N/A N=39 A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Vocal Cord Paralysis · Phonasthenia · Presbylarynges
Primary: Change in Mean Phonation Time — 7.74; 14.08 seconds
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules
Voice Disorders in Children · Vocal Nodules in Children · Hoarseness
Primary: Change in Dysphonia Severity Index — 1.8; 1.8; 0.0 units on a scale — p=0.024
Phase 1 N=20 Bevacizumab for Treatment of Recurrent Respiratory Papillomatosis (RRP)
Recurrent Respiratory Papillomatosis
Primary: The Primary Activity Variable Was the Recurrence of Recurrent Respiratory Papillomatosis (RRP) in Bevacizumab Treated and the Un-treated Vocal Fold in the Same Patient…
N/A N=25 Stereotactic Ablative Radiotherapy for Early-stage Glottic Larynx Cancer
Glottic Carcinoma
Primary: Number of Patients With Local Failure Following SABR Treatment of Early Glottic Larynx Cancers — 2 participants
N/A N=29 Preliminary Study 1 to Test the Effects of Ambulatory Voice Biofeedback
Vocal Fold Nodules
Primary: Percent Compliance — 97.38; 95.11; 94.44; 96.08 Percentage of voicing below a threshold
Phase 2 N=21 Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia
Dysphonia Resulting From Vocal Fold Scarring · Age-related Dysphonia
Primary: Number of Participants With Any Improvement From Baseline in Mucosal Wave Grade — 14; 5 Participants
N/A N=42 Laryngeal Vibration for Spasmodic Dysphonia
Spasmodic Dysphonia
Primary: Voice Assessment During First Visit — 0.045; 0.17; 0.13; -0.47 decibel
Phase 4 N=36 Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes
Dysphonia
Primary: Change in Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) Score From Baseline to 2 Months — 0.72; 0.65 score on a scale
N/A N=55 Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients
Larynx Cancer · Laryngectomy; Status
Primary: High Speed Video Endoscopy Recordings — 53; 2; 2; 38 Participants
N/A N=11 Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders
Voice and Resonance Disorders · Vocal Fold Polyp · Vocal Cord Cyst
Primary: Change From Baseline in VHI-10 Score After 4 Sessions of Voice Therapy — 7 score on a scale — p=.0076
N/A N=125 Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
Vocal Cord Function in Neck Procedures
Primary: Frequency of Congruence of Nerve Integrity and Vocal Cord Functions — 68; 13; 17; 10 nerves at risk
N/A N=30 Evaluating the Feasibility of Acapella® Choice as a Dysphonia Treatment
Muscle Tension Dysphonia · Vocal Fold Palsy · Vocal Cord Paralysis
Primary: Change in Baseline Cepstral/Spectral Index of Dysphonia (CSID) — 1.22; 4.45; 4.56; 3.13 score on a scale
Phase 4 N=19 Use of Cidofovir for Recurrent Respiratory Papillomatosis
Recurrent Respiratory Papillomatosis
Primary: Change in Papilloma Severity — 13.2; 12; 3.7; 3.6 scores on a scale
N/A N=10 Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules
Thyroid Nodule
Primary: Change in Radiographic Volume of Thyroid Nodule From Baseline at 3, 6 and 12 Months After Laser Ablation — 63.4; 71.087 percentage of volume reduction
N/A N=24 The Effects of Respiratory Training on Voice
Muscle Tension Dysphonia
Primary: Post Training Lung Volume Initiation — 21.07; 27.04 % vital capacity relative to rest level — p=<0.0005
N/A N=47 Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia
Vulvar Intraepithelial Neoplasia (VIN)
Primary: Number of Participants With Recurrence of Dysplasia — 5; 8 Participants
N/A N=122 Detection Of Neoplastic Tissue in Barrett's Esophagus With In vivO Probe-based Confocal Endomicroscopy
Barrett Syndrome · Barrett's Syndrome · Barrett's Esophagus
Primary: Comparative Histopathology-confirmed Measures of Per Lesion Sensitivity and Per Lesion Specificity, by Using pCLE Associated With WLE, or WLE Alone, for the Detection of…
Phase 4 N=26 Treatment of Tracheostomy Granulomas
Granuloma · Tracheostomy
Primary: Success and Failure Rates for Each Treatment Method — 6; 3; 5; 3 Participants
Phase 2 N=27 Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery
Parotid Neoplasm · Thyroid Neoplasms · Head and Neck Neoplasms
Primary: Safety - The Number of Patients With ALM-488 Related Adverse Events — 0; 0; 0; 0 Participants
Phase 4 N=18 Propranolol and Botulinum Toxin for Essential Vocal Tremor
Essential Vocal Tremor · Essential Voice Tremor · Essential Tremor
Primary: Change in Quality of Life in Essential Tremor (QUEST) Questionnaire Score — 39.41; 29.50; 23.60 units on a scale
N/A N=8 Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation
Essential Tremor
Primary: Vocal Tremor Scoring System (VTSS) — 0.57; 0.57; 1; 0.43 units on a scale
N/A N=42 Assessment of the Effectiveness of Local Ablathermy Radio Frequency Bronchial Tumors Primitive
Malignant Non-small Cell Neoplasm of Lung Stage Ia
Primary: Local Tumor Control Rate 1 Year After Percutaneous Radiofrequency Ablation (RFA) — 5 Participants
Phase 1 N=22 Anatomical Relationship of Level IB Lymph Nodes to the Submandibular Gland in Cancer Patients
Carcinoma
Primary: the Number of Lymph Nodes: 1. Identified Within Each Lymph Node Group, 2.Located Within the Submandibular Gland, and 3. Within the Fibrofatty Contents Lying Deep to the…
Phase 2 N=275 OK432 (Picibanil) in the Treatment of Lymphatic Malformations
Lymphatic Malformations
Primary: Number of Participants With Clinical Success at 1 to 6 Months Post-Therapy as Assessed by Imaging — 57 Participants
N/A N=96 Vocal Cord Views With the Classical Miller, Wis-Hipple and C-MAC Size 1 Blades in Young Children
Percent of Vocal Cords (Glottic) Opening
Primary: Percentage of Vocal Cord Opening — 100; 98; 100 percent — p=<0.05
N/A N=70 The Vivaer Procedure for Treatment of the Septal Swell Bodies (SWELL)
Nasal Obstruction
Primary: Nasal Obstruction Symptom Evaluation (NOSE) Scale Mean Change — -45.3 score on a scale
N/A N=41 Vocal Warm-up and Respiratory Muscle Training
Voice Disorders
Primary: Voice Handicap Index (VHI-10) — 20.44; 13.82 units on a scale — p=0.001