Phase 3 N=25 Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.
Gingival Diseases
Primary: Plaque Index — 2.45; 2.22; 2.54; 2.56 Units on a scale — p=0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=23 Clinical Study to Evaluate Dental Plaque
Gingival Diseases
Primary: Dental Plaque Index — 2.48; 2.42 Units on a scale — p=0.05
N/A N=135 Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material
Dental Caries · Restorative Material
Primary: Percent of Teeth With Anatomic Form Graded as A or B. — 42; 37; 40; 2 teeth — p=0.2552
Phase 2 N=28 Evaluating Commercial Anti-Plaque Products and Oral Rinse
Dental Plaque
Primary: Plaque Index — 2.63; 2.65; 1.23 Units on a scale — p=0.05
Phase 4 N=129 The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US
Dental Plaque · Gingivitis
Primary: Dental Plaque Scores — 3.91; 3.86; 3.84 units on a scale — p=0.652
N/A N=42 Efficacy of Plaque Removal of a Novel Brushing Device
Dental Plaque
Primary: Change From Baseline in Dental Plaque Removal Efficacy Using Turesky Modification of the Quigley-Hein Plaque Index — 0.29; 0.6 units on a scale
Phase 3 N=323 Preventing and Arresting Dental Root Surface Caries in Community-dwelling Older Adults
Dental Caries
Primary: Number of New Tooth Root Caries Lesions — 1.1; 0.43; 0.56 new carious root surfaces
Phase 3 N=120 The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis
Dental Plaque · Gingivitis
Primary: Dental Plaque Scores — 3.33; 3.19; 3.31 units on a scale — p=0.434
N/A N=102 Cold Plasma for Dental Restoration and Caries Prevention
Dental Restoration · Caries
Primary: Number of Decayed, Missing and Filling Teeth (DMFT) — 6.29; 5.14 teeth
Phase 3 N=73 Clinical Research Study Efficacy of a Prototype Oral Rinse
Dental Plaque
Primary: Gingival Index — 1.90; 1.84 Units on a scale — p=0.005
N/A N=230 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -0.96; -0.77 Score on a scale — p=0.1575
N/A N=12 Dental Office Prevention Strategies for Children
Dental Plaque
Primary: Dental Plaque Levels Measures on Scale of 0-2 — 0.391 units on a scale
N/A N=50 Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Dental Caries · Denture, Partial, Removable
Primary: Mineral Loss ΔZ — 235; 774 vol% * μm]
Phase 3 N=105 Clinical Study to Examine Brushing on Dental Implants
Gingival Diseases
Primary: Mombelli Plaque Index (mPI) for Natural Teeth — 1.96; 1.82 units on a scale — p=0.05
Phase 4 N=49 A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
Gingivitis
Primary: Mean Bleeding Index (BI) at Week 12 — 0.45; 0.76 Score on a scale — p=<0.0001
N/A N=42 Dental Implant Study Comparing Two Types of Metals Used for Dental Implants
Tooth Replacement
Primary: Fold Change in Gene Expression Comparing Trabecular Metal to Standard Titanium. — 7.6758; 9.2208; 4.6085; 5.2331 Average Delta ∆ (Ct)
N/A N=282 Assessment of Caries Diagnosis and Caries Treatment in Dental PBRN Japan
Dental Caries
Primary: Percentage of Participants Who Indicate Surgical Intervention — 74 percentage of the dentists
N/A N=5,117 Periodontal Disease Prevention Study
Periodontitis
Primary: Percentage of Participants With Tooth Loss Over 16 Year Period — 16.4; 13.8; 22.1; 16.9 percentage of participants
N/A N=1,305 Family Access to Dentist Study
Dental Caries
Primary: Number of Participants With Receipt of Dental Care-restoration or Extraction of at Least One Tooth at Final Exam — 68; 76; 8; 14 Participants — p=<0.05
N/A N=76 Clinical Trial NuSmile Crowns
Primary Dental Caries, Multisurface Origin (Diagnosis)
Primary: Fitting — 37; 42; 48; 3 Teeth
Phase 2 N=20 Experimental Dentifrice Remineralization/Fluoride Uptake in an in Situ Model
Dental Erosion
Primary: Percentage Surface Micro-hardness Recovery (SMHR) of Enamel Specimens — 39.46; 38.31; 36.17; 17.26 % SMHR — p=0.7756
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
N/A N=68 Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
Orthodontic Pathological Resorption of External Root · Complication of Personal Oral Hygiene
Primary: Plaque Index — 0.5; 0.7; 0.7; 0.8 Plaque Index (PI)
Phase 3 N=25 Evaluate Clinical Research From Commerical Oral Care Products
Gingival Diseases
Primary: Dental Plaque Index — 2.79; 2.82; 1.99 Units on a scale — p=<0.05
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
Phase 2 N=162 The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
Dental Plaque and Gingivitis
Primary: Gingivitis Scores — 1.48; 1.57; 1.49 units on a scale — p=0.091
Phase 3 N=29 Clinical Study to Compare Dental Plaque Control
Dental Plaque
Primary: Dental Plaque Index — 3.12; 2.90; 2.92; 2.94 Units on a scale — p=<0.05
Phase 3 N=60 Effectiveness of a Triclosan Containing Toothpaste in Maintaining Periodontal Health in a Type 2 Diabetic Population
Periodontitis
Primary: HbA1c Levels in Blood — 11.42; 10.81 percentage of HbA1c levels in blood — p=0.05
N/A N=10 Evaluation of Toothbrush Bristles in Plaque Reduction
Plaque, Dental · Gingivitis
Primary: Change of Navy Plaque Index (Navy Pl) After One-time Brushing — 367.5; 346.5; 355; 145.4 score on a scale
N/A N=45 Efficacy of Three Toothpastes Using an in Situ Caries Model
Dental Caries
Primary: Percentage Surface Microhardness Recovery (SMHR) of Phyte (0% 0.425% and 0.85%) at 2 Weeks — 25.53; 26.81; 7.41; 28.88 % SMHR — p=0.7603