N/A N=230 Cervical Ripening in Premature Rupture of Membranes
Pregnancy · Premature Rupture of Membranes · Preterm Premature Rupture of Membranes
Primary: Rate of Cesarean Section — 27; 26; 89; 86 participants — p=0.99
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=300 Cervical Preparation Before Dilation and Evacuation
Abortion, Induced
Primary: Operative Time — 6.27; 6.28; 5.53 minutes
N/A N=20 Cervix Monitor for Elasticity and Length Measurements
Preterm Birth
Primary: Cervix Elasticity — 54; 19.7 kPa
Phase 2 N=51 Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy
Cervical Priming
Primary: Change in Diameter of the Internal Cervical os From Baseline (Pre-treatment) to Just Prior to the Hysteroscopy Procedure (Post-treatment). — 2.2; 2.3; 1.5 mm
Phase 4 N=5 Regulation of Cervical Mucus Secretion
Fertility · Contraception
Primary: Median Cervical Mucus Score - Baseline — 11; 13 score on a scale
N/A N=50 Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
Abortion, Induced
Primary: Procedure Time — 10.9; 11.8 minutes
N/A N=50 Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Abortion
Primary: Time for Completion of Procedure — 8.0; 9.87 Minutes — p=0.05
N/A N=80 Modifying Cervical Bishop Scoring System
Failed Induction of Labor
Primary: Area Under Receiver Operating Characteristic Curve (ROC) for Modified Bishop Score — 0.916 probability — p=0.000
Phase 4 N=236 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obesity · Labor Induction · Cesarean Delivery
Primary: Number of Participants With a Need for Cesarean Delivery — 51; 53 Participants
Phase 3 N=465 PREGNANT Short Cervix Trial
Preterm Delivery · Short Cervix · Short Uterine Cervical Length
Primary: Number of Participants With Birth <=32 6/7 Weeks Gestation. — 36; 21 participants — p=0.020
N/A N=102 Comparison of Pre-Induction Cervical Ripening
Failed Labour
Primary: Vaginal Delivery — 20; 21; 20 participants
Phase 3 N=50 Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks
Cervical Preparation
Primary: Length of Procedure — 14; 13.5 minutes
N/A N=144 Balloon Catheter for Cervical Ripening
Cervical Dilation
Primary: Duration — 16.2; 16.9 hours — p=0.814
Phase 4 N=70 24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
Abortion, Second Trimester
Primary: Procedure Time — 9.5; 9.9 minutes
N/A N=32 Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
Abortion, Second Trimester
Primary: Procedure Time — 22.4; 22.6 minutes
N/A N=41 Paracervical Block for Pain Associated With Laminaria Insertion
Pain
Primary: Pain After Placement of Laminaria (100 mm Visual Analog Scale) — 13; 54 units on a scale (100 mm VAS) — p=0.01
N/A N=100 Foley Catheter Compared to the Foley Catheter Alone for Cervical Ripening
Cervical Ripening · Induction of Labor
Primary: The Median Times From Placement of Foley Catheter to Vaginal Delivery — 21.2; 31.3; 17.1; 14.8 hours
Phase 4 N=15 Effect of hCG on Receptivity of the Human Endometrium
Infertility · Subfertility
Primary: Endometrial Staging in hCG Versus Vehicle Treated Patients — 4.0; 4.6; 3.9; 6.5 days — p=<0.05
N/A N=150 Sweeping the Membranes, Cervical Length and Duration of Labor
Disorder of Amniotic Cavity and/or Membrane
Primary: Cervical Shortening — 27.45; 29.61; 23.30; 23.88 millimeters
N/A N=50 Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon
Induction of Labor
Primary: Rate of Induction To Delivery — 732.19; 944.35 minutes — p=0.037
Phase 2 N=348 Effect of Tafoxiparin on Cervical Ripening and Induction of Labor in Term Pregnant Women With an Unripe Cervix
Labor Onset and Length Abnormalities
Primary: Cervical Ripening Rate, Measured by Bishop Score - Slope — 0.86; 0.81; 0.78; 0.62 Slope (Bishop Score/day)
Phase 2 N=271 Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
Preterm Birth
Primary: Number of Participants Not Giving Birth Before Week 32 and Week 34 of Gestation — 73; 71; 67; 66 Participants
Phase 4 N=96 12 Versus 20 mL PCB for D&E Cervical Prep
Pain
Primary: Pain Immediately Following Dilator Insertion — 41; 49 score on a scale
N/A N=53 Multifactorial Approach to Emergent Cerclage
Cervical Insufficiency
Primary: Gestational Latency Achieved Between Cerclage Placement and Time of Delivery — 80; 97 days — p=0.018
Phase 2 N=18 CerviPrep for Applying Topical Gemcitabine to the Cervix in Treating Patients With Primary Endometrial, Cervical, or Ovarian Epithelial Cancer
Cervical Cancer · Endometrial Cancer · Ovarian Cancer
Primary: Number of Patients With Measurable Concentration of Gemcitabine in Uterine Vein (dFdC) — 5 Participants
N/A N=123 Cervical Foley Plus Vaginal Misoprostol for Labor Induction
Induction of Labor
Primary: Time From Start of Labor Induction to Vaginal Delivery — 15.3; 18.3 hour — p=0.03
Phase 4 N=100 Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
Induced Abortion
Primary: Initial Cervical Dilation — 11.7; 10.9 mm
N/A N=125 Misoprostol Versus Dilapan-S for Cervical Preparation
Cervical Ripening
Primary: Cervical Dilation in Women Following Exposure to Either Ripening Agent — 32.1; 33.9 mm
N/A N=376 Foley Catheter Versus Cervidil for Induction of Labor at Term
Labor Induction
Primary: Time Of Start Of Induction Of Labor To Delivery — 21.6; 26.6 hours
N/A N=73 Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
Contraception
Primary: Provider Perceived Ease of Insertion on a 100 Point Visual Analogue Scale — 21; 21 units on a scale