65,437 trials
Endometriosis
Primary: Reduction of Dysmenorrhea (DYS) at Month 3 - Proportion of Responders — 44.0; 72.9; 23.5 Percentage of responders — p=<0.001
Healthy
Primary: Heart Rate Accuracy of Masimo INVSENSOR00057 — 1.38 bpm
Mild Cognitive Impairment · Insomnia
Primary: Sleep Latency — 28.51; 47.06 minutes
Advanced Adult Hepatocellular Carcinoma · Child-Pugh Class A · Stage III Hepatocellular Carcinoma
Primary: Overall Response Rate Defined as Partial or Complete Response Per Immune-related Response Evaluation Criteria in Solid Tumors — 8; 19 Participants
Advanced Stage Non-small Cell Lung Cancer
Primary: Best Overall Response Rate (Confirmed Partial + Complete Response) Will be Assessed as Part of This Study. Tumor Response Will be Assessed Using RECIST 1.1) — 7; 5; 5…
Non-alcoholic Steatohepatitis
Primary: Percentage of Participants With At Least One Stage of Liver Fibrosis Improvement With No Worsening of Non-Alcoholic Steatohepatitis (NASH) After 48 Weeks — 10.6; 29.2…
Presbyopia
Primary: Mean Change From Baseline in Binocular Distance Corrected Near Visual Acuity (DCNVA) — 4.1; 4.3; 4.4 EDTRS letters
Healthy
Primary: Percentage (%) of Subjects With Drug-related Adverse Events (AEs) — 13.3; 9.1; 36.4; 57.9 Percentage of Participants
Type 2 Diabetes
Primary: Maximal Exercise Capacity (VO2max) — 20.7; 20.0; 27.6; 21.9 mL/kg/min
Convalescent Plasma · COVID-19 · SARS-CoV 2
Primary: Duration of Oxygenation Support — 7.4 days
Cataract
Primary: Percentage of Participants Who Experienced at Least One Intraocular Pressure (IOP) Measurement ≥30 Millimeters of Mercury (mmHg) at Any Post-Surgical Follow-up Visit…
Major Depression
Primary: Depression Remission — 130; 126 Participants
Normal Physiology
Primary: The Standardized Uptake Value Ratio (SUVR) for [11C]Raclopride in Putamen — 4.49; 4.39; 4.87 SUV Ratio (SUVR)
Depressive Symptoms · Anxiety Generalized
Primary: Health-related Quality of Life (HRQoL), RAND 36-Item Health Survey Changed Value (Baseline to 2 Months) — -0.89; -1.85 score on a scale
Type2 Diabetes · Depression
Primary: Change in HbA1c — 0.06; -0.03; -0.17; 0.20 percentage of glycosylated hemoglobin