N/A N=269 Complete Histologic Resection of Adenomatous Polyps?
Adenomatous Polyps
Primary: Percent of Incompletely Resected Adenomatous Polyps — 10.1 percentage of incomplete resection
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=35 Anthocyanin Extract and Phospholipid Curcumin in Colorectal Adenoma
Colorectal Adenoma · Risk Reduction
Primary: Change in Beta Catenin Expression — 100; 100; 100; 100 percentage of positive cells
N/A N=44 Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis
Primary: Number of Polyps — 18.6; 22.6 Number of Polyps
Phase 2 N=46 Study of the MUC1 Peptide-Poly-ICLC Adjuvant Vaccine in Individuals With Advanced Colorectal Adenoma
Risk for Colorectal Cancer
Primary: Number of Participants With Anti Muc-1 Antibody — 39 participants
N/A N=928 Safety of Endoscopic Resection of Large Colorectal Polyps: A Randomized Trial.
Colon Polyps
Primary: Number of Participants With Delayed Bleeding Complications — 16; 33 Participants
N/A N=386 Efficacy of Segmental Examination Twice of the Proximal Colon on Adenoma Detection
Colonic Polyps
Primary: Difference of Adenoma Detection Rate in the Proximal Colon Among 2 Group. — 0.236; 0.331 proportion of participants
N/A N=1,148 Does Cap Assisted Colonoscopy Improve Detection of Adenomatous Polyps? (CAP Trial)
Adenomatous Polyps
Primary: Mean Number of Adenomas — 0.82; 0.89 adenoma per patient
Phase 2 N=44 Curcumin in Treating Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis
Primary: Polyp Number — 22.6; 18.6 polyps — p=0.58
N/A N=740 I-scan for Adenoma Detection
Colorectal Adenomatous Polyps
Primary: Number of Participants With Conventional Adenoma and Sessile Serrated Adenoma/Polyp Detected — 208; 171 Participants
N/A N=14,263 Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study
Colorectal Cancer · Advanced Adenocarcinoma · Serrated Polyp
Primary: ColoSense Sensitivity for Colorectal Cancer (CRC) — 25; 2 Participants
Phase 2 N=45 Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI
Adenomatous Polyp · Colorectal Cancer · Obesity
Primary: Change in Activated S6serine235 (i.e., the Ratio of pS6serine235/S6serine235) — 0.0228 weighted ratio of staining cells — p=> 0.773
N/A N=2,379 Colorectal Polyp Clinical Decision Support Device Study
Polyp · Colorectal · Colonoscopy
Primary: Specificity and Sensitivity CDSD-unaided and CDSD-aided Endoscopist Predictions of Diminutive Polyp Histology — 90.8; 90.7; 64.7; 59.5 percentage of polyps
N/A N=126 Comparison of Colon Adenoma Detection Rate Using Two Distal Colonoscope Attachments
Colon Cancer Screening · Colon Polyps · Colon Adenomas
Primary: Adenoma Detection Rate — 52.4; 40.5; 54.8 percentage of adenomas detected
Phase 2 N=112 Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis
Colorectal Cancer · Familial Adenomatous Polyposis
Primary: Percent Change in the Number of Polyps Greater Than or Equal to 2mm in Diameter in Focal Area(s) of the Colorectum — -1; -11; -1; -13 percentage change in polyp count
N/A N=384 Post-resection Treatment of Large Colon Polyps
Recurrence
Primary: Recurrence — 10; 5; 24 Polyps
Phase 4 N=480 Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Colorectal Neoplasms
Primary: Number of Participants With Detected Proximal Diminutive (<10 mm) Adenoma Detection Rate — 86; 89; 83; 38 participants
Phase 2 N=40 Evaluation of Surgically Resected Colorectal Adenomas and Carcinomas After 7 Days Pretreatment With Celecoxib
Colorectal Adenoma · Colorectal Carcinoma
Primary: Number of Subjects Witha Change (IMPROVEMENT) in Colo-rectal Adenocarcinoma as Measured by Cyclooxygenase-2 Activity After 7 Days of Celecoxib — 2.0; 2.0 Participant
N/A N=2 Optical Frequency Domain Imaging for Assessing Colonic Polyps
Colonic Polyps
Primary: Feasibility and Sensitivity of OFDI Imaging in the Colon — 2; 1 Participants
N/A N=194 Adenoma Detection Rate With a New Pediatric Colonoscope With a Short Turn Radius (Pentax Retroview) Compared With a Standard Pentax Pediatric Colonoscope
Colonoscopy
Primary: Percentage of Patients With At Least One Adenoma — 63; 68 Participants
N/A N=362 Hot Snare Versus Hot Snare Polypectomy With Saline Injection for Colorectal Polyps
Polyp of Large Intestine
Primary: Complete Resection Rate — 161; 148; 6; 7 Participants — p=0.05
N/A N=250 Precision-Based Magnesium Trial
Colorectal Cancer
Primary: TRPM7 Expression Level in Colorectal Mucosa by Mg Treatment Compared With Placebo — 0.03; 0.08; -0.09; -0.11 log (arbitrary units) — p=>0.05
N/A N=1,262 A 4-arm Clinical Trial of Fuse®, EndoCuff™, EndoRings™ and Standard Colonoscopy
Colorectal Neoplasms
Primary: Adenomas Per Colonoscopy — 1.53; 1.82; 1.55; 1.30 Adenomas per Colonoscopy
Phase 3 N=375 Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps
Precancerous Condition
Primary: Detection of Any Adenoma at the End of the Study — 17; 53; 121; 76 participants
N/A N=40 Hybrid APC Assisted EMR for Large Colon Polyps
Colon Polyp · Colon Adenoma · Colon Cancer
Primary: Percentage of Participants Having Complete Resection — 40 Participants
Phase 3 N=2,259 Vitamin D/Calcium Polyp Prevention Study
Colorectal Cancer · Polyps · Adenomas
Primary: Colorectal Adenomas — 48.2; 44.9; 47.0; 45.7 percentage of subjects
N/A N=84 High Definition Endoscopy With i-Scan for Small Colonic Polyp Evaluation: The HiScope Study
Colonic Polyps
Primary: Diagnostic Accuracy of In-vivo Polyp Assessment — 93.3; 94.7 % diagnostic accuracy
Phase 2 N=46 Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer
Attenuated Familial Adenomatous Polyposis · Familial Adenomatous Polyposis
Primary: Mean Percent Change in Duodenal Polyp Burden — -29.6 percent change in Duodenal Polyp Burden
N/A N=428 Impacts of Inspection During Instrument Insertion on Colonoscopy Quality
Colon Polyp · Colon Adenoma
Primary: Percentage of Participants With Detection of at Least One Adenoma Per Procedure — 63.7; 68.1 percentage of participants
N/A N=427 Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas
Sessile Serrated Adenoma
Primary: Sessile Serrated Adenomas — 42; 59 colonoscopies
Phase 3 N=58 Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA
Familial Adenomatous Polyposis Coli · FAP
Primary: Absolute Change in the Number of Polyps Measured in a Focal Area of the Rectum. — -0.5; 0.5 Change from baseline number of polyps. — p=0.005