N/A N=269 Complete Histologic Resection of Adenomatous Polyps?
Adenomatous Polyps
Primary: Percent of Incompletely Resected Adenomatous Polyps — 10.1 percentage of incomplete resection
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=46 Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer
Attenuated Familial Adenomatous Polyposis · Familial Adenomatous Polyposis
Primary: Mean Percent Change in Duodenal Polyp Burden — -29.6 percent change in Duodenal Polyp Burden
N/A N=44 Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis
Primary: Number of Polyps — 18.6; 22.6 Number of Polyps
Phase 2 N=44 Curcumin in Treating Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis
Primary: Polyp Number — 22.6; 18.6 polyps — p=0.58
Phase 2 N=92 A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients
Adenomatous Polyposis Coli
Primary: Change in Duodenal Polyp Burden From Baseline to 6 Months — -8.5; 8.0 mm — p=<0.001
Phase 2 N=112 Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis
Colorectal Cancer · Familial Adenomatous Polyposis
Primary: Percent Change in the Number of Polyps Greater Than or Equal to 2mm in Diameter in Focal Area(s) of the Colorectum — -1; -11; -1; -13 percentage change in polyp count
Phase 3 N=171 Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis
Primary: Number of Subjects With Any FAP-related Event. — 18; 23; 22; 2 Participants — p=0.1210
Phase 2 N=4 Sirolimus and Familial Adenomatous Polyposis (FAP)
Adenomatous Polyposis Coli
Primary: Change in Marked Polyp Size — 16; 4; 0 Size of marked polyps
Phase 2 N=47 Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers
Familial Adenomatous Polyposis
Primary: 13-HODE Colonic Tissue Levels — 14.56; 18.83; 23.02; 20.03 ng/mg tissue protein
N/A N=40 Hybrid APC Assisted EMR for Large Colon Polyps
Colon Polyp · Colon Adenoma · Colon Cancer
Primary: Percentage of Participants Having Complete Resection — 40 Participants
Phase 3 N=58 Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA
Familial Adenomatous Polyposis Coli · FAP
Primary: Absolute Change in the Number of Polyps Measured in a Focal Area of the Rectum. — -0.5; 0.5 Change from baseline number of polyps. — p=0.005
Phase 2 N=46 Study of the MUC1 Peptide-Poly-ICLC Adjuvant Vaccine in Individuals With Advanced Colorectal Adenoma
Risk for Colorectal Cancer
Primary: Number of Participants With Anti Muc-1 Antibody — 39 participants
N/A N=386 Efficacy of Segmental Examination Twice of the Proximal Colon on Adenoma Detection
Colonic Polyps
Primary: Difference of Adenoma Detection Rate in the Proximal Colon Among 2 Group. — 0.236; 0.331 proportion of participants
N/A N=35 Anthocyanin Extract and Phospholipid Curcumin in Colorectal Adenoma
Colorectal Adenoma · Risk Reduction
Primary: Change in Beta Catenin Expression — 100; 100; 100; 100 percentage of positive cells
N/A N=740 I-scan for Adenoma Detection
Colorectal Adenomatous Polyps
Primary: Number of Participants With Conventional Adenoma and Sessile Serrated Adenoma/Polyp Detected — 208; 171 Participants
N/A N=1,262 A 4-arm Clinical Trial of Fuse®, EndoCuff™, EndoRings™ and Standard Colonoscopy
Colorectal Neoplasms
Primary: Adenomas Per Colonoscopy — 1.53; 1.82; 1.55; 1.30 Adenomas per Colonoscopy
Phase 2 N=45 Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or Adenoma
Adenomatous Polyp · Recurrent Colon Cancer · Recurrent Rectal Cancer
Primary: Change in ACF pERK Levels
N/A N=14,263 Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study
Colorectal Cancer · Advanced Adenocarcinoma · Serrated Polyp
Primary: ColoSense Sensitivity for Colorectal Cancer (CRC) — 25; 2 Participants
N/A N=194 Adenoma Detection Rate With a New Pediatric Colonoscope With a Short Turn Radius (Pentax Retroview) Compared With a Standard Pentax Pediatric Colonoscope
Colonoscopy
Primary: Percentage of Patients With At Least One Adenoma — 63; 68 Participants
N/A N=384 Post-resection Treatment of Large Colon Polyps
Recurrence
Primary: Recurrence — 10; 5; 24 Polyps
N/A N=1,410 Gastroenterology Artificial INtelligence System for Detecting Colorectal Polyps (The GAIN Study)
Colon Adenoma · Colon Polyp · Colon Lesion
Primary: Difference in Adenomas Per Colonoscopy (APC) — 0.60; 0.74 Resected adenomas — p=0.0002
N/A N=1,148 Does Cap Assisted Colonoscopy Improve Detection of Adenomatous Polyps? (CAP Trial)
Adenomatous Polyps
Primary: Mean Number of Adenomas — 0.82; 0.89 adenoma per patient
Phase 2 N=45 Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI
Adenomatous Polyp · Colorectal Cancer · Obesity
Primary: Change in Activated S6serine235 (i.e., the Ratio of pS6serine235/S6serine235) — 0.0228 weighted ratio of staining cells — p=> 0.773
Phase 2 N=40 Evaluation of Surgically Resected Colorectal Adenomas and Carcinomas After 7 Days Pretreatment With Celecoxib
Colorectal Adenoma · Colorectal Carcinoma
Primary: Number of Subjects Witha Change (IMPROVEMENT) in Colo-rectal Adenocarcinoma as Measured by Cyclooxygenase-2 Activity After 7 Days of Celecoxib — 2.0; 2.0 Participant
N/A N=126 Comparison of Colon Adenoma Detection Rate Using Two Distal Colonoscope Attachments
Colon Cancer Screening · Colon Polyps · Colon Adenomas
Primary: Adenoma Detection Rate — 52.4; 40.5; 54.8 percentage of adenomas detected
Phase 4 N=480 Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Colorectal Neoplasms
Primary: Number of Participants With Detected Proximal Diminutive (<10 mm) Adenoma Detection Rate — 86; 89; 83; 38 participants
Phase 1 N=24 Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis
Primary: Change From Baseline to End of Study in Number of Rectal Polyps — -5.4; -1.6; -3.5 polyps — p=0.065
N/A N=427 Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas
Sessile Serrated Adenoma
Primary: Sessile Serrated Adenomas — 42; 59 colonoscopies
N/A N=739 CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy
Polyps · Adenoma Colon · Colorectal Polyp
Primary: To Evaluate Whether Using the CADDIE System Improves Endoscopist Detection of Adenomas During Colonoscopy. — 33.30; 25.20 ADR (% of participants)
Phase 2 N=19 CAPOX in KRAS Wild-Type Advanced Adenocarcinoma of the Small Bowel or Ampulla of Vater
Gastrointestinal Cancer
Primary: Response Rate (RR) — 19 Participants