65,437 trials
Elevated Blood Pressure
Primary: Muscle Sympathetic Nerve Activity — -2; -1 bursts per minute — p=0.51
Rhinosinusitis Chronic · Microbiome
Primary: Comparaison of Alpha-diversity of Sino-nasal Microbiota Before and After Treatment (Visit 1 and Visit 2) — 2.041; 2.114 Shannon Index — p=0.908
Rib Fractures · Trauma
Primary: Pain Level — 1.79; 2.85 score on a scale
Peripheral Arterial Disease
Primary: Primary Efficacy Endpoint: Freedom From MALE — 144 Participants
Oncology
Primary: System Usability Scale (SUS) — 82 score on SUS
Autism Spectrum Disorder · Depression · Suicidal Ideation
Primary: Change in Severity of Adolescent Depressive Symptoms, Self-report — 8.14 T-score
Amputation; Traumatic, Hand
Primary: VAL-1: System Comfort Validation Test — 100 % of participants who Passed test
Chronic Pain · Problematic Opioid Use
Primary: Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Behavior — 66.7; 66.0; 64.3; 66.8 units on a scale
Exercise-Induced Laryngeal Obstruction
Primary: Percentage of Participants With Continuous Laryngoscopy During Exercise Tests — 100 percentage of participants
COVID-19 Vaccination
Primary: Receipt of Any Dose COVID-19 Vaccination — 57621; 65407 Participants — p=0.202
Acute Graft Versus Host Disease
Primary: Phase I: Measurement of Pharmacokinetic (PK) Parameter, AUClast, in aGvHD and SR-aGvHD Patients — 252; 372; 154; 239 ng*hr/mL
Resectable Soft Tissue Sarcoma · Soft Tissue Sarcoma
Primary: Maximum Tolerated Dose (MTD) / Recommended Phase 2 Dosage for Each Cohort — 5; NA times per week of 125mg PO
COPD
Primary: Change in Chronic Respiratory Disease Questionnaire (CRQ)- Dyspnea Score — 0.68; 0.71; 0.34; 0.83 score on a scale
Cardiac Arrhythmia
Primary: Rate of Acute Success Based on Pre-defined Procedural Endpoints — 901 Participants
Unresectable Non-small Cell Lung Cancer (NSCLC)
Primary: Number and Proportion of Participants With Adverse Events (AEs), Serious Adverse Events (SAEs), and AEs of Special Interest (AESI) — 74; 21; 74; 21 Participants