N/A N=175 Focused Field of View Calcium Scoring Prior to Coronary CT Angiography
Radiation Safety · Coronary Computed Tomography Angiography · Coronary Artery Disease
Primary: Qualitative Quality Comparison — 4; 4 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 Evaluation of Coronary Artery Calcification Using Gated Stationary Chest Tomosynthesis
Coronary Artery Disease
Primary: Comparison of CT Derived CACS and Tomosynthesis Scores Correlation
N/A N=70 Warfarin and Coronary Calcification Project
Coronary Calcification
Primary: Coronary Calcification (Presence and Degree as Measured by Agatston Score) Attributed to Duration of Warfarin Use in Months After Controlling for Standard Cardiovascular…
Phase 4 N=44 Vitamin D and Coronary Calcification Study
Chronic Kidney Disease · Vitamin D Deficiency · Coronary Calcification
Primary: Coronary Artery (CAC) Score Progression — 74.38; 106.32 Agatston units
N/A N=45 Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury
Spinal Cord Injuries · Heart Diseases
Primary: Percent Agreement Between Coronary Calcium Score (CCS) and National Cholesterol Education Program (NCEP) Guidelines — 18 percent agreement
N/A N=120 Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging
Coronary Disease
Primary: Ability to Detect Stress-induced Myocardial Perfusion Abnormalities by Analysis of MDCT Images Confirmed by Coronary Angiography and/or SPECT. — 78 % accurately detected…
Phase 2 N=20 Absolute Quantification of Coronary Flow Reserve by Stress Perfusion MRI
Myocardial Ischemia
Primary: Quantification of Myocardial Blood Volume — 3.63; 1.23 seconds^-1
N/A N=179 Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)
Coronary Arteriosclerosis · Arteriosclerosis, Coronary · Atherosclerosis, Coronary
Primary: Mean Coronary Wall Thickness — 2.0 mm
N/A N=105 Ultra Low Dose CT for CACS and AC of SPECT
Coronary Artery Disease
Primary: Agreement and Correlation of Coronary Artery Calcium Score Obtained From Ultra-low-dose and Standard CT — 212; 178 Agatston score
N/A N=306 Data Acquisition for Optimization of Coronary Artery Disease (CAD) Algorithm
Coronary Artery Disease
Primary: The Area Under the Receiver Operating Characteristic Curve of the CAD-score to Separate CAD From Non-CAD Patients. — 73.4 percentage of 100
N/A N=586 The Value of CT Fractional Flow Reserve
Angina, Stable Chest Pain
Primary: Comparison of CCTA Alone to FFR-CT After CCTA — 90.97; 92.73; 22.86; 69.71 percent — p=1.00
N/A N=1,748 Rapid Assessment of Potential Ischaemic Heart Disease With CTCA
Acute Coronary Syndrome
Primary: All-cause Death or Subsequent Non-fatal Type 1 or Type 4b MI at One Year Measured as Time to First Such Event. — 51; 53 Participants
Phase 4 N=110 Rivaroxaban Versus Warfarin in the Evaluation of Progression of Coronary Calcium
Atherosclerosis
Primary: Coronary Artery Calcium (Serial Calcium Scans) — 26.3; 40.5 mm cubed
N/A N=15 Coronary Flow Reserve Following Orbital Atherectomy
Coronary Artery Disease
Primary: Coronary Flow Reserve (CFR) — 2.23 Ratio
N/A N=37 Sodium Thiosulfate Treatment of Vascular Calcification in ESRD
Complication of Hemodialysis · Cardiovascular Diseases
Primary: Change in Annualized Coronary Calcium Volume Score After Treatment With Sodium Thiosulfate. — 6.6 mm3/year — p=0.001
N/A N=258 The REVEALPLAQUE Study: A pRospEctiVe, multicEnter Study to AnaLyze PLAQUE Using CCTA
