N/A N=301 Dose the Saline Reduce the Mucus Production When Water Exchange Colonoscopy is Used?
Colon Mucous · Colonoscopy
Primary: Left Colon Mucus Score — 0.2; 1.4; 0.5; 0.7 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=40 Lubiprostone and Mucus Secretion in Patients With Chronic Constipation
Constipation
Primary: Change of Mucus and Mucin Secretion in Patients With Chronic Constipation and in Controls. — 260; 133; 229; 161 mg/hour
N/A N=32 Assessment of Colonic Epithelial Integrity With Mucosal Impedance
Inflammatory Bowel Diseases
Primary: Mucosal Impedance Values — 1139; 849; 891; 783 ohms
Phase 2 N=114 Colon Staining Efficacy of Single Oral Doses of Methylene Blue MMX
Colon Staining in Preparation for Colonoscopy
Primary: Evaluation of Mucosal Staining Efficacy — 6.8; 2.3; 8.1; 7.0 scores on a scale
N/A N=10 Evaluation of the Performance of the CleanC System-Israel
Colorectal Cancer (CRC) Screening
Primary: Percentage Subjects With Post Procedure Cleansing Level as Measured by the Boston Bowel Preparation Scale (BBPS) Adequate Cleansing-(BBPS>1 ) — 88.9 percentage of…
Phase 4 N=60 Lubiprostone, Colonic Motility and Sensation
Healthy
Primary: Colonic Compliance — 16.60; 16.50 mm Hg
Phase 2 N=46 Study of the MUC1 Peptide-Poly-ICLC Adjuvant Vaccine in Individuals With Advanced Colorectal Adenoma
Risk for Colorectal Cancer
Primary: Number of Participants With Anti Muc-1 Antibody — 39 participants
N/A N=71 Evaluation of the Motus Gl CleanUp System During Screening Colonoscopy
CRC
Primary: Mean Score of Boston Bowel Preparation Scale (BBPS) Index Prior and After the Use of MotusGI CleanUp System — 2.9; 2.9 units on a scale
Phase 4 N=360 Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
Spinal Cord Injury
Primary: Quality of Bowel Preparation — 3.4; 2.5; 3.6; 7.4 units on a scale
N/A N=5 Visualization of the Colon Through Use of the Magnetic Flexible Endoscope (MFE)
Colonoscopy
Primary: MFE Navigation to the Cecum From the Rectum in Less Than 40 Minutes — 0 Participants
N/A N=15 Evaluation of the Motus GI CleanUp System During Screening Colonoscopy
CRC
Primary: Mean of All Subjects Colon Segments BBPS>=2 — 3 Mean of BBPS score per segment
N/A N=8 Technical Feasibility Evaluation of Mucosal Staining During Colon Capsule Endoscopy (CCE) Procedure in Colorectal Cancer (CRC) High Risk Population, When Using MB-MMX
Colorectal Cancer · Polyp, Colonic
Primary: The Percent of Colonic Polyps Which Have a Visible Contrast to the Healthy Colonic Mucosa During Colon Capsule Endoscopy (CCE) — 58.3; 66.7; 0; 0 percentage of polyps…
Phase 2 N=53 Neoplasia Detection With Methylene Blue MMX Tablets in Patients With UC Undergoing Colonoscopy
Ulcerative Colitis
Primary: Detected Intraepithelial Neoplasia — 0.2 Number of detected IN
Phase 3 N=1,249 The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy
Colorectal Cancer
Primary: To Assess the Detection Efficacy of Chromoendoscopy Performed With 200mg Methylene Blue MMX® 25 mg Tablets Versus Placebo Tablets (White Light Endoscopy) in Terms of the…
Phase 2 N=147 Yoga and Bolus Lukewarm Saline as Rapid Colonoscopy Preparation
Colonic Neoplasms
Primary: Efficacy of Large Bowel Cleansing as Assessed by the Physician Performing the Colonoscopy — 18.69; 20.1 Score
N/A N=11 Effect of Seminal Fluid on the Colon Wall; Implications for HIV Transmission
Human Immunodeficiency Virus (HIV)
Primary: Epithelial Disruption Graded by a Pathologist Blinded to Study Intervention. — 1.0; 1.17 units on a scale — p=<0.05
Phase 4 N=158 Amitiza® Plus GoLYTELY® (PEG) Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy Preparation
Colonoscopy
Primary: Endoscopist Evaluation of Colon Cleanliness in the Lubiprostone Group vs the Placebo Group — 1.38; 1.24 score on a scale — p=0.05
N/A N=10 Clinical Investigational Plan: Evaluation of the Performance of the Motus Cleansing System
CRC
Primary: Number of Participants With Boston Bowel Preparation Scale( BBPS) >1 in All Colon Segments After the Use of MCS — 9 Participants
N/A N=229 Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique
Colonoscopy · Digestive System · Endoscopy
Primary: Colonoscopy Success With Minimal Sedation — 57; 32 Participants
Phase 3 N=135 Effects of Adalimumab on Mucosal Healing in Subjects With Crohn's Disease Involving the Colon
Crohn's Disease
Primary: Number of Subjects Without Mucosal Ulceration at Week 12 — 8; 17 Subjects — p=0.056
Phase 4 N=425 A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy
Colonoscopy
Primary: The Cleanliness of the Prep as Measured by the Ottawa Scale — 6.3; 6.8; 6.9; 5.1 Ottawa Scale
N/A N=100 Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
Polyps
Primary: Number of Adenomas — 83; 89; 28; 44 First Colonoscopy number of adenomas
N/A N=7 A Colonic Tube to Improve Bowel Function in Spinal Cord Injury
Constipation · Fecal Incontinence · Spinal Cord Injury
Primary: Change in Bowel QoL — -4.17; -3.65 units on a scale
N/A N=2 Stimulation for Colonic Motility
Neurogenic Bowel Dysfunction
Primary: Compare Changes in Number of Interventions Used to Complete Bowel Routine, Including Electrical Rectal Stimulation (Treatment) Versus Mechanical Rectal Distension…
N/A N=99 Laparoscopic Complete Mesocolic Excision on Colon Cancer
Operation Finding · Complications · Pathology
Primary: Histopathological Outcomes Obtained Through the Surgeries — 20.3; 19.2 nodes
N/A N=16 Diet Induced Intestinal Mucosal Adaptation
Healthy Conditions
Primary: Mucosal Surface Enlargement — 10.2; 9.9 percentage of muscular mucosae — p=<0.05
N/A N=230 Warm Water for Unsedated Colonoscopy
Colonoscopy
Primary: Number of Patients Undergoing Complete Unsedated Colonoscopy — 101; 89 participants
Phase 3 N=332 PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon
Colonic Diseases
Primary: Number of Participants With Successful Capsule Endoscopies or Standard Colonoscopies — 322; 326 participants
N/A N=262 Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
Right Colon Adenoma Miss Rate · Right Colon Hyperplastic Polyp Miss Rate
Primary: Percentage of Adenomas and Hyperplastic Polyps Missed During Initial Right Colon Examination — 18.0; 36.7 percentage of all missed polyps
Phase 4 N=520 MoviPrep® Versus GoLYTELY® Bowel Preparation in Hospitalized Patients Undergoing Colonoscopy
Bowel Preparation Before Colonoscopy
Primary: Number of Participants With Adequate Bowel Preparation — 111; 111 Participants — p=0.007