65,437 trials
Vascular Diseases · Peripheral Arterial Disease · Hemodialysis Access Failure (Disorder)
Primary: Incidence of Central Neurologic Events — 2 Participants
Metastatic Melanoma · Stage IV Cutaneous Melanoma AJCC v6 and v7
Primary: CTL With Anti-CTLA4
Placenta Praevia · Vaginismus
Primary: Caesarean Delivery — 79 Participants
Chronic Hepatitis B
Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs) — 5; 4; 5; 4 Participants
Abdominal Trauma
Primary: Sensitivity of Detecting Solid Organ Injury Measured as the Number of True Positives — 18; 20 Participants
PTSD
Primary: CAPS-5 — 41.6; 20.8 score on a scale
Prurigo Nodularis
Primary: Time From Baseline to Relapse Meeting At Least 1 of the Defined Criteria — NA; 112.50 Days
Sickle Cell Disease
Primary: Percentage of Group C Participants Who Achieved Complete Resolution of Vaso-occlusive Events (VOE-CR) — 87.5 percentage of participants
Thumb Osteoarthritis
Primary: Change in Pain Post-operatively Using the Visual Analog Scale (Pain VAS) — 2.5; 4.2; 5.3; 5.8 score on a scale — p=0.135
Alopecia Areata
Primary: Area Under the Plasma Concentration-Time Profile Over the Dosing Interval of 24 Hours, at Steady State (AUC24ss/AUCtau) of Ritlecitinib on Day 7 — 437.5 Nanogram*hours…
Atrial Fibrillation · Cardioversion · Cerebrovascular Stroke
Primary: Combined Clinical Thromboembolic or Hemorrhagic Event, Death or Silent Cerebral Thromboemboli — 9; 11 Participants
Thymic Carcinoma · Non-small Cell Lung Cancer · Refractory Thoracic Tumors
Primary: Recommended Phase II Combination Dose in Phase I (Per Common Terminology Criteria for Adverse Events (CTCAE) Criteria Version 5) — 200 mg
Coronavirus
Primary: Deterioration Resulting in Healthcare Review — 10 alerts generated
Hepatocellular Carcinoma · Hepatoma · Liver Cancer, Adult
Primary: Objective Response Rate(ORR) Assessed by BICR — 13.3; 10.5; 12.5 Percentage
Alzheimer Disease
Primary: Change From Baseline in Florbetapir Positron Emission Tomography (PET) Scan Standard Uptake Value Ratio (SUVr) — -0.050; -0.122; -0.183; -0.255 standard uptake value…