Number of Participants Receiving Treatment or Retreatment Who Experience a Treatment-Emergent Adverse Event (TEAE)
BRAF or NRAS Mutant Metastatic Melanoma
Primary: Percentage of Participants With Objective Response (OR) — 4.9; 14.5; 12.0 percentage of participants
Root Caries
Primary: Root Caries Activity — 3.72; 40.52 Percentage of active lesions (2-years)
Neovascularization, Choroidal · Macular Degeneration, Age-Related
Primary: Mean Change From Baseline in Best Corrected Visual Acuity (BCVA) at Week 40, Using the Early Treatment Diabetic Retinopathy Study (ETDRS) BCVA Charts — 9.3; 12.5; 11.4…
Epilepsy · Seizures
Primary: Number of Participants With Serious Adverse Events (SAEs) — 0; 1; 2 Participants
Skin Basal Cell Carcinoma
Primary: Overall Response Rate — 69.7 percentage of tumor lesions
Erectile Dysfunction · Overactive Bladder · Urinary Incontinence
Primary: Erectile Function Assessed by IIEF Questionnaire — 12.7 score on a scale
Docosohexaenoic Acid Supplementation of Mothers to
Primary: Infant Serum Soluble Receptor for AGE (sRAGE) Levels at 4 Weeks From Baseline From Mothers Supplemented With 200 or 1000 mg/kg Per Day of DHA — 900; 1127 pg/mL
Systemic Lupus Erythematosus
Primary: Dose of Triptorelin for Ovarian Suppression — NA; 120 μg/kg