Phase 3 N=30 Cholecalciferol Supplementation for Sepsis in the ICU
Hypovitaminosis D
Primary: Change in Vitamin D Status 5 Days Following Supplementation With Cholecalciferol — 19; 15; 17; 19 ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=219 Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis
Psoriatic Arthritis
Primary: Percentage of Participants Who Achieved an American College of Rheumatology 20% (ACR20) Response at Week 16 — 20.2; 38.2 percentage of participants — p=0.0040
Phase 3 N=173 Effect of Aspirin Pretreatment or Slow Dose Titration on Flushing and Gastrointestinal Events in Healthy Volunteers Receiving Delayed-release Dimethyl Fumarate
Healthy
Primary: Percentage of Participants Reporting Overall Flushing Events During the Overall Treatment Period, as Assessed by the Modified Flushing Severity Scale (MFSS) — 41; 91…
Phase 3 N=1,021 A Study of the Addition of Avastin (Bevacizumab) to Carboplatin and Paclitaxel Therapy in Patients With Ovarian Cancer
Ovarian Cancer
Primary: Percentage of Participants With at Least One Adverse Event (AE) — 97.8 percentage of participants
Phase 3 N=265 Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Vitamin D Deficiency · Pregnancy
Primary: 25-hydroxyvitamin D at Visit 7 — 36.7; 39.8 ng/mL
Phase 3 N=58 A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)
Hypercholesterolemia
Primary: Total Cholesterol Concentration of Chylomicron (Sf≥400) Fractions After a Cholesterol-Rich Test Meal — 0.45; 0.50 mg/dL — p=0.241
Phase 3 N=224 Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCTN0401)
Lymphoma, B-Cell · Lymphoma, Large-Cell, Immunoblastic · Lymphoma, Non-Hodgkin
Primary: Progression-free Survival (PFS) — 53.2; 56.6; 48.6; 49.0 percentage of participants
Phase 3 N=62 Treatment Strategy for Alcohol Use Disorders in Veterans With TBI
Alcohol Dependence
Primary: Time to Relapse to Heavy Drinking as Defined by Having 5 or More Drinks in a Sitting for Men and Will be Assessed Using the Time Line Follow Back for Recent Drinking…
Phase 3 N=53 Long-term Safety of SPD422 in Japanese Adults With Essential Thrombocythaemia
Essential Thrombocythemia (ET)
Primary: Change From Baseline in Platelet Count at Final Assessment — 1021.6; -346.2 10^9 platelets per liter (10^9/L)
Phase 3 N=614 A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative Colitis
Ulcerative Colitis
Primary: Percentage of Participants With Remission at Week 8 — 18.5; 8.2 percentage of participants — p=0.0070
Phase 3 N=457 Efficacy Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Patients
Type 1 Diabetes
Primary: Change From Baseline in Glucagon-stimulated C-peptide AUC at 24 Months — -3.848; -4.348 nmol*minute/L — p=0.2851
Phase 3 N=374 Comparative Study to Evaluate Efficacy and Safety When Metformin Hydrochloride 500 mg Once Daily is Added on to SYR-322 25 mg in Type 2 Diabetic Patients With Inadequate Glycemic Control Despite Treatment With SYR-322 25 mg in Addition to Diet and Exercise Therapy
Type 2 Diabetes Mellitus
Primary: Change From Baseline in Glycosylated Hemoglobin A1c (HbA1c) National Glycohemoglobin Standardization Program (NGSP) at the End of Treatment (EOT) Period — 0.16; -0.49…
Phase 3 N=315 A Study to Evaluate the Efficacy and Safety of Reslizumab (0.3 or 3.0 mg/kg) as Treatment for Patients (12-75 Years of Age) With Eosinophilic Asthma
Eosinophilic Asthma
Primary: Change From Baseline In Forced Expiratory Volume In 1 Second (FEV1) Over 16 Weeks Using Mixed Model for Repeated Measures — 0.126; 0.242; 0.286 liters — p=0.0018
Phase 3 N=54 Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae
End Stage Renal Disease · AV Fistula · Kidney Failure
Primary: Use of Venous Window Needle Guide to Obtain Arteriovenous Access for Hemodialysis — 49 participants
Phase 3 N=460 Establishing the Vitamin D Requirements During Lactation
Vitamin D Deficiency
Primary: 25-Hydroxyvitamin D Levels for Postpartum Mother 7 Months After Delivery — 28.5; 38.0; 55.6 ng/mL