Clinical Trial Search

Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05

Primary: Patient and Observer Scar Assessment Scale (POSAS) - PI Assessment — 4.4; 4.5 score on a scale

Primary: Visual Analogue Scale (VAS) — 2.90; 3.29 score on a scale

Primary: Cosmetic Outcome — 7.4; 6.6; 6.3; 6.00 score on a scale

Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale

Primary: Visual Analog Scale (VAS) — 7.47; 7.97 units on a scale

Primary: Mean Change From Baseline in Erythema — -1.687; 5.730 units on a scale

Primary: Photography- Independent Scar Assessment Panel

Primary: Subjective Cosmetic Result — 13; 26.5 units on a scale

Primary: Expert Panel Scar Assessment Score at Week 12: Part B — 37.8; 42.1 millimeter — p=0.168

Primary: Number of Partecipants With Improvement of Acne Scars and Marks and Without New Acne Scars After 4 Weeks — 5 participants

Primary: Expert Panel Scar Assessment Score at Week 12 — 36.6; 51.4 millimeter — p=<0.001

Primary: Change From Baseline in Vancouver Scar Scale Score(VSS) at 3 Months — -3.80; -2.61 units on a scale

Primary: Physician Observer Scar Assessment Score at Week 24 — 0.0; -0.5; 0.8; -0.3 units on a scale — p=1.000

Primary: Physician Global Assessment Using Physician Overall Opinion Question of Patient and Observer Scar Assessment Scale (POSAS) — 4.00; 4.68; 4.61; 4.86 units on scale…

Primary: Part B: Expert Panel Scar Assessment Score — -3.16; 0.18; 1.45; 2.91 millimeters

Primary: Healing Time — 78; 61 Days — p=0.094

Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale

Primary: Scar Evaluation at End of Treatment Period Comparing Treated to Standard of Care (Control) — 18.64; 50.52 score on a scale

Primary: Change in Patient and Observer Scar Assessment Scale (POSAS) Score From Baseline to Final Visit — -20; -20.6 score on a scale

Primary: Assessment of Visual Analog Scale (VAS) Change (Values From 0 (Worst) to 10 (Best)) — 0; 50 Percentage reporting improvement

Primary: Visual Analogue Scale (VAS) — 3.78; 5.58 Units on a scale

Primary: Overall Closure Time — 78; 216 seconds — p=<0.001

Primary: Number of Participants With Wound Closure — 8 participants

Primary: The Measured Difference in POSAS and VAS Scores Between 7-day and 10-day Groups — 12.9; 16.1; 19.5; 20.3 score on a scale

Primary: Improvement of Surgical Scars at 12 Months Compared to Baseline (Pre-treatment) as Evaluated by 3 Independent Blinded Reviewers Using the General Aesthetic Improvement…

Primary: Patient Observer Scar Assessment Scale (POSAS) — 17.69; 11.2; 15.2; 11.4 units on a scale — p=0.019

Primary: Change in Scar Pliability Between the Treated and Control Incision Sites as Measured by Skin Elasticity at 6 Months Compared to Baseline

Primary: Number of Participants With a Histologic Change in a Tissue Specimen That Was Injected With CCH — 2; 1; 1; 2 Participants

Primary: Cosmetic Outcome- Fraction Improving by at Least 1 Point Increase in Overall Appearance of Stretch Marks — 3; 5 Participants