65,437 trials
Smoking · Tobacco Use
Primary: Mean Cigarettes Per Day — 13.1; 12.6; 12.2; 13.3 cigarettes per day
Recurrent Lung Non-Small Cell Carcinoma · Stage IV Non-Small Cell Lung Cancer AJCC v7
Primary: Progression-free Survival (PFS) — 14.2; 4.4 Months
PTSD · Depression · Chronic Pain
Primary: Columbia Suicide Scale — 1.19; 1.09 score on a scale
Melanoma
Primary: Objective Response Rate (ORR) in the Full Analysis Set Analysis Population — 45.0 Percentage of participants
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome · Adult Acute Myeloid Leukemia in Remission · Blasts Under 10 Percent of Bone Marrow Nucleated Cells
Primary: Recurrence-free Survival Rate — 8.5 Months
Adenomatous Polyposis Coli
Primary: Change in Marked Polyp Size — 16; 4; 0 Size of marked polyps
Liver Transplant; Complications · NAFLD
Primary: Number of Participants With Adverse Events Assessed by CTCAE — 12 Participants
Congenital Adrenal Hyperplasia
Primary: Safety and Tolerability - Number of Participants With Adrenal Insufficiency — 25; 41 Participants
Pneumococcal Disease
Primary: Percentage of Participants With Local Reactions Within 7 Days After Vaccination — 1.0; 1.0; 0.0; 0.5 Percentage of participants
Alcohol Use Disorder (AUD) · Substance Use Disorders
Primary: Change in Number of Substance Use Occasions — -11.3; -11.2; -13.6; -12.9 occasions
Non-Alcoholic Fatty Liver Disease · Nonalcoholic Steatohepatitis
Primary: Percentage Change From Baseline in Serum Alanine Aminotransferase (ALT) Levels at Week 16 — -26.2; -27.0; -44.9; 2.6 Percentage change — p=0.0002
Pancreatic Adenocarcinoma · Pancreatic Ductal Adenocarcinoma · Pancreatic Intraductal Papillary-Mucinous Neoplasm
Primary: Overall Survival (Percentage of Participants Alive) [Phase II] — 29.9; 28.1 months — p=0.62
Asthma in Children
Primary: Hospital Admission — 57; 208 Participants
Postmenopausal Osteoporosis
Primary: Percentage Change From Baseline (%CfB) in Lumbar Spine Bone Mineral Density (BMD) — 5.68; 5.19 Percentage change from baseline
Resected Pancreatic Adenocarcinoma
Primary: Incidence of Dose Limiting Toxicites (DLTs) — 0; 1 Dose limiting Toxicities