Phase 1 N=24 A Phase 1 Study of EXT608 in Healthy Adults
Safety Issues
Primary: Characterize the Safety and Tolerability of EXT608 — 2; 2; 0; 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=270 Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Dermatological Non-Disease
Primary: Responder Status Based on Independent Evaluating Investigator Live Assessment at Week 24 - Full Analysis Dataset — 222; 221 Participants — p=<0.0001
N/A N=103 Gamification-Augmented Home-Based Exercise for Peripheral Artery Disease
Peripheral Artery Disease
Primary: Change in Daily Step Count — 783; 1770 steps per day
Phase 4 N=20 Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis
Erectile Dysfunction
Primary: Visual-analogue Pain Scale — 6; 4 units on a scale
Phase 2 N=698 A Study of mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1 Candidate Seasonal Influenza Vaccines in Healthy Adults
Seasonal Influenza
Primary: Number of Participants With Solicited Local and Systemic Adverse Reactions (ARs) — 77; 86; 81; 72 Participants
N/A N=51 Painted Playgrounds Aim 1
Childhood Obesity
Primary: Change in Children's Physical Activity Levels During Recess — 2.3; 4.3; 3.5; 0.5 count of participants
N/A N=38 Improving Locomotor Learning With Brain Stimulation
Motor Learning
Primary: Prefrontal Cortical Activity — 0.04; 0.11; 0.58; -0.62 μM
Phase 2 N=20 Neoadjuvant Atezolizumab in Surgically Resectable Advanced Cutaneous Squamous Cell Carcinoma
Cutaneous Squamous Cell Carcinoma
Primary: Percentage of Patients Who Complete Neoadjuvant Therapy and Were Eligible for Curative Surgical Resection — 16 Participants
N/A N=150 Intensive Models of HCV Care for Injection Drug Users
Hepatitis C · Medication Adherence
Primary: Electronically Monitored Medication Adherence — 86; 80; 75 Percentage of medication taken
N/A N=25 Nicotine Pharmacokinetic Study of Heated Tobacco and Heated Herbal Products
Healthy Volunteers
Primary: Nicotine Cmax — 13.00; 12.97; 6.00; 6.87 ng/mL
N/A N=394 McGrath Videolaryngoscopy and Direct Laryngoscopy Rapid Sequence Intubation
Surgery
Primary: Visualization of the Vocal Cords — 90; 85; 63; 67 Participants — p=0.26
Phase 2 N=1,079 A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age
Cervical Intraepithelial Neoplasia
Primary: Number of Participants Reporting Grade 3 Solicited Administration Site Events After Vaccine Dose 1 — 11; 12; 6; 2 Participants
N/A N=60 The ShortCut™ Study Protocol
Risk of Coronary Obstruction Following Transcatheter Aortic Valve Replacement (TAVR) Procedure
Primary: (Number of Patients With) ShortCut™ Device- and/or ShortCut™ Procedure-related Mortality and All Cause Stroke — 0; 1; 59 Participants
Phase 3 N=51 Daily vs. Every Other Day Oral Iron Supplementation in Patients With Absolute Iron Deficiency Anemia
Anemia · Iron Deficiency Anemia
Primary: Feasibility of Enrolling Patients in the Trial — 85 participants
Phase 3 N=1,733 Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy
Transthyretin (TTR) Amyloid Cardiomyopathy
Primary: Time to All-Cause Mortality: Cohort A — 58.7; 35.8 Months — p=0.0001