N/A N=56 Ear Acupuncture for Acute Sore Throat.
Acute Sore Throat
Primary: Reduction in Pain — 6.4; 6.2; 2.6; 6.0 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=249 Double-blind Trial to Investigate Efficacy and Tolerance of Ambroxol Lozenges 20 mg in Sore Throat
Pharyngitis
Primary: Sum of Pain Intensity Difference (SPIDnorm)-Time-weighted Average of the Pain Intensity Difference (PID) From Pre-dose Baseline Over the First 3 Hours After the First…
Phase 3 N=229 Clinical Study for Comparative Assessment of Efficacy and Safety of Angal S, Topical Spray and ANTI-ANGIN® FORMULA, Topical Metered Spray in Treatment of Patients With Uncomplicated Acute Infectious and Inflammatory Diseases of the Pharynx, Accompanied by a Sore Throat
Sore Throat
Primary: Percentage of Patients Without Sore Throat According to the Tonsillopharyngitis Severity Score (TSS) — 89.47; 75.65; 7.02; 19.13 Percentage of Participants — p=0.00001
Phase 3 N=250 Efficacy and Safety of a Sore Throat Lozenge Containing Lidocaine and Cetylpyridinium Chloride in Patients With Sore Throat Due to a Common Cold.
Sore Throat Due to a Common Cold
Primary: Change From Baseline Sore Throat Pain Intensity — -27.4; -26.9 mm
Phase 3 N=228 A Local Clinical Study for the Comparative Evaluation of Efficacy and Safety of Angal, Lozenges [Menthol] and ANTI-ANGIN® FORMULA, Lozenges, in Treatment of Patients With a Sore Throat
Sore Throat
Primary: Percentage of Participants Without Sore Throat According to TSS Score — 84.35; 73.21; 13.91; 17.86 percentage of participants — p=0.028
Phase 3 N=198 A Study of Flurbiprofen 8.75 mg Lozenge in Patients With Pharyngitis
Pharyngitis
Primary: Time Weighted Sum of Pain Intensity Differences (SPID) in Sore Throat Pain Intensity Scale (STPIS) Over the 24 Hours Post-baseline (STPIS SPID24) — -522.9; -326.5 units…
Phase 3 N=204 A Study of Flurbiprofen 8.75 mg Lozenge in Patient With Pharyngitis
Pharyngitis
Primary: Time Weighted Sum of Pain Intensity Differences (SPID) in Sore Throat Pain Intensity Scale (STPIS) Over the 24 Hours Post-baseline (STPIS SPID24) — -473.7; -322.3 units…
N/A N=200 SPOTFIRE Sore Throat (ST) Study
Pharyngitis, Infective
Primary: Aim 2 Clinical Outcome: Summary of Test Results — 1; 6; 14; 13 Participants
Phase 3 N=269 Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat
Pharyngitis
Primary: Sum of Sore Throat Pain Intensity Difference (SPID2) on Swallowing at 2 Hours Post-First Dose — 21.0; 9.4 units on a scale * hours — p=0.0003
Phase 4 N=120 Post Operative Sore Throat and Dexamethasone
Sore Throat · Pain
Primary: Subjects Assessment of Sore Throat Pain at 24 Hours — 4; 4; 5 units on a scale (1 to 5) — p=<0.001
N/A N=141 Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique
Post Operative Sore Throat · Dysphagia · Hoarseness
Primary: Incidence of Tracheopharyngeal Symptoms — 53; 49 participants
N/A N=192 The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid Surgery
Anesthesia Intubation Complication · Tracheal Disease
Primary: The Incidence of Postoperative Sore Throat(POST) Using Ketorolac and Dexamethasone in Womend After Thyroidectomy — 43; 44; 42; 41 Participants
N/A N=265 Study of Count Coughs in Subjects With Acute Upper Respiratory Tract Infections
Infection
Primary: Number of Cough Bouts Over 4-hour Postdose Period — 139.6; 131.3; 126.4 Cough bouts — p=0.216
N/A N=2,822 Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine
Respiratory Tract Infections
Primary: Body Temperature — 183; 170; 13; 2617 Participants
Phase 3 N=51 Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Phenylephrine 10mg + Guaifenesin 200 mg Syrup in Patients Suffering a Upper Respiratory Tract Infection (URTI)
