Phase 4 N=230 Treatment of Vitamin D Insufficiency
Vitamin D Deficiency
Primary: Intestinal Calcium Absorption — 0.200; 0.217; 0.183; 0.206 Total Fractional Calcium Absorption
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=19 Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
Osteoporosis · Osteopenia · Vitamin D Deficiency
Primary: Change in Intestinal Calcium Absorption From Baseline to One Month — 3 percent calcium absorption
N/A N=68 Improving Vitamin D Status in Home-bound Elders
Vitamin D Deficiency · Accidental Falls
Primary: Change in 25-hydroxyvitamin D Levels Over 5 Months — 21.7; 0 ng/mL
N/A N=36 Health Benefits of Vitamin D and Calcium in Women With PCOS (Polycystic Ovarian Syndrome)
Polycystic Ovarian Syndrome · Vitamin D Deficiency
Primary: Serum HbA1C at 3 Months — 5.55 percentage
Phase 4 N=29 Vitamin D Repletion in Stone Formers With Hypercalciuria
Nephrolithiasis · Urolithiasis · Idiopathic Hypercalciuria
Primary: Change in 24 Hour Urine Calcium — 2 mg/day
Phase 3 N=130 Vitamin D in Vulnerable Adults (VIVA-VA)
Frail Elderly · Vitamin d Deficiency
Primary: Change in Short Physical Performance Battery Test Score — 7.3; 7.0 units on a scale
N/A N=81 Optimizing Vitamin D in the Elderly
Deficiency of Vitamin D3
Primary: Total 25-OH Vitamin D3 Level — 33; 34; 43; 61 ng/mL — p=<.0001
Phase 2 N=92 Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
Glucose Intolerance · Type 2 Diabetes Mellitus · Metabolic Syndrome
Primary: Chang in Disposition Index, a Measure of Beta Cell Function — 287; 314; -122; -129 units on a scale
Phase 3 N=265 Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Vitamin D Deficiency · Pregnancy
Primary: 25-hydroxyvitamin D at Visit 7 — 36.7; 39.8 ng/mL
N/A N=37 Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
Obesity · Vitamin D Deficiency
Primary: Vitamin D Concentrations, Pre Operative and Post Bariatric Surgery Following 12 Weeks of Vitamin D Supplementation — 19.1; 27.2 ng/mL — p=< 0.001
Phase 2 N=41 Calcitriol, Physical Activity, and Bone Health in Cancer Survivors
Breast Neoplasms · Bone and Bones
Primary: Bone Resorption (Exercise) — 13.8; 14.7 nm BCE — p=0.86
N/A N=90 Vitamin D Replacement After Kidney Transplant
Kidney Transplantation · Vitamin D Deficiency
Primary: Compare Efficacy and Safety of Two Vitamin D Supplements of These Doses in Normalizing Vitamin D Concentrations. — 8; 29 ng/ml
N/A N=204 Vitamin D Levels in Frail Elderly Patients With a Hip Fracture
Hip Fracture · Vitamin D Deficiency
Primary: Number of Participants With Suboptimal and Optimal Levels of Vitamin D (Serum-25(OH)D) — 106; 42; 15; 41 Participants
Phase 2 N=167 High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART
HIV-1 Infection
Primary: The Percent Change From Baseline in Bone Mineral Density (BMD) at Total Hip — -1.46; -3.19 percentage change — p=0.001
N/A N=110 The Effect of Vitamin D and Exercise on Balance in Postmenopausal Women
Vitamin D Deficiency
Primary: Postural Stability Test (Biodex) Assessed at Baseline — 2.25; 2.30; 2.18; 1.97 score
Phase 1 N=157 Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
Healthy
Primary: Serum 25-hydroxyvitamin D — 26.7; 22.4 ng/mL — p=0.003
Phase 3 N=2,259 Vitamin D/Calcium Polyp Prevention Study
Colorectal Cancer · Polyps · Adenomas
Primary: Colorectal Adenomas — 48.2; 44.9; 47.0; 45.7 percentage of subjects
N/A N=9 Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption
Rheumatoid Arthritis · Crohn's Disease
Primary: Intestinal Absorption of Calcium
N/A N=19 Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery
Vitamin D Deficiency · Gastrointestinal Diseases
Primary: # of Pts w/ Enhanced Vitamin D Status — 3; 3 Participants
Phase 2 N=85 Vitamin D HIV Study on Postmenopausal Women
HIV
Primary: Change in Bone Mineral Density (BMD) — 0.4; -0.8 percentage change
N/A N=18 Enhancing Skeletal Adaptations to PTH and Exercise
Exercise · Bone Resorption · Bone Formation
Primary: Change in C-terminal Peptide of Type 1 Collagen (CTX) — 0.03; 0.03; 0.05; 0.03 ng/mL
N/A N=22 Impact of Vitamin D Supplementation on Lactation Associated Bone Loss
Osteoporosis
Primary: Change in Bone Mineral Density (BMD) in HIP at 6 Months — -0.041; 0.011 grams/cm^2
Phase 4 N=53 Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers
Obesity · Overweight
Primary: Change in Body Weight — -3.9; -3.5 kg — p=0.441
N/A N=96 Vitamin D Repletion in Coronary Artery Disease
Vitamin D Deficiency · Coronary Artery Disease · Endothelial Dysfunction
Primary: Endothelial Function — 0.13; -0.04 reactive hypermia index
Phase 2 N=5 Blood Pressure in Blacks and Calcium (BBC) and Vitamin D Study
Hypertension · Vitamin D Deficiency
Primary: Change in Mean Blood Pressure From Baseline to 12 Weeks — 4.3 mmHg
Phase 2 N=241 Adding Phosphorus to Osteoporosis Drug Treatment
Osteoporosis · Osteopenia
Primary: Lumbar Spine and Hip BMD, Measured as Grams Per Square Centimeter. — 0.76; 0.78; 0.88; 0.86 g/cm2
Phase 2 N=100 Vitamin D Deficiency, Muscle Pain, Joint Pain, and Joint Stiffness in Postmenopausal Women Receiving Letrozole For Stage I-III Breast Cancer
Arthralgia · Musculoskeletal Complications · Pain
Primary: Number of Early Breast Cancer Patients Prescribed Adjuvant Letrozole That Are Vitamin D Deficient and Who Experience Myalgias, Arthralgias and/or Joint Stiffness — 12; 1…
Phase 1 N=27 Effect of Calcium 500 mg and Vitamin D3 1000 IU Chewable Tablet on Intestinal Calcium Absorption
Healthy Volunteers
Primary: PTH AUC(0-6): Area Under the Serum Concentration-Time Curve From Time 0 to 6 Hours for Parathyroid Hormone — 215; 157 hour*picogram per milliliter (hr*pg/mL)
Phase 3 N=47 Calcium and Vitamin D to Optimize Bone Mass in Boys With Risperidone-induced Hyperprolactinemia
Risperidone-induced Hyperprolactinemia
Primary: Trabecular Bone Mineral Density in the Ultradistal Radius — 192.9; 197.2; 191.0; 194.6 mg/cm^3
N/A N=125 Vitamin D, Insulin Resistance, and Cardiovascular Disease
Vitamin D Deficiency · Insulin Resistance · Type 2 Diabetes Mellitus
Primary: Hypertension (24h Blood Pressure, Central Blood Pressure, and Office BP) — 126.6; 131.1; 79.2; 78.9 mm Hg