Phase 3 N=201 Evaluating Improvement Strategies in Addiction Treatment
Addiction
Primary: Change in Average Waiting Time From First Contact to Treatment — .253; 4.610; 4.723; 3.520 Change in days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=667 LINK: Aftercare Monitoring Project
Alcohol Dependence · Drug Dependence
Primary: Rates of Substance Use — 91.1; 88.0 percentage of days
N/A N=313 Motivate: A Web-based Intervention
Eating Disorders
Primary: Number of Participants Who Attended Initial Assessment Appointment — 140; 134 Participants
N/A N=166 Improving Attendance in Community Wise
Intervention Engagement and Retention
Primary: Number of Participants Attending at Least 50% of Sessions — 8; 6; 1; 4 Participants
N/A N=345 Intensive Outpatient Versus Outpatient Treatment With Buprenorphine Among African Americans
Drug Dependence
Primary: Percentage of Participants Meeting Diagnosis of Opioid Dependence on Composite International Diagnostic Interview-2 (CIDI-2) — 20; 21 percentage of opioid dependent…
Phase 3 N=74 Smoking Cessation & Opioid Dependence Treatment Integration
Smoking Cessation · Opioid Related Disorders
Primary: Recruitment, Assignment to Treatment, and Retention Rates — 40; 33; 15; 32 Participants
N/A N=18 Atomoxetine/Attention Deficit/ Hyperactive Disorder (ADHD)/Substance Use Disorder (SUD)in a Residential Treatment Facility
Attention Deficit Hyperactivity Disorder
Primary: Change in Adult ADHD Investigator Symptom Rating Scale Score — 17.3 units on a scale
N/A N=216 Treatment Advocacy Intervention for HIV-Positive African Americans
HIV
Primary: Medication Adherence — 77.96; 80.13; 64.87; 76.13 Percentage of doses taken — p=.005
Phase 2 N=183 Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment
Substance Use Disorders · Alcohol Abuse · Alcoholism
Primary: Abstinence Rate (During the Preceding 90 Days) at 12 Months Follow-up Point as Assessed by the Form-90 — 40; 38; 47; 51 participants
N/A N=88 Substance Use Treatment and Recovery Team (START)
Opioid-use Disorder · Opioid-Related Disorders · Alcohol Use Disorder
Primary: Number of Patients With In-hospital Initiation of Medication for OUD or AUD — 22; 9 Participants — p=<.001
N/A N=504 Service Development: Assessing Non-attendance Rates in Outpatient Clinics
Asthma · Sleep Apnea Syndromes · Tuberculosis
Primary: Attendance Rates at Respiratory Outpatient Clinics — 183; 89 Participants — p=0.004
N/A N=330 The Effect of a Contingency Management Intervention on Substance Use
Substance Use Disorders
Primary: Number of Negative Breath Alcohol and Urine Drug Screens Out of Possible 16 — 11.93; 10.39 negative alcohol and drug screens — p=<.001
N/A N=400 Talk Therapy by Phone to Promote Treatment for Alcohol Problems
Alcohol Use Disorder · Alcohol Abuse
Primary: Average Drinks Per Drinking Day — 5.5; 5.4 drinks per occasion — p=0.746
N/A N=31 Improving Cardiac Rehabilitation Session Attendance: A Randomised Controlled Trial
Cardiac Rehabilitation
Primary: CR Adherence — 16.0; 14.4 Classes Attended
Phase 3 N=500 Adaptive Treatment for Alcohol and Cocaine Dependence
Substance Use Disorders
Primary: Treatment Engagement — 3.92; 3.50 treatment days — p=0.11
N/A N=29 Engaging Suicidal Patients in Mental Health Treatment
Suicide · Depression · Mental Health Impairment
Primary: Acceptability of Intervention Measure (AIM) — 3.96; 4.40; 3.88; 3.34 score on a scale
N/A N=193 Network Support for Alcohol Treatment 2
Alcohol Consumption
Primary: Proportion Days Abstinent (PDA) — .67; .73 proportion of days abstinent — p=<.04
N/A N=95 Treatment Engagement With Technology-assisted Treatment
Alcoholism · Substance-related Disorders · Mentally Ill Chemical Abuse
Primary: Acceptability of Treatment Based on Survey Questionnaire Completed by Participants — 8.78; 8.23 score on a scale
Phase 4 N=223 Extended Treatment for Smoking Cessation
Smoking Cessation
Primary: Expired-air CO Verified Point-prevalence Abstinence — 44; 42 participants
N/A N=325 Substance Use Treatment and Recovery Team
Opioid-use Disorder · Opioid-Related Disorders
Primary: In-hospital Initiation of MOUD Therapy — 94; 43 Participants
N/A N=282 The Improving ATTENDance to Cardiac Rehabilitation Trial
Myocardial Infarction · Heart Failure · Heart Valve Diseases
Primary: Number of CR Sessions Completed Within 6 Months in Patients Randomized to HYCR vs. Patients Randomized to Traditional CBCR (Usual Care). — 28.7; 27.6 Number of cardiac…
N/A N=832 Testing an Organizational Change Model to Address Smoking in Mental Healthcare
Nicotine Dependence
Primary: Client Reported Tobacco Medications — 48; 28; 62; 24 Participants
N/A N=150 Facilitating Aftercare for Alcohol Detox Patients
Alcohol Abuse · Alcohol Dependence
Primary: Linkage to Alcohol Behavioral Therapy Counseling (i.e., "Aftercare") — 36; 36; 32 participants
N/A N=69 Individual and Family Motivational Interviews for Substance Using Truant Teens
Substance Use
Primary: Marijuana Use Days in Past 90 Days — 35; 45; 27; 41 days
N/A N=105 Mindfulness-Based Relapse Prevention to Improve Medication Assisted Treatment Adherence and Drug-use Outcomes for Opioid Use Disorder
Opioid-use Disorder
Primary: Adherence to Medication Assisted Treatment (MAT) — 32; 17 Participants
N/A N=14 Acceptance and Commitment Therapy for Tobacco Cessation Among Psychiatric Partial Hospital Patients
Tobacco Smoking · Psychiatric Disorder · Psychiatric Hospitalization
Primary: Feasibility of Recruitment: Proportion of Smokers Seen During the Partial Hospital Visit Who Enroll in the Study — 17 Participants
Phase 2 N=48 Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment
Substance Abuse · Substance Dependence · Cognitive Impairment
Primary: Days of Sobriety in First 90 Days — 87.3; 84.64 Days of Sobriety — p=.55
N/A N=298 TeleMonitoring to Improve Substance Use Disorder Treatment After Detoxification
Enhanced Telephone Monitoring · Usual Care
Primary: Percent of Participants Who Had an Additional Inpatient Detoxification — 33; 47 Participants
N/A N=122 Adolescents With Substance Use Disorders Transitioníng From Residential Treatment to the Community
Substance Use · Adolescent Behavior
Primary: Change in Proportion of Days Used Outside of Controlled Environment — .27; .35; .35; .32 proportion of days used — p=.12
N/A N=48 SMART Effectiveness Trial
Opioid-use Disorder · Opioid Dependence · Treatment Adherence
Primary: Treatment Adherence — 16; 13 Participants