Upper Respiratory Infections
Primary: Warming Sensation Caused by the Excipient IFF Flavor 316 282, in a Syrup Containing Paracetamol 500 mg + Phenylephrine 10mg + Guaifenesin 200 mg Per 30 ml Syrup — 34.6 mm
Phase 3 N=57 Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough
Common Cold
Primary: Onset of Warming Sensation — 0.233 Minutes
Phase 3 N=775 Phase 3 Clinical Study for the Treatment of Cold Sore
Herpes Labialis
Primary: Time to Healing (TTH) of Vesicular Primary Lesion — 7.00; 7.32 Days — p=0.015
Phase 3 N=50 Management of Post-Tonsillectomy Pain in Pediatric Patients
Pain, Postoperative · Tonsillar Hypertrophy · Tonsillitis
Primary: Number of Participants With FLACC Pain Scores ≥7 From POD 1 Through POD 3 — 1; 1 participants
Phase 1 N=25 An Exploratory Study to Investigate the Inflammatory Response During a Cold Sore Episode
Herpes Labialis
Primary: Mean Change From Baseline in Blood Flow — 2558.65; 3470.13; 809.88; 960.86 Perfusion Units — p=0.3061
Phase 4 N=166 Treatment of Acute Sinusitis
Acute Respiratory Infections · Acute Rhinosinusitis
Primary: SNOT-16 Score (Sino-Nasal Outcomes Test) at Day 3 — 1.12; 1.14 Units on a scale — p=0.83
Phase 3 N=56 Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Pseudoephedrine 30 mg Syrup in Patients Suffering a URTI
Upper Respiratory Infections
Primary: Warming Sensation Caused by the Excipient IFF Flavor 316 282, in a Syrup Containing Paracetamol 500 mg + Pseudoephedrine 30 mg Per 30 ml Syrup — 34.2 mm
Phase 4 N=291 Acute Otitis Media (AOM) Therapy Trial in Young Children
Acute Otitis Media
Primary: The Time to Resolution of Symptoms, Defined as Acute Otitis Media-Severity of Symptoms (AOM-SOS) Score of 0 or 1, According to Treatment Assignment — 20; 9; 1; 2…
Phase 3 N=120 Pediatric Tonsillectomy Pain Reduction Study
Postoperative Pain
Primary: Total Number of Post-operative Doses of Analgesics. — 12; 12; 14 number of doses
Phase 2 N=20 Povidone-Iodine Vs Essential Oil Vs Tap Water Gargling For COVID-19 Patients
COVID-19
Primary: Number of Participants With Early Viral Clearance — 5; 4; 1; 0 Participants
N/A N=100 Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms
Xerostomia
Primary: Mean Response to the Question 1 'Relieving the Discomfort of Dry Mouth' in Product Performance and Attributes Questionnaire 3 (PPAQ3) at 120 Minutes(Mins) Post Treatment…
Phase 3 N=326 Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children
Acute Otitis Media
Primary: Effectiveness of Viscous-adherent Xylitol Syrup in Reducing Episodes of Clinically-diagnosed Acute Otitis Media — 66.9; 63.3 percentage of particpants — p=0.6
N/A N=421 Trulimax (Azithromycin ) Non-Interventional Study In Acute Bacterial Upper Respiratory Tract Infections
Upper Respiratory Tract Infections
Primary: Number of Subjects With an Investigator Assessment of Clinical Outcome (Success/Failure) at End of Study — 275; 133 participants
Phase 1 N=36 Immune Response and General Immune Health in Subjects Infected With Herpes Simplex Virus Type 1 (HSV-1)
HSV · Herpes Labialis
Primary: Ratio of Absolute Gene Expression of IFNG and IL5 in PBMCs Between 8 Weeks and Baseline — 10.073; 11.380; 10.711; 11.431 q-RT-PCR crossing threshold cycle (Ct)
Phase 3 N=32 Aztreonam for Pharyngeal Gonorrhea
Gonorrhea of Pharynx · Gonorrhea
Primary: Treatment Efficacy of Pharyngeal Gonorrhea as Defined as the Proportion of Study Participants With Positive Pharyngeal Gonorrhea Culture at of Enrollment Whose Test of…
Phase 3 N=122 Placebo-Controlled Onset-of-Action Study of Flurbiprofen Utilizing the Double-Stopwatch Method
Acute Pharyngitis · Sore Throat
Primary: Kaplan-Meier Estimates for Time to Meaningful Pain Relief — 42.917; NA minutes