Clinical Trial Search

Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…

Primary: Number of Lesions Showing Radiographic Progression as Measured by Lesion Size (Continuous) — 2; 11 Lesions — p=0.002

Primary: ICDAS Severity Value — 17; 22; 278; 273 teeth — p=0.1126

Primary: Number of Participants With Arrested Dental Caries, Assessed Using a Clinical Oral Examination — 48; 53 Participants

Primary: Parameters Evaluated After Treatment — 19; 19; 25; 3 Participants

Primary: Number of New Tooth Root Caries Lesions — 1.1; 0.43; 0.56 new carious root surfaces

Primary: Bacterial Count of Streptococus Mutans — 2.00; 2.04; 1.12; 1.05 CFU/ml log10

Primary: Root Caries Activity — 3.72; 40.52 Percentage of active lesions (2-years)

Primary: Proportion of Subjects With All Caries Arrested — 108; 101 Participants

Primary: Percentage of Participants Who Indicate Surgical Intervention — 74 percentage of the dentists

Primary: Clinical Outcome Based on Success After Intervention on MIH Affected Molar at 6 Months — 17; 18; 17 number of Successful MIH affected molars

Primary: Percent Surface Microhardness (SMH) Recovery of Enamel Specimens Exposed to NaF Toothpaste (1426ppmF) and AmF Toothpaste (1400ppmF) — 38.05; 41.06 Percentage SMHR…

Primary: Number of Participants With Treatment Failure — 2; 2 participants

Primary: International Caries Detection and Assessment System (ICDAS II) - Number of Molars With ICDAS Score of 3 or More - ICDAS Score 3, Cavity - — 0; 13 right or left second…

Primary: Caries Activity and Progression Assessment Using LASER Fluorescence Readings by Diagnodent® Device. — 18.6; 1.1 units on a scale

Primary: Failure Rate of the Three Treatment Arms Judged Clinically — 37; 31; 39; 2 Teeth — p=0.02

Primary: Interproximal Caries Zone of Radiolucency — 9; 7; 10; 12 Number of teeth

Primary: Mineral Loss ΔZ — 235; 774 vol% * μm]

Primary: Success Rate Based on Pulp Vitality Tests (Vital/Non Vital) — 96.2; 100; 100; 86 Percentage of success rate — p=>0.1

Primary: Percent Reduction in Apical Radio-lucency — 17.4; 27.1 % Change in Diameter (mm)

Primary: Number of Lesions With Progression as Measured by Pairwise (PW) Comparison (N=Lesions) — 4; 14 Lesions — p==0.003

Primary: Percentage Surface Microhardness Recovery (%SMHR) of Sound Enamel Specimens Exposed to NaF Toothpaste (1450ppmF) and NaF Toothpaste (1400ppmF) — 28.31; 26.32 Percentage…

Primary: Dental Caries Activity — .72; .05 Proportion of arrested caries lesions

Primary: Number of Lesions That Received Invasive Treatment and the Number of Lesions Receiving Invasive Treatment That Extended Into Dentin — 603; 246; 213; 248 lesions

Primary: Overall Arrest Rates — 81.3; 61.5; 78.1; 95.8 percentage of lesions arrested

Primary: Antimicrobial Activity of C16G2 — -0.2; -0.04; 0.005; 0.15 CFU/mL

Primary: Percentage Surface Micro-hardness Recovery (SMHR) of Enamel Specimens — 39.46; 38.31; 36.17; 17.26 % SMHR — p=0.7756

Primary: Change in Bacterial Composition Before and One Month After SDF Application to Root or Cervical Caries Lesions — 1890087; 1959306 bacterial count

Primary: Mean Percentage Surface Microhardness Recovery (%SMHR) of Enamel Specimens Exposed to NaF/Carbopol Toothpaste (1400 ppmF), NaF Toothpaste (1350ppmF) Compared to…

Primary: Caries Arrest of Teeth in the SDF Group Measured by Change in Size — 10 Participants