N/A N=22 Bone Augmentation Techniques in Extraction Sockets
Tooth Loss
Primary: Changes in Hard Tissue Composition — 35.82; 31.76 mm
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=9 A Histomorphometric Analysis Following Sinus Augmentation Using Two Different Bone Graft Materials.
Missing Teeth
Primary: Percentage of New Vital Bone. — 16.33; 26.11; 30.5; 39.67 percentage of new vital bone
Phase 2 N=22 Bone Material Comparison in Maxillary Sinus Augmentation
Alveolar Bone Resorption · Sequela · Tooth Extrusion
Primary: Bone Density - Limited View CBCT (Cone-beam Computed Tomography) Measurements — 14.4; 1.5 percentage of bone height shrinkage
N/A N=30 Management of Traumatic Bone Defects in Tibial Plateau Fractures With Antibiotic-Impregnated Biodegradable Calcium Sulfate Beads: A Prospective Clinical Trial
Tibial Fractures · Intra-Articular Fractures · Fracture Fixation, Internal
Primary: Resorption of Study Device — 4 Participants
N/A N=32 Bone Remodeling After Immediate Implant Placement With and Without Bone Grafting
Tooth Loss
Primary: Mean Bucco-Lingual Change at 3mm — -0.84; -1.01 mm
N/A N=16 Clinical and Histological Evaluation of Deproteinizated Bovine Bone Allograft and Lyophilized Equine Bone Allograft for Sinus Lift.
Maxillary Sinus Floor Augmentation
Primary: Histomorphometric Evaluation of New Bone Formation. — 22.20; 22.84; 50.77; 46.20 percentage of millimeters
Phase 2 N=26 Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation
Tooth Loss
Primary: Bone Mineral Density of Bone Core — .79; .78 mg/mm^3
N/A N=41 An Assessment of Bone Augmentation in Post-Extraction Sockets
Unrestorable Dentition · Post-Extraction Sockets
Primary: Bone-fill in Grafted Post-extraction Sockets Versus Bone-fill in Non-grafted Post-extraction Sockets — 0.43; 0.27; 0.36; 0.28 mm
N/A N=31 A Comparison of Bone Formation With Three Different Bone Graft Materials Following Sinus Graft
Inadequate Bone Height in Maxillary Posterior Area
Primary: The Percentage of Vital Bone in a Total Amount of a Bone Specimen — 10.9; 9.1; 32.0 percentage of vital bone
N/A N=46 Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft
Bone Augmentation
Primary: Percent New Vital Bone Formation — 32.63; 47.41 percentage of vital bone
N/A N=260 MICRO Study: Detecting Bacterial Infections Related to Orthopaedic Surgical Implants
Open Reduction and Internal Fixation of Extremity Fractures
Primary: Number of Blood Samples With High Levels of Absorbance Via ELISA for Patients (Greater Than 1.5 Ratio Compared to Control Human Serum) — 48; 53 blood draw samples
N/A N=37 The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges
Alveolar Ridge Augmentation · Alveolar Ridge Preservation
Primary: New Bone Formation (in %) With the Use of Small vs. Large Particle Bone Allografts — 17.3; 25.9; 41.0; 31.4 % of new bone
Phase 2 N=18 Cell Therapy for Craniofacial Bone Defects
Cleft Palate · Trauma
Primary: Bone Regeneration — 1.5; 3.3 implant sites
N/A N=225 Incidence and Risk Factors for Surgical Site Infection After Intramedullary Nailing of Femoral and Tibial Fractures
Fracture Fixation, Intramedullary · Surgical Wound Infection
Primary: Incidence of Surgical Site Infection (SSI) Relating to Intramedullary Nailing for Fixation of Diaphyseal Femoral and Tibial Fractures — 26; 195 Participants
N/A N=142 BBOT: Bacterial Burden in Ortho Trauma Procedures
Orthopaedic Trauma Infections
Primary: Number of Participants With Tissue Samples Identified With Bacterial DNA According to Highly Sensitive Bacterial Assays — 10; 24; 20 Participants
N/A N=8 Case Series of New Alloplastic Bone Graft Material
Periodontology · Oral Surgery
Primary: Percentage Change in Radiographic Measurement of Alveolar Ridge Height — 1.2 percentage of change
Phase 4 N=17 Treatment of Post-Extraction Dehisced Socket - A Case Series Study
Tooth Loss
Primary: Bone Volumetric Reduction From Baseline to 20 Weeks Post-extraction — 73.26 mm3
Phase 3 N=26 Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
Alveolar Bone Loss · Tooth Loss
Primary: Overall Horizontal Change in Alveolar Ridge Width — -1.34; -2.21 Millimeters
Phase 2 N=29 Study to Assess Safety and Clinical Activity of Local MBN-101 in Treatment of Infected Bone Sites
Bacterial Infection
Primary: Number of Participants With Adverse Events — 5; 4; 1; 6 participants
N/A N=27 A Prospective Study: Alveolar Ridge Augmentation Using Tenting Screws, Acellular Dermal Matrix and Combination Particulate Grafts
Dental Alveolus · Oral Surgical Procedures, Preprosthetic
Primary: Gain in Horizontal Ridge Dimension — 3.33; 3.09 gain in ridge width (mm)
N/A N=39 Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
Tooth Loss
Primary: Number of Participants That Had an Implant That Survived 3 Years After Implant Placement — 3; 6; 7 participants
N/A N=41 Clinical and Radiographic Evaluation of Demineralized Freeze-Dried Bone Allograft Versus Platelet Rich Fibrin for the Treatment of Periodontal Intrabony Defects in Humans
Periodontitis
Primary: Change in Clinical Attachment Level (CAL) — 1.21; 1.03 mm
N/A N=66 Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 26.4; 24.5; 28.8 percentage of total area
N/A N=414 Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions
Foot Fusion
Primary: Subjects Fused at 24 Weeks (as Determined by CT Assessment) — 85; 159 Participants
N/A N=299 Augment® Injectable Bone Graft Compared to Autologous Bone Graft as a Bone Regeneration Device in Hindfoot Fusions
Degenerative Joint Disease · Congenital Deformity · Arthritis
Primary: Pain on Weight Bearing — 71.0; 70.7; 29.5; 28.2 units on a scale
N/A N=20 Incisional Vacuum Assisted Closure (IVAC) Device and Its Effect on Implanted Bone Morphogenic Protein (BMP-2)
Fractures, Closed
Primary: Presence of BMP-2 in Effluent Collected in IVAC Canister — 6; 11 participants — p==0.36
N/A N=43 Ridge Preservation Following Tooth Extraction Using Two Mineralized Cancellous Bone Allografts
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 27.19; 24.08 percentage
N/A N=11 Straumann Bone Ceramic Versus BioOss in Sinus Elevation
Jaw, Edentulous, Partially · Alveolar Bone Loss
Primary: Histologically Measured Bone to Implant Contact (BIC) — 64.552; 54.904 percentage of total surface
N/A N=150 The Effect of Bone-void Filler on Anterior Knee Pain Following ACL Reconstruction
ACL
Primary: Score on Knee Injury and Osteoarthritis Outcome Score (KOOS) Survey — 67; 69; 67.7 score on a scale
N/A N=17 Prospective Study of Thoracolumbar Spinal Fusion Graft
Lumbar Degenerative Disc Disease
Primary: Spinal Fusion Grade at 1 Year Via CT Scan — 1.67; 2.4 score on a scale