17,261 trials
Cognitive/Functional Effects · Metastatic Cancer · Unspecified Adult Solid Tumor, Protocol Specific
Primary: Percent Change in Delayed Recall at 4 Months as Measured by the Hopkins Verbal Learning Test-Revised (HVLT-R) — 7.0 percent change — p=<0.001
Carpal Tunnel Syndrome
Primary: Change From Baseline Levine Symptom Severity Scale Status at Weeks 6, 12,18. — 0.4; -3.2; -4.2; -9.4 Scores on a scale
Peanut Hypersensitivity
Primary: The Percentage of Subjects Who Pass the 20gm Peanut Flour (~50% Peanut Protein) Oral Food Challenge 2-4 Weeks After Discontinuing Peanut OIT Therapy — 3; 1 Participants
Atrial Fibrillation
Primary: Exposure-adjusted Incidence Rate of Major or Clinically Relevant Non-major Bleeding Episode — 2.02; 10.1; 10.5; 14.6 Number of Patients per 100 Patient years — p=0.035
Adult Primary Hepatocellular Carcinoma · Advanced Adult Primary Liver Cancer · Localized Unresectable Adult Primary Liver Cancer
Primary: Dose-limiting Toxicities (DLT) and Maximum Tolerated Dose (MTD) of Belinostat in Patients With Inoperable HCC (Phase I) — 0; 0; 0; 1 Participants
Soft Tissue Sarcoma
Primary: Maximum Tolerated Dose (MTD) Measured of TH-302 When Used in Combination With Doxorubicin and Prophylactic Growth Factor Support in Subjects With Advanced Soft Tissue…
Healthy
Primary: Age-Dependent Change in Striatal 18F-DTBZ Uptake of Healthy Subjects. — 0.05 SUVR
Fragile X Syndrome
Primary: Change in Mullen Scales of Early Learning - Expressive Language Raw Score — 19.3; 21.3; 21.3; 25.04 units on a scale
Acute Myocardial Infarction
Primary: Ischemia Area at Risk as Determined by Paired Single-photon Computed Tomography Studies With Technetium Tc99m Sestamibi.
Huntington's Disease
Primary: Tolerability as Assessed by Ability to Complete the Study on the Originally Randomized Treatment Assignment. — 90.0; 93.1; 81.3 percentage of participants
Multiple System Atrophy, MSA
Primary: Striatum Brain Region: Change From Baseline in Microglia Activation Via Positron Emission Tomography(PET) — -0.23; 0.12; -0.35 ml/cc — p=0.13
Infections, Bacterial
Primary: Number of Participants With Composite of the Cure Rate as Measured by Clinical Response and Outcome at the Early Efficacy Visit Combined With Withdrawal Rate — 48; 28…
Alzheimer's Disease · Vascular Dementia · Dementia
Primary: Word List Memory Total - ADAS-cog — 14.35; 14.7; 15.1; 14.67 Words recalled
Dyslipidaemias · Dyslipidemias
Primary: The GSK256073 Area Under Concentration-time Curve (AUC) and High Density Lipoprotein Cholesterol (HDLc) Data to Evolve the Exposure-response…
Venous Thrombosis
Primary: Number of Subjects With Major and Clinically Relevant Non-Major Bleeding Events — 0; 0; 0; 0 Participants