Phase 1 N=80 CC-42344 Safety Study in Healthy Participants
Influenza A
Primary: Part 1 SAD: Number of Participants With Treatment-Emergent Adverse Events (TEAE) — 3; 3; 6; 4 Participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=67 INRT-AIR: A Prospective Phase II Study of Involved Nodal Radiation Therapy
Head and Neck Squamous Cell Carcinoma
Primary: Risk of Solitary Elective Volume Recurrence Following Elective Volume Reduction Using INRT — 11; 9; 3; 6 percentage of participants
N/A N=20 The Psychophysiological Effect of Simulated and Terrestrial Altitude
Hypoxia · Altitude Hypoxia · Altitude Sickness
Primary: Oxygenation of the Brain — 54.6; 54.3; 59.4; 55.4 percentage of oxygen saturation
Phase 2 N=87 Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies
Hematologic Malignancies
Primary: Number of Participants Who Have Severe Acute Graft-versus-host-disease (GVHD) — 2; 0; 5; 1 Participants
N/A N=161 Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease
Dry Eye Disease
Primary: Change From Baseline in Impact of Dry Eye on Everyday Life - Symptom Bother (IDEEL-SB) Questionnaire Score at Day 30 — -16.95 score on a scale — p=<.0001
N/A N=4,115 NUCALA® Special Drug Use Investigation (EGPA, Long-term)
Churg-Strauss Syndrome · Eosinophilic Granulomatosis With Polyangiitis
Primary: Number of Participants With Adverse Drug Reactions (ADRs) — 57 Participants
N/A N=12 Acute Intermittent Hypoxia in Traumatic Brain Injury
Brain Injuries, Traumatic
Primary: Change in Vitals at Visit 2 — 0 Participants
Phase 2 N=91 Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate
Prostate Cancer
Primary: Number of Participants With Grade 2 or Greater GU and GI Toxicity — 9; 2; 1; 1 Participants
N/A N=15 Stone Access and Removal (STAR) Study
Kidney Calculi
Primary: Percentage of Participants Who Achieved Successful Completion of Robotic-Assisted Combined Intrarenal Surgery (RACIRS) Kidney Stone Removal Procedure — 100; 100; 100…
N/A N=40 A Clinical Comparison of Two Soft Toric Contact Lenses
Astigmatism
Primary: Subjective Overall Score — 76.5; 75.5 units on a scale
Phase 2 N=33 Discovery of Sirolimus Sensitive Biomarkers in Blood
Lymphangioleiomyomatosis
Primary: Number of Sirolimus-Sensitive Plasma Protein Biomarkers in Lymphangioleiomyomatosis (LAM) Participants — 662 plasma proteins
Phase 3 N=20 Switch Over Study of Biosimilar Agalsidase Beta for Fabry Disease
Fabry Disease
Primary: Change From Baseline in Lyso Gb3 Serum Levels — 4.99; 5.12; 4.95; 5.14 Nmol/L
N/A N=100 Effect of Peer Support Intervention on Medication Adherence, Self-care and Knowledge Among Patients With Diabetes
Peer Influence · Medication Adherence · Self Care
Primary: Medication Adherence Status — 29; 39; 18; 8 Participants
Phase 4 N=52 A Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft (ActiveMatrix) Verses Standard of Care in Adhesive Capsulitis of the Shoulder
Adhesive Capsulitis
Primary: Change in Pain as Assessed by the Shoulder Pain and Disability Index (SPADI) — -37.8; -9.5 score on a scale
Phase 3 N=309 A Study to Assess Adverse Events and Change in Disease Activity of Intramuscular AGN-151586 Injection in Toxin-Naïve Adult Participants With Glabellar Lines
Glabellar Lines
Primary: Percentage of Participants With a Grade 0 or 1 and a ≥ 2-grade Improvement From Baseline on the FWS According to Both Investigator and Subject Assessments of Glabellar…