Phase 4 N=180 IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Abdominal Wall Hernia · Pancreatic Diseases · Bowel Disease
Primary: Postoperative Pain Intensity — 33; 42 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=122 Percutaneous Auricular Neuromodulation for Postoperative Analgesia
Postoperative Pain, Acute
Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 3 N=234 OxyNorm Capsules in Post-Operative Pain Study
Postoperative Pain
Primary: Visual Analogue Scale (VAS) in Resting Stage at 6hour (6hour±20 Minutes After Administration of First Dose) — 46.21; 45.48; 20.21; 19.94 units on a scale
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
Phase 4 N=66 IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative Pain
Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg
Phase 3 N=204 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Hemorrhoids
Primary: Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores — 359; 396 Units on a scale*hours
Phase 4 N=64 High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase
Hip Dysplasia · Postoperative Complications
Primary: Number of Participants With Moderate to Severe Postoperative Pain — 26; 22 Participants — p=0.248
Phase 4 N=204 IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair
Pelvic Organ Prolapse
Primary: Change From Baseline in Postoperative Pain — 20.5; 29.2; 20.7; 20.1 units on a scale — p=<0.05
N/A N=160 Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
Postoperative Pain
Primary: Opioid Consumption in the 0-48 Hour Study Periods. — 10; 5; 10; 5 milligram morphine equivalents (MMEQ)
Phase 4 N=67 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Pain · Postpartum Depression
Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale
N/A N=200 Non-invasive Assessment of Immediate Postoperative Analgesia Using Analgesia/Nociception Index (ANI)
Postoperative Pain
Primary: Analgesia/Nociception Index (ANI) — 73; 49 units on a scale
Phase 4 N=70 Perioperative Administration of Pregabalin for Pain After Mastectomy
Pain, Postoperative
Primary: Pain Scores (Verbal Numerical Rating Scale;VNRS) During Postoperative Hours. — 7; 5; 6; 5 Units on a scale
N/A N=364 Predictors of Postoperative Pain
Postoperative Pain
Primary: Visual Analog Scale (VAS) Pain Score — 38.16 mm
N/A N=7 Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Postoperative Pain
Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline
Phase 2 N=120 Local Anesthetics on Postsurgical Analgesia Following Posterior Colporrhaphy
Postoperative Pain
Primary: Change in Vaginal Pain Scores Using the Defense and Veterans Pain Rating Scale (Visual Analog Scale) Between Bupivacaine Alone Versus Exparel® Following Posterior…
Phase 4 N=200 Assessment and Prevention of Acute Post-herniotomy Pain
Hernia
Primary: Analgesic Efficacy — 26.5; 32.3 percentage of patients with NRS≥4
Phase 4 N=99 Perioperative Administration of Pregabalin for Pain After Robot-assisted Endoscopic Thyroidectomy
Pain, Postoperative
Primary: Pain Scores (VNRS) at 1, 6, 24, 48 Hours Postoperatively. — 6; 6; 3; 2 VNRS
N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
N/A N=70 Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery
Pain
Primary: Quality of Recovery at 24 Hours(QoR-40 Instrument) — 189; 183 units on a scale — p=.01
Phase 2 N=239 Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy
Acute Postoperative Pain · Bunionectomy
Primary: Mean Area Under the Curve (AUC) of the Numeric Rating Scale (NRS) of Pain Intensity Scores From Time 0 (When First Dose on Day 1 is Administered) Through 24 Hours…
Phase 4 N=515 PO vs. IV Acetaminophen Given Perioperatively for 24 hr Post-op Pain Control Following Total Hip or Knee Replacement
Post-op Pain
Primary: Total Post-operative Use of Opioids — 21.7; 21.7 Morphine milligram equivalents (MME)
Phase 4 N=180 Minimal Opioid Use After Total Hip Replacement (THR)
Osteoarthritis, Hip
Primary: Opioid Use — 30; 22.5; 15 Oral Morphine Equivalent (mg)
N/A N=146 Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia
Pain
Primary: Average Pain Score at Rest — 3.1; 2.9 Units on a scale
N/A N=148 Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
Pain, Postoperative
Primary: Cumulative Postoperative Opiate Consumption — 2.9; 3.8; 5.7 mg
N/A N=50 Inflammation and Postoperative Tramadol Analgesia
General Surgery
Primary: Analgesic Affect of Tramadol After Major Abdominal Surgery — 7; 5; 5; 3 Score on a scale
N/A N=711 Efficiency And Quality In Post-Surgical Pain Therapy After Discharge
Opioid Use · Opioid Dependence · Opioid Misuse
Primary: Cumulative Weekly Opioid Intake After Discharge — 30; 30; 20; 10 Morphine milligram equivalents
Phase 4 N=119 Intravenous Acetaminophen for Non-Narcotic Postoperative Pain Management Following Knee Arthroscopy
Pain, Postoperative
Primary: Postoperative Pain Levels — 1.3160; 2.1362 score on a scale