12,372 trials
Spondylitis, Ankylosing
Primary: Time-Weighted Average Change From Baseline in the Spinal Pain Intensity in Study Part 1: Etoricoxib 90 mg vs. Naproxen — -31.23; -30.59 mm VAS
Depression · Bipolar Disorder
Primary: Hamilton Rating Scale for Depression Scores — 3.50; 7.25 units on a scale
Avascular Necrosis of Femoral Head
Primary: Number of Participants With Femoral Head Collapse Within 24 Months — 29; 22 participants
Rheumatoid Arthritis
Primary: Pharmacokinetic (PK) Analysis: Adjusted Geometric Mean Observed Serum Trough Concentration at Steady State (Cminss) of Abatacept Using a Prefilled Syringe (Measured on…
Breast Cancer
Primary: Percentage of Participants With Second-Line Progression-Free Survival (PFS) According to Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1 (v1.1) — 88.7…
Seasonal Allergic Rhinitis
Primary: Primary Efficacy — -3.83; -2.77 units on a scale
Chronic Heart Failure
Primary: Primary Composite Endpoint: First Event Among Cardiovascular Death (Including Death of Unknown Cause) or Hospitalization for Worsening Heart Failure. — 793; 937…
Clinical Pharmacology
Primary: AUC (0-72): Area Under the Plasma Concentration-time Curve From Time 0 to 72 Hours Postdose for Unchanged SYR-322 (SYR-322Z) — 1494.9; 1472.8 nanogram*milliliter per…
Myopia
Primary: Percentage of Eyes With Loss of More Than 2 Lines Best Spectacle Corrected Visual Acuity (BSCVA) — 0 percentage of eyes
Cardiac Transplant · Patent Ductus Arterious · Atrial Septal Defect
Primary: Changes in Hemodynamic Variables Recorded During Administration of Sevoflurane + Dexmedetomidine. — -0.14; -0.16; -0.21; 0.15 percentage of change from baseline — p=0.05
Chronic HCV Infection
Primary: Percentage of Participants With Sustained Virologic Response (SVR) at 12 Weeks After Discontinuation of Therapy (SVR12), Treatment-naive, Noncirrhotic Participants…
Coronary Disease · Ventricular Dysfunction, Left
Primary: Primary Composite Endpoint — 844; 832 participants — p=0.945
Coronary Artery Disease
Primary: Primary Composite Endpoint — 654; 611 participants — p=0.1969
Growth Hormone Deficiency
Primary: Change From Baseline in Height Standard Deviation Score (SDS) for Chronological Age (CA) at Month 36: Full Analysis Population — -2.91; 0.80 Standard Deviation Score…
Opioid-Related Disorders · Opiate Dependence
Primary: Retention in Treatment in the Per Protocol Population — 113; 122 participants — p=<0.05