N/A N=17 Pediatric Aggression and Violence
Pediatric Aggression and Violence
Primary: Salivary Hormone Correlation With Brief Rating of Aggression by Children and Adolescent (BRACHA) Score — 0.8; 0.4; 0.3; 0.4 ul/dL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=203 Preventing Aggression in Veterans With Dementia
Dementia · Aggression · Pain
Primary: Number of Participants With Aggression as Determined by the Cohen-Mansfield Agitation Inventory (Aggression Subscale) — 8; 14; 9; 17 participants — p=0.13
N/A N=36 Group CBT for Aggression in Veterans
Aggression · Anger · Posttraumatic Stress Disorder
Primary: Change in Mean Scores on the Conflicts Tactics Scale (CTS) From Baseline to Post-treatment, 3 Month and 6 Month Follow-up. — 0.50; 1.24; 0.22; 1.06 units on a scale…
Phase 2 N=132 Treatment for Aggression and Agitation in Patients With Alzheimer's Disease
Alzheimer's Disease
Primary: Mean Change From Baseline in the 4-Item Agitation/Aggression Subscale of the Neuropsychiatric Inventory (NPI-4 A/A) at Week 12 — -5.4; -6.2 units on a scale
N/A N=228 Aggression Prevention Training for Caregivers of Persons With Dementia (APT)
Dementia · Pain · Alzheimer's Disease
Primary: Number of Participants With Aggression as Per the Cohen Mansfield Agitation Inventory, Aggression Subscale — 29; 23 Participants — p=0.29
Phase 4 N=168 Treatment of Severe Childhood Aggression (The TOSCA Study)
Attention Deficit Disorder With Hyperactivity
Primary: NCBRF-TIQ D-Total Score — 43.5; 42.1; 24.9; 25.9 units on a scale
N/A N=24 Using Emotion Regulation to Decrease Aggression in Veterans With PTSD
Chronic Post-Traumatic Stress Disorder
Primary: Overt Aggression Scale — 14.2 events
N/A N=209 Emotion Regulation Interventions for Alcohol-Related Sexual Aggression
Sexual Aggression · Heavy Drinking
Primary: Sexual Aggression Intentions — 1.58; 1.90; 2.18; 1.53 score on a scale — p=.041
N/A N=84 The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
Antisocial Behavior · Aggression
Primary: Change in Antisocial Behavior Inclinations at 24 Hours — 1.41; 3.05 score on a scale
N/A N=22 Treatment of Aggression, Anger and Emotional Dysregulation in Borderline Personality Disorder
Borderline Personality Disorder
Primary: Self-Report of Difficulties in Emotion Regulation (DERS) — 101.5; 54.8; 120.5; 56.6 units on a scale — p=<0.004
Phase 1 N=8 Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
Autism Spectrum Disorder · Aggression · Irritability
Primary: Change From Baseline in Aberrant Behavior Checklist Irritability Subscale (ABC-I) — -12; -7 units on a scale — p=.44
N/A N=32 The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
Antisocial Behavior · Aggression
Primary: Number of Pins Inserted Into a Virtual Voodoo Doll After 48 Hours — 3.77; .64 pins
N/A N=5,233 An Evaluation of an Integrated Approach to Prevention and Early Intervention in the Elementary School Years
Aggression
Primary: Change in Direct Classroom Observations of Student Behavior Between Pre-test and Post-test, 6 Months After the Pre-test. — 0.42; 0.446; 0.453; 0.004 percentage of…
Phase 2 N=200 Oxytocin, Alcohol Craving, and Intimate Partner Aggression
Alcohol Use
Primary: Change in Alcohol Craving — 0.90; 1.21 score on a scale
N/A N=61 Mindfulness for Anger in Veterans With PTSD
Anger · Aggression
Primary: State Anger Scale — 27.34; 26.88; 23.47; 25.67 units on a scale — p=.14
N/A N=119 Violence Prevention for Middle School Boys
Intimate Partner Violence
Primary: Change in Dating Violence (DV) Perpetration From Baseline to 9 Months — 46; 40; 14; 14 Participants
Phase 3 N=292 Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 2)
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: Efficacy and Safety of SPN-810 on the Frequency of Impulsive Aggression (IA) Measured by the Impulsive Aggression Diary — -54.12; -51.64 Percent Change of IA behaviors…