N/A N=21 Magnetic Resonance Imaging (MRI) of Appendicitis in Children
Appendicitis
Primary: Diagnostic Sensitivity/Specificity and Accuracy of Appendiceal MRI Comparedsurgical Findings or Clinical Follow-up — 13; 17; 4; 19 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=73 Rapid MRI for Acute Pediatric Head Trauma
Head Trauma · Image, Body
Primary: Sensitivity: Percentage of MRIs Correctly Identifying Clinically Important Intracranial Injury (True Positives) — 70 Percentage of MRIs correctly identifying
Phase 1 N=140 A Study of Magnetic Resonance Imaging (MRI) With Gadavist in Children
Magnetic Resonance Imaging
Primary: Plasma Clearance Estimates of Gadobutrol by Age Group — 2.07; 3.28; 4.90; 3.24 L/h
N/A N=120 Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia
Children Requiring MRI
Primary: Change in Body Temperature in Children Undergoing MRI Under General Anesthesia (GA)and Change in Room Temperature Before and After MRI — 36.7; 36.3; -0.4; 21.1 celsius…
N/A N=45 MRI for Non-Invasive Imaging in Neonates and Children
Healthy · Cystic Fibrosis (CF) · Asthma
Primary: Ventilation Defects as Seen on Hyperpolarized Helium-3 MRI — 9; 13; 16 Participants
N/A N=657 Clinical Use of a New Neonatal MRI System
Magnetic Resonance Imaging
Primary: Number of Participants With Adverse Events as Observed During and After Scanning. — 4 Participants
N/A N=12 MRI for Non-invasive Evaluation of Brain Stress
Craniosynostosis
Primary: Blood Flow and Perfusion — 26.8 ml/min/100g — p=0.004
N/A N=386 Clinical Use of a Neonatal MRI System
NICU MRI
Primary: Number of Participants With Adverse Events as Observed During and After Scanning. — 0 Participants
Phase 3 N=20 Contrast-enhanced MRI in Children 2 Months to <2 Years
Magnetic Resonance Imaging
Primary: Number of Participants With Diagnostic Adequacy - Open-label Clinical Investigators (Per Protocol Set) — 1; 0; 2; 3 Participants
Phase 4 N=40 Dexmedetomidine and Propofol for Pediatric MRI Sedation
Headache · Tumor · Seizure Disorder
Primary: Efficiency of Propofol Dexmedetomidine Sedation Compared With Propofol Infusion — 98; 77 minutes
N/A N=52 Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.
Liver Neoplasms · Adenoma · Carcinoma
Primary: Percentage of Participants With Overall Change in Additional Diagnostic Information Obtained When Comparing the Combined Precontrast/Postcontrast Images With the…
Phase 4 N=17 Feraheme As An MRI Contrast Agent For Pediatric Congenital Heart Disease
Pediatric Congenital Heart Disease
Primary: Composite Image Quality Score Among 7 Anatomical Structures. — 3.9; 2.7 score on a scale
Phase 1 N=44 Gadobutrol Pharmacokinetic and Safety Study in Pediatric Subjects Aged <2 Years (Term Newborn Infants to Toddlers 23 Months of Age Inclusive)
Magnetic Resonance Imaging
Primary: Area Under the Plasma Concentration Versus Time Curve (AUC) From Time 0 to Infinity of Gadobutrol: Individual — 776 micromole*h/L
N/A N=15 Pilot Study: Safety of a Customized MRI System for Neonatal Imaging
Safety of a Customized NICU MRI System
Primary: Number of Participants With Adverse Events as Measured by Vital Signs, Change in Temperature, and Physical Exam — 0 Adverse Events
N/A N=49 Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit (Firefly Sheffield)
Neonatal Neuroimaging
Primary: Image Diagnostic Quality for Phase 1 — 24 Participants
N/A N=12 Comparing MRI to CT on Pediatric Craniosynostosis.
Craniosynostosis
Primary: Number of Participants With 90% or Greater Concordance Between ZTE and CT Imaging Diagnosis — 9 Participants
N/A N=134 Pediatric Catheter-related Thrombosis Imaging Study
Thrombosis
Primary: Total Number of Participants Who Completed the Study-Related Ultrasound (US) and Magnetic Resonance Imaging (MRI) With and Without Contrast — 133; 113; 113; 110…
Early Phase 1 N=14 DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors
Childhood Brain Neoplasm · Recurrent Childhood Brain Neoplasm
Primary: Vascular Properties of Pediatric Brain Tumors Using Dynamic Susceptibility-weighted Contrast Enhanced MRI (DSC-MRI) After Administration of Ferumoxytol — .93 mL/g
N/A N=13 PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer
Childhood Cancer
Primary: Diagnostic Accuracy of PET/MRI
Phase 4 N=51 DOTAREM Pharmacokinetics and Safety Study in Pediatric Subjects Aged < 2 Years
Magnetic Resonance Imaging
Primary: Area Under the Curve of DOTAREM in Plasma — 1591.1 hour.µmol/L
N/A N=1,509 Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices
Arrhythmias, Cardiac
Primary: Device Malfunction — 24; 52 Participants
N/A N=63 China 3T MRI Study
Bradycardia · Tachycardia · Heart Failure
Primary: The Occurrence of an MRI-related Event for CIED — 59; 0 Participants — p=0.002
N/A N=89 Virtual Reality Preparation for Medical Imaging
Virtual Reality · Paediatrics · Radiology
Primary: Percentage of Participants With Success — 9; 14; 12 Participants
Phase 2 N=80 Pharmacokinetics, Safety and Efficacy of P03277 in Pediatric Patients Undergoing Central Nervous System Contrast-enhanced MRI
Central Nervous System Indication · Pediatric Patients · Body Indication
Primary: Elimination Half-life — 1.29; 1.48; 1.77 hours
N/A N=101 Normal Liver Stiffness by MR Elastography
Liver Diseases
Primary: Liver Stiffness — 2.1 kPa
Phase 2 N=57 Study to Find the Appropriate Dose of a New Gadolinium-based Contrast Agent (GBCA) for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditions
Central Nervous System Pathology
Primary: Overall Diagnostic Preference — 10; 34; 56; 26 Percentage of participants — p=<0.0001
Phase 4 N=71 A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
Epilepsy · Cerebral Palsy · Developmental Delay
Primary: Dosage/Consumption — 0.36; 0.25 mcg/kg/min
N/A N=10 Transcranial Magnetic Stimulation for Children With Tourette's Syndrome
Tourette Syndrome
Primary: Yale Global Tic Severity Scale — 64.40; 26.40 units on a scale
Phase 4 N=74 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Apnea of Prematurity · Intraventricular Hemorrhage · Brain Injury
Primary: White Matter Microstructural Maturation — 1.43; 1.42 apparent diffusion coefficient
Phase 4 N=615 Screening Contrast-Enhanced Mammography as an Alternative to MRI
Breast Cancer
Primary: Cancer Detection Rate (CDR) Per 1,000 Screenings — 8.3; 18.3 CDR per 1,000 screenings