N/A N=9 Therapeutic Dance Intervention for Children With Cerebral Palsy
Cerebral Palsy
Primary: Congruent Trial (Hearts) Accuracy — 87.96; 87.50 percentage of correct
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=55 Quantifying Patient-Specific Changes in Neuromuscular Control in Cerebral Palsy
Cerebral Palsy
Primary: Change in Walk Dynamic Motor Control Index 6-months After Orthopaedic Surgery — -2.4 normalized z-score
Phase 1 N=11 Safety and Tolerability of Dalfampridine in Subjects With Cerebral Palsy
Cerebral Palsy (CP)
Primary: Safety and Tolerability of Dalfampridine-ER 10mg in Subjects With Cerebral Palsy (CP) — 1; 2; 6; 9 participants
N/A N=12 Cerebral Palsy: Short-burst Interval Training
Cerebral Palsy Spastic Diplegia
Primary: Change in Walking Performance High Versus Low Frequency SBLTT Groups — 1872; 1551 strides per day — p=.39
Phase 3 N=63 A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents
Cerebral Palsy, Dyskinetic
Primary: Change From Baseline in the Movement Disorder-Childhood Rating Scale (MD-CRS) Part II Total Score (Movement Disorder Severity, Centrally Read) at Week 15 — -0.4; -1.5…
N/A N=10 Precision Gait Retraining for Children With Cerebral Palsy
Cerebral Palsy · Gait Disorders, Neurologic
Primary: Gait Metric Accuracy — 2.01 percentage of error
Phase 2 N=20 Safety and Effectiveness of Banked Cord Blood or Bone Marrow Stem Cells in Children With Cerebral Palsy (CP).
Cerebral Palsy
Primary: Safety as Assessed by Number of Participants With In-hospital Infusion Toxicity — 0; 0; 0 Participants
N/A N=32 Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy
Cerebral Palsy Spastic Hemiplegic
Primary: Change From Baseline Pediatric Motor Activity Log (PMAL) Score at Post Test — 0.83; 0.00; 0.50; -0.05 score on a scale
N/A N=20 Perinatal Stroke: Understanding Brain Reorganization
Stroke · Hemiparesis
Primary: Cortical Excitability MEP Amplitude (µV) — 325 µV
N/A N=29 Effect of Botox and Vibration on Bone in Children With Cerebral Palsy
Cerebral Palsy · Muscle Spasticity
Primary: Bone Structure — 10.4; 7.6; 6.7; 9.0 percent change
Phase 2 N=91 A Study of UCB and MSCs in Children With CP: ACCeNT-CP
Cerebral Palsy
Primary: Change in Gross Motor Function Measure (GMFM-66) in Excess of Expected Change — 5.83; 4.27; 3.15 score on a scale
N/A N=43 Power Training Combined With Interval Treadmill Training
Cerebral Palsy · Central Nervous System Diseases · Brain Damage, Chronic
Primary: Change in Self-selected Gait Speed (Normalized) — -0.0010; 0.0163 dimensionless
N/A N=34 Quantifying Energetic Demands of Walking for People With Cerebral Palsy
Cerebral Palsy
Primary: Net Nondimensional Oxygen Cost — -34.13; -15.86; 1.07; -0.60 Percent change relative to baseline
Phase 3 N=370 Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy
Primary: Occurrence of Treatment Emergent Adverse Events (TEAEs) Overall and Per Injection Cycle — 53; 44; 26; 31 participants
N/A N=27 Effects of Pediatric Aquatic Therapy in Children With Spastic Cerebral Palsy
Spastic Cerebral Palsy
Primary: Unit on Gross Motor Function Measure Scale (GMFM) — 5.12; 2.00 units on a scale — p=0.007
Phase 3 N=311 Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy
Lower Limb Spasticity Due to Cerebral Palsy
