65,437 trials
Dry Eye Syndrome · Tear Film Insufficiency
Primary: Change From Baseline (V2) in Frequency and Severity of Dry Eye Symptoms (SANDE) Questionnaire Scores at Day 28±4 (End of Treatment) — -11.9; -16.6; -25.0; -26.5 mm
Anorexia Nervosa · Atypical Anorexia Nervosa
Primary: Criticism — 5.5; 3.7; 3.7; 4.3 score on a scale
Cardiovascular Diseases
Primary: Flow Mediated Dilation — 7.07; 7.25 percent point change in arterial diamete
Covid19
Primary: Composite Outcome of Symptomatic Deep Vein Thrombosis, Pulmonary Embolism, Other Venous Thromboembolism, Ischemic Stroke, Myocardial Infarction, Other Arterial…
Nasolabial Folds
Primary: Change in Modified Fitzpatrick Wrinkle Scale (MFWS) From Day 0 to Day 180 — -1.309 score on a scale
Depression, Postpartum · Anxiety
Primary: Treatment Effect on Mother-infant Bonding — 99.33; 99.35; 101.11; 97.90 score on a scale — p=0.5
Proximal Humeral Fracture · Proximal Tibia Fractures · Diaphyseal Fracture
Primary: Performance: Fracture Healing — 29; 26; 2; 0 Fractures
Alcohol Use Disorder · Anxiety Disorders
Primary: Mean Number of Drinks Consumed Per Week — 40.82; 29.62; 12.12; 23.86 Standard Drinking Units per Week — p=0.002
Rectal Cancer
Primary: Clinical Complete Response (cCR) — 0.24 Proportion of Participants
Depressive Disorder, Major
Primary: Mean Blood Oxygenation Level Depend (BOLD) Signal % Change in an Emotional Paradigm, Based on the Emotional Faces From the Warsaw Set of Emotional Facial Expression…
Chronic Migraine · Chronic Migraine, Headache · Chronic Migraine Without Aura
Primary: Mean Change in the Number of Monthly Migraine Headache Days — -8.17; -7.78; -5.77 number of days
Hypertension
Primary: Change in Seated Diastolic Blood Pressure Between AZM and Placebo — 3.9; -1.6 mmHg
Generalized Lipodystrophy
Primary: Absolute Change From Baseline in Participants With Elevated Baseline Hemoglobin A1c (HbA1c ≥7%) at Week 8 — -0.1; 0.2 millimoles per mole (mmol/mol)
Healthy Participants
Primary: Maximum Observed Plasma Concentration (Cmax) of Intact AMG 133 — 12.3; 22.7; 44.9; 22.5 μg/mL
Inflammation
Primary: Loneliness — 47.9; 46.9; 46.8; 44.6 score on a scale