N/A N=60 Dailies Total 1 Sphere Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Visual Analog Scale (VAS) Contact Lenses Comfort Scores — 44 Score on a scale — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=46 Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Contact Lens Discomfort · Dry Eye
Primary: Contact Lens Symptoms — 20.41; 18.92; 12.86; 17.92 Score on a Scale
N/A N=62 Contact Lens Comfort Relative to Meibomian Gland Status
Meibomian Gland Dysfunction
Primary: Comfort as Measured by the Contact Lens Users Experience Questionnaire (CLUE) — 58.67 units on a scale
N/A N=196 Non-dispense Comfort Comparison of Two Silicone Hydrogel Lenses
Myopia
Primary: Comfort After Insertion — 8.7; 7.7 Scale 1-10
N/A N=23 Connecting Contact Lenses and Digital Technology
Asthenopia · Contact Lenses · Ocular Accommodation
Primary: Subjective Symptom Improvement — 153.9; 100.7; 272.13 score on a scale — p=0.07
N/A N=30 Neurolens and Contact Lens Discomfort
Contact Lens Discomfort
Primary: Change in Contact Lens Discomfort — -4.94; -8.67 Scores on a scale
N/A N=80 Initial Performance of a Modified Daily Disposable Contact Lens
Refractive Error
Primary: Incidence (Number) of Ocular Discomfort Device-related Adverse Events (AEs) — 0; 0 Eyes
N/A N=88 Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers
Dry Eye Syndrome · Myopia
Primary: Mean Change From Baseline in Contact Lens-Related Dryness Symptoms at Week 1 and Week 2 — -0.09; -0.29 Units on a scale
N/A N=46 Treating Contact Lens Discomfort With Orthokeratology
Dry Eye · Contact Lens Complication
Primary: Contact Lens Comfort — 22.03; 9.83 Units on a Scale — p=<0.001
N/A N=126 Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
Myopia
Primary: Lens Awareness — 16; 12; 11; 9 Participants
N/A N=20 An Investigation of the Impact of Localized Topical Anesthesia of the Ocular Surface on End-of-day Contact Lens Discomfort
Visual Acuity
Primary: Subjective Comfort Scores — 79.25; 70.93; 61.00; 61.94 Units on a Scale
N/A N=441 Evaluation of Two Daily Disposable Contact Lenses.
Myopia
Primary: Percentage of Eyes With > Grade 2 Slit Lamp Findings — 0; 0 eyes
N/A N=63 Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
Myopia
Primary: Lens Awareness — 8; 9 Participants
N/A N=80 Evaluation of Marketed Soft Contact Lenses
Visual Acuity
Primary: Overall Quality of Vision Score — 56.9 Units on a scale
N/A N=120 Clinical Comfort Evaluation of Two Marketed Spherical Contact Lenses
Astigmatism
Primary: Comfort at Insertion — 8.7; 8.5 units on a scale
N/A N=100 Dispensing Evaluation of Subjective Comfort, Vision, and Handling of a New Lens Compared to a Marketed Lens
Refractive Ametropia
Primary: Subject Reported Overall Quality of Lens Vision Using the Contact Lens User Evaluation (CLUE) Questionnaire — 54.06; 53.06 units on a scale
N/A N=61 Evaluation of Comfilcon A and Senofilcon A Lenses
Myopia
Primary: Subjective Responses for Comfort Rated on a 0-100 Visual Scale. — 86; 87; 89; 91 units on a scale
N/A N=72 Ocular Comfort and the "Aging" Lens (ERBIUM)
Refractive Error
Primary: Phase 3: Ocular Comfort, Lens Age 1 Day, Hour 1 — 76; 88 Units on a scale
N/A N=438 A Study to Evaluate a Modified Contact Lens
Myopia
Primary: Percentage of Eyes With > Grade 2 Slit Lamp Findings — 0; 0 eyes
N/A N=37 Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Type
Dry Eye
Primary: Subjective Comfort at End of Day With Contact Lens Wear — 72.5 score on a scale
N/A N=92 Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens
Visual Acuity
Primary: Change From Baseline Comfort Score — 28.99; -0.29 Units on a scale
N/A N=35 Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use
Myopia
Primary: Subjective Rating of Comfort After 8 Hours or More of Digital Device Use — 96 score on a scale
N/A N=548 Clinical Study of Approved and Investigational Contact Lenses
Visual Acuity
Primary: Subjective Overall Comfort Composite Score — 65.17; 68.58; 66.45; 65.46 average clue score
N/A N=372 Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
Refractive Error · Myopia · Hyperopia
Primary: Likert Scale Questionnaire Item: "I Can Comfortably Wear my Lenses" — 4.2; 4.4 units on a scale
Phase 4 N=50 Corneal and Conjunctival Sensitivity and Staining Study
Myopia · Hyperopia
Primary: Corneal Sensitivity — 26.9; 25.5 percent CO2
N/A N=80 Initial Performance of a Daily Disposable Contact Lens Featuring Molded Marks
Refractive Error
Primary: Incidence of Ocular Discomfort Device-related Adverse Events (AE) — 0; 1 Events
N/A N=75 Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses
Visual Acuity
Primary: Overall Comfort (Phase I) — 45; 32; 20; 23 Number of responses
N/A N=121 Clinical Evaluation of Two Daily Disposable Silicone Hydrogel Contact Lenses
Myopia
Primary: End-of-day Comfort — 8.3; 6.6 Units on a scale
N/A N=24 Open Eye Corneal Swelling With Daily Disposable Contact Lenses and no Lens Wear
Corneal Swelling
Primary: Percentage Change From Baseline of Corneal Swelling 8 Hours Post Fit — 0.07; -0.02; 0.14; -0.06 percentage of change from baseline
N/A N=125 Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)
Healthy
Primary: Corneal Fluorescein Staining Type at Baseline — 1.7 Units on a scale