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Primary: Comparison of Total Plaque Volume — 0.91 Pearson's correlation statistic
N/A N=1,392 Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)
Chest Pain · Acute Coronary Syndrome · Acute Myocardial Infarction
Primary: Rates of Major Cardiac Events (AMI or Cardiac Death) Within 30 Days — 0; 0; 0; 10 Participants
N/A N=885 Study in Subjects Suspected of Having CAD Undergoing VISIPAQUE-enhanced CCTA as Part of Their Routine Medical Care
Coronary Artery Disease (CAD)
Primary: The Sensitivity of Visipaque-enhanced Coronary Computed Tomography Angiography (CCTA) for Predicting Downstream Cardiovascular Events at Each Follow-up Period When…
N/A N=350 Multi-center Prospective Study to Evaluate Outcomes of the Moderate to Severely Calcified Coronary Lesions (MACE)
Coronary Artery Disease
Primary: MACE at 30 Days — 2.3; 3.1; 15 Percent probability of MACE
N/A N=27 Evaluation of Atorvastatin on Atherosclerosis Composition
Atherosclerosis
Primary: Change in Necrotic Core Volume — 0.07 mm^2
Phase 2 N=274 Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)
Cardiovascular Diseases · Cardiovascular Abnormalities · Calcifications, Vascular
Primary: Change in Log CAC Volume Score From Baseline to Week 52 for the Combined Dose Groups vs Placebo — 1.11; 1.20 ratio
Phase 3 N=55 Effect of Evolocumab on Coronary Atherosclerosis
Cardiovascular Disease · Hyperlipidemia
Primary: Change in Noncalcified Coronary Artery Plaque Volume (NCPV) — -45 mm^3
N/A N=900 Screening For Asymptomatic Obstructive Coronary Artery Disease Among High-Risk Diabetic Patients Using CT Angiography, Following Core 64
Coronary Artery Disease
Primary: Number of Participants With Combination of All Cause Death, Non-fatal Myocardial Infarction (MI), and Hospitalization for Unstable Angina — 34; 28 Participants
N/A N=150 Stress CT Perfusion in Patients With Chest Pain
Coronary Artery Disease
Primary: Number of Participants With Detected Stress-induced Perfusion Abnormalities by 3D Analysis of MDCT Images — 56 Participants
Phase 4 N=351 Assessment With CCTA and MRI in Asymptomatic Patients With Type 2 Diabetes for Detection of Unrecognized Myocardial Scar in Subclinical Coronary Atherosclerosis
Type 2 Diabetes Mellitus · Coronary Atherosclerosis
Primary: Prevalence of Occult Myocardial Scar on Delayed-enhanced MRI in Asymptomatic Patients With Type 2 Diabetes Mellitus — 23 Participants
N/A N=60 Rotational Atherectomy Combined With Cutting Balloon to Optimize Stent Expansion in Calcified Lesions
Coronary Artery Disease · Atherosclerosis
Primary: Minimum Stent Area After Percutaneous Coronary Intervention — 6.7; 6.9 mm^2
N/A N=21 PET MYOCARDIAL Blood Flow Comparison to Coronary CTA and CT-FFR
Coronary Artery Disease
Primary: Number of Flow-limiting Coronary Artery Stenosis on CT — 8 Coronary arteries
N/A N=75 Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.
Atherosclerosis, Coronary
Primary: Comparison of CT Based FFR With Invasive FFR, ROC Analysis — 0.8 probability of accurate diagnosis
N/A N=54 Effect of Citrate Dialysate on Vascular Calcification
Vascular Calcification
Primary: Length of Calcified Artery Segments — 47; 9 millimeters (mm) per year
Phase 3 N=426 Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Coronary Artery Disease
Primary: Presence of a Myocardial Perfusion Defect Indicating Significant CAD Per Participant on Gadobutrol-enhanced CMRI (Based on RPS) - Primary Analysis of Sensitivity Based…