N/A N=57 Intra-articular Polyacrylamide Hydrogel in the Treatment of Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in the Total WOMAC Score (WOMAC-T) — 1137.13; 767.47; 1271.60; 445.33 score on a scale — p=0.00
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=13 Revitalize Cognition: Near Infrared Stimulation in Older Adults
Aging
Primary: NIH Examiner Battery, Executive Composite Changes From Baseline to Post-testing — 0.33; 0.22 z-score — p=.575
Phase 2 N=80 Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum
HIV Infections
Primary: Estimated Threshold of Maternal Steady-state Tenofovir Diphosphate (TFV-DP) Concentration Levels Corresponding to Optimal Adherence in the PK Component — 965; 1050…
N/A N=237 i-Matter: Investigating an mHealth Texting Tool for Embedding Patient-reported Data Into Diabetes Management
Type2 Diabetes
Primary: HbA1c Level at Baseline — 8.37; 8.29 Percentage of total hemoglobin
Phase 2 N=27 Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
Gastric Adenocarcinoma · Esophagogastric Junction · Gastric Cancer
Primary: Overall Survival (OS) — 11.96 Months
N/A N=739 CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy
Polyps · Adenoma Colon · Colorectal Polyp
Primary: To Evaluate Whether Using the CADDIE System Improves Endoscopist Detection of Adenomas During Colonoscopy. — 33.30; 25.20 ADR (% of participants)
Phase 3 N=248 A Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung Cancer
ALK+ Advanced NSCLC
Primary: Progression-free Survival (PFS) as Assessed by Blinded Independent Review Committee (BIRC) Per RECIST v1.1 — 19.253; 19.187 months — p==0.8672
N/A N=78 Family Palliative and End-of-Life Care for Advanced Heart Failure
Heart Failure NYHA Class III · Heart Failure NYHA Class IV
Primary: Patient Heart Failure Health Status (KCCQ)- Baseline — 26.79; 27.11 score on a scale
Phase 1 N=13 A Study to Find the Best Dose of BI 905711 in Combination With Chemotherapy and to Test Whether This Dose Helps People With Advanced Gastrointestinal Cancers
Gastrointestinal Cancer, Metastatic
Primary: Determination of the Maximum Tolerated Dose (MTD) of BI 905711 — NA milligram / kilogram (mg/kg)
Phase 1 N=13 INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
Glioblastoma Multiforme · Anaplastic Astrocytoma · Anaplastic Oligodendroglioma
Primary: Number of Patients Who Experienced Dose-limiting Toxicities (DLTs) — 3 Participants
N/A N=359 Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications
Chronic Pain · Depression, Anxiety · Opioid Use
Primary: 6-month Change in PROMIS Pain Interference — -2.13; -2.66 T-score — p=.57
N/A N=47 Dietary Nitrate and Muscle Power With Aging
Aging · Sarcopenia
Primary: Maximal Knee Extension Velocity — 12.2; 12.7 radians per second
N/A N=120 App-based Remote Blood Pressure Monitoring
Gestational Hypertension · Preeclampsia · Chronic Hypertension Complicating Pregnancy
Primary: Blood Pressure Ascertainment — 40; 39 Participants
Phase 2 N=44 Ph II Study of Pembrolizumab & Eribulin in Patients With HR+/HER2- MBC Previously Treated With Anthracyclines & Taxanes
Breast Cancer
Primary: Efficacy of Pembrolizumab in Combination With Eribulin. — 25 Participants
N/A N=17 Effect of a Basic Skin Care Product on the Structural Strength of the Skin
Healthy Skin
Primary: Blistering Time (Full Blister) — 63; 54; 65; 62 Minutes