Primary: Change From Baseline in the Ashworth Scale (AS) Score of Plantar Flexors of the Primary Body Side at Day 29 (Week 4) of the First Injection Cycle (1st IC) — -0.7; -0.66…
N/A N=40 Effect of Trunk Stabilization Exercises on Quality of Life and Communication in Cerebral Palsy
Cerebral Palsy
Primary: Visual Analogue Scale (VAS) — 6.75; 5.29 units on a scale
N/A N=44 A Pilot Study of Hand Function in Children With Cerebral Palsy Undergoing Intensive Neurophysiological Rehabilitation
Cerebral Palsy
Primary: Jebsen Taylor Hand Function Test for Dominant Hand — 130.1; 115.2 seconds
N/A N=20 Single-session tDCS in Cerebral Palsy
Cerebral Palsy · Perinatal Stroke · Periventricular Leukomalacia
Primary: Change in Motor Evoked Potential Amplitude — 12.4; 81.7; -34.4 percent change
N/A N=15 Use of Joystick-operated Ride-on-toys to Improve Affected Arm Use and Function in Children With Hemiplegic Cerebral Palsy
Hemiplegic Cerebral Palsy
Primary: Change in Affected Arm Movement Control — 74.9; 78.3; 83.8 percentage
N/A N=19 Muscle Synergies During Gait in Children With Cerebral Palsy Undergoing Robot-assisted Gait Therapy
Cerebral Palsy
Primary: Change in Cosine Similarity of the Muscle Synergies of the Most Affected Lower Limb — 2 percentage of muscle synergies
N/A N=41 Cerebral Palsy Early Mobility Training
Cerebral Palsy
Primary: Change in Gross Motor Function Measure (GMFM-66) During Treatment Phase — 2.2; 3.5 units on a scale
Phase 3 N=351 Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy
Cerebral Palsy · Spasticity
Primary: MP: Change From Baseline in Ashworth Scale (AS) in UL Primary Clinical Target Pattern at Week 4 — -0.93; -1.15; -0.96; -1.02 Unit on a scale — p== 0.017
N/A N=11 Physical and Social Benefits of Multi-Player Interactive Computer Play Games in Youth With Cerebral Palsy
Cerebral Palsy
Primary: Change in the 7.5 Meter Shuttle Run Test for Gross Motor Function Classification Scale (GMFCS) Level III (SRT-III) — 8.3; 8.6; 1.1; 0.7 units on a scale
N/A N=6 Use of Low Cost Prostheses to Improve Upper Extremity Function in Children With Cerebral Palsy
Cerebral Palsy · Prosthesis User
Primary: Number of Participants With Clinically Significant Increase in Assisting Hand Assessment (AHA) Score — 4 Participants
Phase 3 N=212 Efficacy And Safety Of Dysport In The Treatment Of Upper Limb Spasticity In Children
Upper Limb Spasticity (Altered Skeletal Muscle Performance) in Children
Primary: Mean Change From Baseline to TC 1, Week 6 in MAS Score in the TC 1 PTMG — -1.5; -1.9; -2.2 score on a scale — p=0.0118
N/A N=20 Brain Stimulation and Hand Training in Children With Hemiparesis
Pediatric Hemiparesis
Primary: Change in Assisting Hand Assessment (AHA) — 6.4; 8; 5.5; 7.6 score on a scale
N/A N=708 On Track: Monitoring Development of Children With Cerebral Palsy or Gross Motor Delay
Cerebral Palsy
Primary: Early Clinical Assessment of Balance (ECAB) — 79.4; 61.1; 38.0; 23.0 units on a scale
N/A N=47 Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy
Cerebral Palsy · Physical Activity · Attention Disorder
Primary: Change of Clinical Global Improvement(CGI) — -0.13; -0.09; 2.65; 3.87 score on a scale
N/A N=15 Contralaterally Controlled FES for Hand Opening in Hemiplegic Cerebral Palsy
Cerebral Palsy
Primary: Change in Assisting Hands Assessment Logit Score at End of Treatment — 2.63; 4.33 Scores on a scale