Clinical Trial Search

Primary: Cutaneous Tolerance Scores: Erythema — -0.07 Units on a scale

Primary: The Primary Endpoint of This Study is the Percent of Patients Who Achieved Clear (0) or Almost Clear (1) on IGA Scale at Week 16 — 78 percentage of participants — p=<0.008

Primary: Number of Participants Satisfied and Very Satisfied With Regimen — 42 participants

Primary: Mean Change From Baseline in Total Lesion Count — -26.9 Lesions counted

Primary: Change From Baseline in Corneometer Values at 8 Hours on Day 1 — 6.14; 2.63; 3.60 Arbitrary Corneometer unit — p=0.0128

Primary: Proportion of Patients With Moderate to Severe Hypopigmentation and Hyperpigmentation Assessed After Treatment — 0; 0 participants

Primary: Number of Inflammatory Lesions (Papules and Pustules) — 6; 3; 10; 0 Lesions

Primary: Level of IL-1β — 52.5; 361.2 pg/mg

Primary: Mean Percent Change in Inflammatory Lesion (IL), Non-inflammatory Lesion (NIL), and Total Lesion (TL) Counts From Baseline (BL) (Day 1) to Week (Wk) 8. — -55.93; -52.64…

Primary: Mean Percent Change in Inflammatory, Non Inflammatory, and Total Lesion Counts From Baseline to Week 8 — -62.1; -49.8; -56.9 Percent change

Primary: PGA Score — 0.53 score on a scale

Primary: Reduction of Undesirable Effects — 26; 38; 35; 10 participants — p=0.001

Primary: Global Acne Grading System Score — 32; 30.33; 21.67; 27.5 score on a scale

Primary: Total Lesion Count — 76.7; 53.9; 50.0; 43.7 lesions

Primary: Subject 's Overall Satisfaction With Study Treatment Via a Satisfaction Questionnaire — 36 Participants

Primary: Mean Change From Baseline to Week 12 in Global Acne Assessment Score (GAAS) — -0.86 score on a scale

Primary: Mean Percent Change From Baseline in the Papules and Pustules Lesion Count — 68.18; 63.56; 50.72 percentage of lesion change

Primary: Number of Participants With Successful Engraftment of Probiotic Following a Single Application. — 2; 1 Participants

Primary: CLR-transformed Abundance of Any Significant Taxa — 3.29; -2.49; -1.59; -2.75 Relative Abundance

Primary: Change From Baseline in the Global Assessment of Acne Severity (GAAS) Score by Physician — 2.8; -1.2 score on a scale

Primary: Number of Correct Responses to Questionnaire Items Immediately Before and After and Educational Lecture — 79; 79; 74; 79 participants

Primary: Mean Percent Change in Inflammatory, Non-inflammatory and Total Lesion Counts From Baseline to Week 8. — -78.70; -61.52; -69.32; -77.09 Percent change — p=0.0769

Primary: Percentage Change in Inflammatory Lesions From Baseline to End of Treatment — -20.3; -29.4 percentage of change

Primary: Photoactive Porphyrins Level — 33.0; 24.8; 19.7 Fluorescence intensity unit

Primary: Percent Change From Baseline to Week 12 in the Inflammatory (Papules and Pustules) Lesion Counts on the Face — -60.84; -62.17 percentage change in lesion counts — p=0.5947

Primary: Change From Baseline (Log10 Cfu/cm²) in Count of Follicular P. Acnes — -1.94; -1.56 Log10 cfu/cm²

Primary: Subject Reported Change From Baseline Scale — 0; 0; 7; 6 Participants

Primary: Mean Percent Changes in Inflammatory (IL), Non-inflammatory (NIL), and Total Lesion (TL) Counts From Baseline to Each Study Visit — -30.4; -44.8; -52.9; -59.8 Percent…

Primary: Global Face Total Lesion Count - Percent Change - Baseline to Week 12 — -42.64; -47.80 Percent Change in Lesions — p=0.538

Primary: Physician Global Assessment — 2.65; 2.6; 2.55; 2.45 units on a scale