N/A N=53 Multifactorial Approach to Emergent Cerclage
Cervical Insufficiency
Primary: Gestational Latency Achieved Between Cerclage Placement and Time of Delivery — 80; 97 days — p=0.018
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Cervix Monitor for Elasticity and Length Measurements
Preterm Birth
Primary: Cervix Elasticity — 54; 19.7 kPa
N/A N=385 Prevention of Preterm Birth Using Cervical Pessary in Pregnant Women With Short Cervix
Preterm Birth
Primary: Spontaneous Delivery Before 34 Completed Weeks — 51; 12 Participants
N/A N=230 Cervical Ripening in Premature Rupture of Membranes
Pregnancy · Premature Rupture of Membranes · Preterm Premature Rupture of Membranes
Primary: Rate of Cesarean Section — 27; 26; 89; 86 participants — p=0.99
Phase 3 N=465 PREGNANT Short Cervix Trial
Preterm Delivery · Short Cervix · Short Uterine Cervical Length
Primary: Number of Participants With Birth <=32 6/7 Weeks Gestation. — 36; 21 participants — p=0.020
Phase 4 N=236 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obesity · Labor Induction · Cesarean Delivery
Primary: Number of Participants With a Need for Cesarean Delivery — 51; 53 Participants
N/A N=80 Modifying Cervical Bishop Scoring System
Failed Induction of Labor
Primary: Area Under Receiver Operating Characteristic Curve (ROC) for Modified Bishop Score — 0.916 probability — p=0.000
Phase 2 N=271 Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
Preterm Birth
Primary: Number of Participants Not Giving Birth Before Week 32 and Week 34 of Gestation — 73; 71; 67; 66 Participants
N/A N=102 Comparison of Pre-Induction Cervical Ripening
Failed Labour
Primary: Vaginal Delivery — 20; 21; 20 participants
N/A N=2,227 Foley Bulb With Oral Misoprostol for Induction of Labor
Pregnancy · Labor, Induced
Primary: Number of Participants With Vaginal Delivery — 869; 860 Participants — p=0.86
N/A N=122 Prevention of Preterm Birth With a Pessary in Singleton Gestations
Preterm Birth · Short Cervix
Primary: Number of Subjects Experiencing Preterm Birth — 26; 23 Participants
N/A N=50 Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon
Induction of Labor
Primary: Rate of Induction To Delivery — 732.19; 944.35 minutes — p=0.037
N/A N=123 Cervical Foley Plus Vaginal Misoprostol for Labor Induction
Induction of Labor
Primary: Time From Start of Labor Induction to Vaginal Delivery — 15.3; 18.3 hour — p=0.03
N/A N=197 Foley Bulb Traction for Cervical Ripening
Cervical Ripening · Induction of Labor
Primary: Time to Delivery — 19.8; 18.8 hours
Phase 3 N=1,311 A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix
Short Cervical Length
Primary: Number of Participants With Delivery or Fetal Loss of Either Twin Prior to 35 Weeks Gestation — 84; 84; 86 Participants
N/A N=293 Single Balloon Catheter Compared With Double Balloon Catheter for Ripening of the Unfavorable Cervix
Induction of Labor
Primary: Average Time in Hours From Insertion of the Catheter Until Delivery — 19.4; 19.1 HOURS
N/A N=376 Foley Catheter Versus Cervidil for Induction of Labor at Term
Labor Induction
Primary: Time Of Start Of Induction Of Labor To Delivery — 21.6; 26.6 hours
N/A N=46 Prevention of Preterm Birth With a Pessary in Twin Gestations
Premature Birth · Short Cervix
Primary: Number of Participants With Preterm Delivery — 9; 8 Participants
N/A N=80 Cook Balloon vs Dilapan-S for Outpatient Cervical Ripening
Induced; Birth
Primary: Change in Bishop Score — 3.0; 3.0 score on a scale — p=0.91
N/A N=100 Foley Catheter Compared to the Foley Catheter Alone for Cervical Ripening
Cervical Ripening · Induction of Labor
Primary: The Median Times From Placement of Foley Catheter to Vaginal Delivery — 21.2; 31.3; 17.1; 14.8 hours
N/A N=200 Cervical Length and Bishop Score in Preinduction Cervical Assessment Prior to Induction of Labor
Cervical Dystocia
Primary: Cervical Length Prior to Labor Induction — 2.9; 3 centimetres
Phase 3 N=1,308 Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor
Cervical Ripening · Labor, Induced
Primary: Minutes From Drug Insertion to Vaginal Delivery — 1595.5; 2127; 1649.5 minutes — p=0.974
Phase 3 N=180 Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin
Cervical Ripening · Induction of Labor · Multiparity
Primary: Time From Cervical Ripening to Delivery — 16.88; 13.13 hours
N/A N=144 Balloon Catheter for Cervical Ripening
Cervical Dilation
Primary: Duration — 16.2; 16.9 hours — p=0.814
N/A N=251 Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption
Placenta, Retained · Postpartum Hemorrhage
Primary: Placental Retention Rate — 26; 8; 24 participants — p=0.05
N/A N=135 Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester Abortion
Medical; Abortion, Fetus
Primary: Cervicovaginal Fetal Fibronectin Level — 39.4 nanogram per milliliter
N/A N=300 Cervical Preparation Before Dilation and Evacuation
Abortion, Induced
Primary: Operative Time — 6.27; 6.28; 5.53 minutes
N/A N=89 Paracervical Versus Intracervical Lidocaine
Abortion, Induced · Pain
Primary: Pain Score, as Assessed Using a 10 cm Linear Visual Analog Scale (VAS) — 4.25; 3.97 units on a scale
Phase 4 N=108 Pitocin or Oral Misoprostol for PROM IOL
PROM
Primary: Time From Induction of Labor (IOL) to Delivery — 18.1; 14.9 Hours
N/A N=129 Outpatient Foley For Starting Induction of Labor at TErm
Pregnancy
Primary: Total Time From Admission to Delivery — 13.5; 12.4 hours — p=0.38