Phase 2 N=100 Oral Azithromycin Versus Doxycycline in Posterior Blepharitis
Posterior Blepharitis
Primary: Change of Blepharitis Symptoms Score — 1.8; 2.8 score — p=0.03
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=558 Comparative Study to Evaluate ISV-305 Compared to Vehicle in Blepharitis Subjects
Active, Symptomatic Blepharitis
Primary: Number of Participants in the ITT Population With a Reduction in the Day 1 (Baseline) Total Clinical Signs and Symptom Score by at Least 2 Units at Day 15 With No…
Phase 2 N=129 Evaluation of AXR-270 for the Treatment of Posterior Blepharitis Associated With Meibomian Gland Dysfunction
Posterior Blepharitis · Meibomian Gland Dysfunction
Primary: Adverse Events — 1; 1; 2; 0 adverse events
Phase 3 N=412 Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis
Blepharitis
Primary: The Proportion of Participants Cured Based on Their Collarette Score of 0 for the Upper Eyelid. — 0.547; 0.122 Proportion cured
Phase 3 N=421 Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis
Blepharitis
Primary: Proportion of Participants Cured Based on a Collarette Score at Day 43. — 0.439; 0.072 Proportion cured
Phase 4 N=30 Comparative Study in the Efficacy of Topical Besifloxocin With Erythromycin for the Management of Acute Blepharitis
Blepharitis
Primary: Improvement in Signs and Symptoms of Blepharitis — 15; 15 participants
Phase 2 N=36 Study Evaluating the Safety and Tolerability of NCX 4251 for the Treatment of Acute Exacerbations of Blepharitis
Blepharitis
Primary: COHORT 1 and 2 COMBINED: Mean Change From Baseline to Day 14 in the Composite (Sum) Score of Signs & Symptoms of Blepharitis — -2.0; -1.2 units on a scale — p=0.0471
Phase 2 N=75 Topical IL-1-Ra for Treatment of Posterior Blepharitis
Posterior Blepharitis
Primary: Meibomian Gland Secretion Quality — 1.7; 1.7; 1.8 Units on a scale
Phase 2 N=224 Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension for the Treatment of Blepharitis
Blepharitis
Primary: Percentage of Study Eyes With Complete Cure (Score 0) of Blepharitis Signs and Symptoms at Day 15 — 4; 2 study eyes — p=0.4434
N/A N=38 To Compare Blephapad Combo vs Standard Treatment for Eyelid Cleansing in Bilateral Posterior Blepharitis
Bilateral Blepharitis (Disorder)
Primary: Percentage Change of the Total Score of the Grading Scales for Meibomian Gland Dysfunction (MGD) — -38.5; -29.9 percentage of change in the total score
Phase 2 N=70 Treatment of Patients With Blepharitis and Facial Rosacea
Blepharitis · Meibomianitis · Dry Eye
Primary: Change in Bulbar Conjunctival Hyperemia — -0.61; -0.60 Scores on a scale — p=0.578
Phase 2 N=11 Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids
Uterine Fibroids · Uterine Leiomyomata
Primary: Treatment-related Adverse Events (AE) Per Subject Resulting From HIFU Treatment of the Uterine Fibroids — 1.3 treatment-related AE/patient
Phase 3 N=195 A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)
Primary Myelofibrosis · Post-polycythemia Vera Myelofibrosis · Post-essential Thrombocythemia Myelofibrosis
Primary: Total Symptom Score (TSS) Response Rate at Week 24 — 24.62; 9.23 Percentage of participants — p=0.0095
N/A N=169 Sleep Apnea Intervention for Cardiovascular Disease Reduction
Obstructive Sleep Apnea
Primary: Change From Baseline in 24-hour Blood Pressure at Months 6 and 12 by Pooled Arms — 1.82; 1.06; 0.59; -0.73 mmHg
N/A N=30 Active Video Games and Appetite Control in Adolescents
Active Video Games and Appetite Control
Primary: Energy Intake and Energy Expenditure (Over 24 Hours and Over 3 Days) — 17981; 17014; 17566; 10413 kJ