N/A N=170 Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Acute Psychological Stress
Primary: Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) — 0.265; 0.287 mL/(kg·min)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=72 Biological Response to Brief Psychological Challenge
Acute Inflammatory Response to Psychological Stress
Primary: Cell-free Mitochondrial DNA — 165.79; 405.56; 175.45; 164.45 Copies per uL — p=0.86
N/A N=58 Cranial Electrotherapy Stimulation and Acute Stress
Anxiety State
Primary: Change From Baseline in Heart Rate During Stressful Lethal Force Decision Making Task — 98.5; 111; 100.0; 114 bpm — p=.012
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
N/A N=323 Stress, Salt Excretion, and Nighttime Blood Pressure
Blood Pressure · Psychological Stress
Primary: Ratio of Awake-to-asleep Urinary Sodium Excretion Rate (Aim 1) — 1.4 Ratio of awake-to-asleep — p=0.0032
N/A N=6 Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System
Sedentary Behavior · Cardiovascular Risk Factor · Mental Stress
Primary: Mean Change in Brachial-femoral Pulse Wave Velocity (bfPWV) — -0.26; 0.22 m/s
Phase 4 N=92 Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?
Stress, Psychological · Inflammation · Cortisol
Primary: Change in Interleukin-6 (IL-6) — .05; .16; .31; .24 log(picograms/mL)
Phase 2 N=65 Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects
Acute Stress Reaction
Primary: Acute Stress Measured by Tension — 3089.4; 3253.4 mm*min — p=0.1233
N/A N=17 Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
Middle-aged Adults · Major Depressive Disorder
Primary: Nitric Oxide (NO)-Mediated Endothelium-dependent Dilation (EDD) — 70; 74 percentage — p=>0.05
N/A N=53 Stress in Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Psychological
Primary: Retention Rate — 23; 25; 19; 22 Participants
Phase 2 N=66 Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects
Acute Stress Reaction
Primary: Acute Stress Measured by Tension — 3335.7; 3360.3 mm*min — p=0.7726
N/A N=97 Influence of Stress on Encoding and Prediction
Stress · Learning, Spatial
Primary: Changes in fMRI Signal — 0.261; -0.264 Pearson's rho — p=0.023
N/A N=23 Stress and the Nervous System
Autonomic Nervous System · Baroreflex · Stress, Physiological
Primary: Cardiovagal Baroreflex Sensitivity (Modified Oxford Technique) — 17.75; 16.90; 14.42; 17.27 ms/mmHg
N/A N=112 The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk
PTSD
Primary: Change From Baseline to Post-Intervention in 24-hour Heart Rate Variability (HRV) Estimated From the Standard Deviation of the Interbeat Interval of Normal Sinus Beats…
Phase 3 N=60 Pilot Study on the Efficacy of Pascoflair in an Acute Stressful Situation (TSST)
Healthy · Stress
Primary: VAS Insecurity (During) — 56.87; 60.93 mm
Phase 4 N=226 Stress Neuroadaptation in Tobacco Dependence
Nicotine Dependence
Primary: Overall Stressor Reactivity — 25.1; 22.5; 32.3; 16.9 microvolts
N/A N=1,418 Effects of Arousal and Stress in Anxiety
Healthy Volunteers
Primary: Go Correct Hits Followed by Button Press — 90.9; 91.6 Percentage of correct responses
N/A N=120 College Student Stress: Transitions Over Time
Depressive Symptoms
Primary: Percentage of Eligible Participants Who Agreed to Participate in the Trial — 120 Participants
N/A N=119 Stress Response in Opioid Use Disorder
Opioid-use Disorder
Primary: Change in Negative Affect — 1.67; 1.25; 3.60 scores on a scale
N/A N=28 Resolving Psychological Stress
Post-Traumatic Stress Disorder · Alcohol Use Disorder
Primary: PTSD Symptoms Using PTSD Checklist-5 (PCL-5) at Baseline and 15 Days — 33.2; 36.6; 31.2; 28.2 units on a scale — p=0.322
Phase 2 N=24 Effect of Ketamine on Laboratory-induced Stress in Healthy Subjects
Healthy Volunteers
Primary: Change in The Profile of Mood States - Bipolar Version (POMS - Bi) Composed-Anxious Subscale — -6.8; -11.9 score on a scale
N/A N=71 Yoga and Aerobic Exercise Effects on Cognition
Stress, Psychological
Primary: N-back Task (Working Memory) — 827.50; 844.26; 832.60 Milliseconds
Phase 2 N=241 Psychological Influences on Postoperative Recovery
Care, Postoperative · Pain, Postoperative · Surgical Procedures, Operative
Primary: Modified Yale Preoperative Anxiety Scale — 41.59; 37.44; 46.17; 33.65 Score on mYPAS scale — p=.02
N/A N=53 Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
Stress · Psychological Stress · Child Maltreatment
Primary: Change in Stressor Demands, as Measured by Ecological Momentary Assessment (EMA) — -.0950; .0009 score on a scale
N/A N=120 Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects
Healthy · Stress, Psychological
Primary: Change of the Heart Rate (HR) in Response to the Trier Social Stress Test (TSST) — 74.84; 74.34; 88.15; 86.69 bpm — p=0.757
N/A N=99 Investigating the Neural Systems That Support the Beneficial Effects of Positive Emotion on Stress Regulation
Behavior
Primary: Mood Ratings (Pos) — 1.34; 1.04; .96; .83 units on a scale
Phase 2 N=121 Stress Management for Patients With Multiple Sclerosis
Multiple Sclerosis
Primary: No.of Gd+ Lesions From Week 8 to Week 24 — 46; 33; 5; 13 participants — p=0.04
N/A N=179 Mobile Self-Management Program for Stress Reduction in Young Adults
Stress (Psychology)
Primary: Stress at Week 8 — 19.41; 18.35 score on a scale
N/A N=82 Brief Mindfulness Meditation Course to Reduce Stress in Healthcare Professionals
Stress, Professional · Stress, Psychological
Primary: Perceived Stress Scale (PSS) — 19.63; 18.80; 17.29; 18.54 score on a scale
N/A N=28 Mindfulness-Based Stress Reduction for Adults With Low-Risk Chest Pain Associated With Anxiety
Chest Pain · Anxiety · Mindfulness
Primary: Mean Difference in Generalized Anxiety Disorder -7 (GAD-7) — 5.3; 3.2 score on a scale — p=0.82