N/A N=2,367 Reducing CNS-Active Medications to Prevent Falls and Injuries in Older Adults
Aging · Accidental Fall
Primary: Medically Treated Falls — 328; 349 Participants — p=0.11
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=14 Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis
ALS
Primary: Dose Limiting Toxicities (DLT) — 1; 2 Participants
Phase 1 N=100 A Study of Soticlestat in Healthy Adult Nondependent Recreational Drug Users With Central Nervous System (CNS) Depressant Experience
Healthy Volunteers
Primary: Treatment Phase: Drug Liking (Maximum Effect [Emax]) "At This Moment" as Assessed Using Bipolar Visual Analogue Scale (VAS) — 56.7; 57.3; 56.5; 88.5 score on a scale
N/A N=53 Natural History Study in Subjects With Usher Syndrome
Usher Syndrome, Type 1B
Primary: BCVA - Better Seeing Eyes — -2.26 ETDRS score — p=<0.01
N/A N=44 Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor
Hematologic Malignancy
Primary: Proportion of Patients Undergoing an Allo HCT Transplant Who Have a KIR Favorable Donor. — 23; 21 Participants
Phase 3 N=1,353 A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Chronic Plaque Psoriasis · Moderate to Severe Chronic Plaque Psoriasis
Primary: Number of Treatment Emergent Adverse Events (TEAEs) Adjusted by Duration of Subject Exposure to Investigational Medicinal Product (IMP) — 97.83; 179.68; 79.02; 77.11 no…
N/A N=77 Clinical Evaluation of the CM-1500 During Apheresis Blood Donation
Fluid Loss
Primary: Characterize Changes in the Relative Index During an Apheresis Procedure — 94.9; 99.3 Relative Index
N/A N=27 Reasoning Training in Individuals With Bipolar Disorder
Bipolar Disorder · Cognitive Ability, General
Primary: Change From Baseline: Test of Strategic Learning — 2.35; 3.04 score on a scale — p=0.040
N/A N=264 The Rate of Successful Intubation and the Required Time for Intubation, Using Vie Scope and Macintosh Laryngoscope Will be Compared, in Order to Evaluate the Efficacy of Vie Scope in Comparison With Macintosh in Expected Easy Airways.
Laryngoscopy
Primary: Rate of Successful Intubation With One Attempt — 132; 119 Participants — p=0.0002
N/A N=330 Evaluation of Point-of-Care (EPOC) for COVID-19
COVID-19 · SARS CoV 2 Infection
Primary: Test Results Comparison Between LumiraDx and GenScript — 0.097 Unitless
Phase 1 N=43 A Study to Investigate the Effects of Sisunatovir on QTc Interval in Healthy Adult Participants.
Healthy
Primary: Placebo-Adjusted Change From Baseline in QT Interval Corrected Using Fridericia's Formula (QTcF) at Expected Maximum Concentration (Cmax) on Day 3 for Sisunatovir…
N/A N=60 Effect of Fibre Supplements on Gestational Diabetes
Gestational Diabetes
Primary: Numbers Diagnosed With Gestational Diabetes — 7; 6 Participants — p=0.639
N/A N=10 Time to Eat Study - Pilot
Overweight
Primary: Number of Participants With Treatment-Emergent Adverse Events as a Measure of Safety and Tolerability — 3 Participants
N/A N=105 Effect of Use of DryNites Absorbent Pants on the Rate of Spontaneous Resolution of Paediatric Nocturnal Enuresis (NE)
Nocturnal Enuresis
Primary: Wet Nights — 2.4; 4.6 wet nights per week
N/A N=38 Kidney Transplant Low-AGE Diet Study
Renal Transplant
Primary: Skin Autofluorescence (SAF) Levels at 6 Months — 2.8; 2.8 Arbitrary units