Clinical Trial Search

Primary: Pain Intensity — 2.8; 3.0; 2.8; 3.0 score on a scale — p=0.16

Primary: Change in Functional Disability as Measured by the Roland Morris Disability Questionnaire — 5; 4; 7 units on a scale

Primary: Lower Back Strength-Extension — 54.5; 50.2; 49.2; 57.5 kg-Force

Primary: Pain Assessed on a 10-point Numeric Pain Scale — 6.55; 6.68; 4.63; 5.13 cm

Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire — 11.1; 11.9 units on a scale

Primary: Change From Baseline in Pain on 11- Point Numerical Rating Scale at Week 7 — 1.32; 3.63 units on a scale — p=<0.001

Primary: Oswestry Disability Index — 9.8; 6.6 units on a scale

Primary: Participant-reported "Flares" of Low Back Pain (Aim 1) — 7.3 Mean flares per year

Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire — 11; 11 units on a scale

Primary: Number of Patients Who Reported Transition From Acute to Chronic Low Back Pain (cLBP) — 312; 318 Participants

Primary: Low Back Pain After 6 Weeks of Intervention — 6.50; 6.00; 1.50; 3.50 units on a scale

Primary: Visual Analogue Scale of Pain — 47.3; 45.2 units on a scale

Primary: Change From Baseline in Oswestry Disability Scale (0-100%) — -8.26; -7.75; -8.00; -9.48 units on a scale

Primary: Change From Baseline to 11 Weeks in Oswestry Disability Scale (0-100%) — -11.06; -9.10 units on a scale — p=<.0001

Primary: Change in Pain: Visual Analog Scale (VAS) — 2.1 units on a scale (centimeters)

Primary: Change From Baseline to Day 5 in Functional Impairment — 11.9; 9.4; 10.9 score on a scale

Primary: Numerical Rating Scale (0-10), an Interval Pain Scale, on Which 0 Indicates no Pain and 10 Indicates the Worst Pain Imaginable — 7.1; 5.8 units on a scale

Primary: Change From Baseline in Oswestry Disability Index — -8.8; -17.0; -17.0; -22.4 units on a scale

Primary: Pain Intensity — 4.2; 4.1; 4.0 score on a scale

Primary: Number of Particpants Screened Per Month — 103 participants per month

Primary: Intensity of Low Back Pain (LBP) Self-Estimated by Visual Analogical Scale (VAS) — 4.5; 4.2; 5.4; 3.9 milimeters

Primary: Difference in the Proportion of Primary Outcome Successes Between Treatment Groups — 27; 9 participants — p=<0.00001

Primary: Leg Length Inequality — 0.3; 0.58 centemeter

Primary: Pain Intensity Difference (PID) Between Pre-dose Baseline and 8hours After First Application — -1.049; -1.428; -2.252; -2.410 units on a scale — p=<0.0001

Primary: Change in Modified Oswestry Disability Questionnaire (0-100%) From Baseline to Completion of Initial 6 Week Intervention Phase — 32.3; 32.6; 12.8; 21.2 score on a scale

Primary: Change of Pain Intensity After 10 Days of Treatment — -5.1; -4.0 units on a scale — p=<0.001

Primary: Change in Oswestry Disability Index From Baseline to 10 Weeks — -8.8; -6.1 Units on a scale — p=0.02

Primary: Functional Impairment as Measured on the Roland Morris Disability Questionnaire — 10.9; 9.4; 8.1 units on a scale

Primary: Oswestry Disability Index — .42; .83; 10.41; .42 score on a scale

Primary: Oswestry Low Back Pain Disability Index — -16.0; -8.9; -9.5 units on a scale — p=0.009