N/A N=28 The Influence of Antibiotic Prophylaxis on Intraoperative Prosthetic Joint Infection Cultures
Prosthetic Joint Infection
Primary: Positive Cultures — 7; 7 cultures
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=146 Antibiotic Prophylaxis in Orthopaedic Traumatology
Fractures, Closed · Wounds and Injuries
Primary: Number of Participants With Total Wound Infections — 4; 9 participants — p==0.12
N/A N=219 Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
Ureteral Obstruction · Neoplasms · Acute Kidney Injury
Primary: Urinary Tract Infection After Percutaneous Nephrostomy Procedure — 5; 10 Percutaneous nephrostomy procedure — p=0.548
Phase 2 N=50 Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions
Premalignant Vulvar Lesion · Benign Vulvar Lesion
Primary: Vulvar Wound Complications Compared Between the Two Arms — 6; 10 Participants
N/A N=276 Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections
Surgical Site Infection
Primary: Number of Participants With Surgical Site Infections — 11 participants
Phase 2 N=90 Continuous Antibiotic Prophylaxis in Colorectal Surgery
Surgical Site Infection
Primary: Number of Patients With a Surgical Site Infection — 10; 13 Participants
N/A N=400 Timing of Antibiotic Prophylaxis for Cesarean Deliveries
Infection
Primary: Endometritis and Wound Infection — 6; 4 patients infected
Phase 2 N=224 Preventing Complications in Cleft Palate Repair With Antibiotics
Cleft Palates
Primary: Number of Participants With Fistula or Delayed Wound Healing Following Palatoplasty — 3; 2; 18; 21 Participants
N/A N=251 Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy
Antibiotic Prophylaxis
Primary: Number of Participants Who Experienced At Least One Postoperative Infectious Complication — 13; 8 Participants — p=.26
Phase 4 N=57 Effects of Antibiotic Prophylaxis on Recurrent UTI in Children
Urinary Tract Infection · Recurrent Urinary Tract Infection
Primary: Changes to the Urinary Microbiota — 3; 2; 1 participants
Phase 4 N=510 Antibiotic Prophylaxis for Transrectal Prostate Biopsy
Infection
Primary: Number of Participants With Post-biopsy Infection. — 6; 3 participants — p=<0.05
Phase 4 N=86 A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
Nephrolithiasis · Urinary Tract Infections
Primary: Number of Participants That Developed Sepsis After Surgery — 5; 6 Participants
N/A N=513 Perioperative Antibiotic Choices for Surgical Prophylaxis in Penicillin-allergic Pediatric Patients
Penicillin Allergy
Primary: Number of Subjects With Antibiotic Related Adverse Event — 12 participants
Phase 4 N=18 Prophylactic Antibiotics for Prevention of Wound Complications Following Vulvectomy
Wound Infection
Primary: Wound Complications — 3; 2 Participants
Phase 4 N=163 Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
Urinary Tract Infection
Primary: Urinary Tract Infections — 18; 10 participants
N/A N=67 Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair
Hypospadias
Primary: Number of Participants With Urinary Tract Infection — 30; 22; 0; 0 Participants
Phase 3 N=1,010 Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.
Sick Sinus Syndrome · Complete Heart Block · Syncope
Primary: Number of Patients With a Major Cardiac Implantable Electronic Devices (CIED) Infection — 5; 6 Participants
Phase 4 N=756 Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
Postpartum Sepsis · Postpartum Endometritis · Postpartum Fever
Primary: Number of Participants Who Experienced Composite Peripartum Infection or Death — 15; 17; 24 Participants
Phase 4 N=300 Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair
Inguinal Hernia
Primary: Rate of Post-operative Infection
Phase 4 N=184 Preoperative Antibiotics for Carpal Tunnel Release Surgery
Carpal Tunnel Syndrome
Primary: Number of Participants With Surgical Site Infection — 0; 0; 0 Participants
N/A N=26 A Pilot Study on the Use of Prophylactic Antibiotics for EUS-guided Pancreatic Cyst Aspiration
Pancreatic Cysts
Primary: Number of Patients With Pancreas Cyst Infection After EUS-guided Pancreatic Cyst Aspiration — 0; 0 participants
N/A N=181 Vancomycin and Daptomycin Plus Cefazolin for Preoperative Vascular Surgery Prophylaxis
MRSA Infections
Primary: Overall Number of Participants With Methicillin-resistant Staphylococcus Aureus (MRSA) Infections. — 2; 0; 4 participants
Phase 4 N=372 The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients.
Breast Cancer
Primary: Number of Patients With Body Mass Index (BMI) Over 25 Who Developed Surgical Site Infection (SSI) in Groups Who Received Antibiotic Prophylaxis (Prophylaxis Group) and…
Phase 4 N=401 Topical Antibiotic Prophylaxis for Eyelids
Antibiotic Side Effect · Eyelid; Wound · Eyelid Diseases
Primary: Number of Participants With Surgical Site Infections — 0; 5 Participants — p=0.025
Phase 4 N=89 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial
Sinusitis
Primary: Sinonasal Outcome Test - 22 — 31.3; 31.0 score on a scale
Phase 1 N=1,999 Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty
Osteoarthritis
Primary: Rate of Periprosthetic Infection (PJI) After Elective Total Joint Arthroplasty. — 7; 0; 3; 2 Participants
Early Phase 1 N=186 Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity · Induction of Labor Affected Fetus / Newborn
Primary: Number of Participants With Cesarean Delivery — 27; 37 Participants
Phase 4 N=160 Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
Supracondylar Humerus Fracture · Post Operative Wound Infection
Primary: Number of Participants With the Presence of Post-Operative Infection — 2; 2 Participants
Phase 3 N=22 Regional Prophylactic Vancomycin in Revision Total Knee Replacement
Arthropathy of Knee Joint
Primary: Mean Concentration of Vancomycin in Subcutaneous Fat — 94.1; 3.2; 88.3; 5.0 µg/g — p=<0.0001
Phase 4 N=51 Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk Antibiotics
Clostridium Difficile Infection · Prophylaxis · Vancomycin
Primary: Clostridium Difficile Infection Occurrence — 2; 0 Participants