N/A N=5,325 Digital Detection of Dementia (D Cubed) Studies: D2
Alzheimer Disease and Related Dementias (ADRD)
Primary: 12-Month Cumulative Incidence of ADRD Diagnoses — 213; 134; 355 Number of new ADRD cases — p=0.006
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=306 DreamKit Diagnostic Validation
Sleep Apnea, Obstructive · Sleep Apnea, Central
Primary: Intraclass Correlation Coefficient (ICC) of the Apnea Hypopnea Index — 0.964 intraclass correlation coefficient (ICC)
N/A N=135 Diagnostics in the Leg Ulcer Pathway
Venous Leg Ulcer
Primary: Primary Care Practitioners and the Management of Venous Leg Ulcers. — 50; 34; 45 Participants
N/A N=4,350 Reducing Diagnostic Errors in Primary Care Pediatrics (Project RedDE)
Diagnostic Errors
Primary: Number of Adolescents Diagnosed With Depression Seen in Well Child Visits — 233; 443 Participants — p=<0.0001
N/A N=109 Trial of Simulation-based Mastery Learning to Communicate Diagnostic Uncertainty
Uncertainty · Communication Research · Emergency Medicine
Primary: % of Residents Who Pass the UCC at the T2 Assessment — 29; 2 Participants
N/A N=231 Diagnostic Precision of the AI Tool Dermalyzer to Identify Malignant Melanomas in Subjects Seeking Primary Care for Melanoma-suspected Cutaneous Lesions
Malignant Melanoma
Primary: Diagnostic Accuracy to Detect Melanoma — 20; 92; 1; 140 number of skin lesions
Phase 3 N=402 Reducing Diagnostic Error to Improve Patient Safety in COPD and Asthma (REDEFINE Study)
COPD Asthma
Primary: Total Number of Healthcare Visits — 111; 76; 119; 93 Participants
N/A N=46 Measuring and Improving the Safety of Test Result Follow-Up
Lung Cancer · Breast Cancer · Colon Cancer
Primary: Trigger Outcome — 67.0; 65.9; 78.6; 78.1 percentage of abnormal tests w/ followup
N/A N=92 Developing a Practice-Based Learning and Improvement Quality Improvement (QI) Systems Impact Assessment Questionnaire
Quality Improvement
Primary: Beliefs About Ability to Implement a CQI Project — .80; .28 units on a scale — p=0.02
N/A N=604 Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes
Diabetic Foot · Peripheral Arterial Disease · Diabetic Foot Ulcer
Primary: Diagnostic Accuracy — 36; 42; 55; 41 percentage
N/A N=548 Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)
Alzheimer Disease · Mild Cognitive Impairment · Memory Disorders
Primary: Change in Diagnostic Area Under the Receiver Operating Characteristic Curve (ROC-AUC) — 0.94; 0.91 probability
N/A N=237 Clinical Evaluation of the InflammaDry Device for Detecting Dry Eye
Dysfunctional Tear Syndrome
Primary: Negative and Positive Agreement of the InflammaDry at Diagnosis of Dry Eyes — 81; 98; 86; 97 percentage of cases
N/A N=40 Evaluation of a Pocket-Sized Ultrasound Device As an Aid to the Physical Examination
Splenomegaly · Pleural Effusion
Primary: Comparison of Diagnostic Ability of the Intervention Group's Ultrasound Exam to the Control Group's Physical Exam — 6.4; 7.6; 79.6; 79.3 units on a scale — p=0.11
N/A N=2,000 Primary Diagnosis Study for Validation of Hamamatsu NanoZoomer S360MD Digital Slide Scanner System
Pathology
Primary: Major Discordance Rate — 3.5; 3.1 Percentage of Major Discordances
N/A N=1,201 5-Cog Battery for Detecting Cognitive Impairment and Dementia
Dementia · Cognitive Impairment · Mild Cognitive Impairment
Primary: New Occurrence in Dementia Care-A Composite Endpoint Including New Cognitive Diagnoses, Laboratory Investigations Related to Cognitive Impairment, New Dementia…
N/A N=16 Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
Nutritional and Metabolic Diseases
Primary: Number of Test Results Outside the Normal Range — 6; 3; 0; 0 participants
N/A N=2,000 Pivotal Study for Validation of Philips Dx (PDx)
Pathologic Processes
Primary: Major Discordance Rate — 4.4; 4.7 percentage of major discordance
N/A N=51 Evaluation of DIDGET TM World Reports
Diabetes
Primary: Number of Participants Who Rated Successful (<=3) by Healthcare Professionals When Participants Performed Specific Software Tasks — 50; 50; 50; 50 participants
N/A N=23 Clinical Evaluation of the Carestream PRO 3543 and PRO 3543C Digital Detectors
Healthy
Primary: Radlex Scale for Diagnostic Capability Ratings — 3.0610; 3.0633 units on a scale — p=0.415
N/A N=16 Evaluation of TaiHao Breast Ultrasound Diagnosis Software
Breast Cancer · Breast Diseases
Primary: Comparing the Area Under the LROC Curve — 0.7786; 0.8160 probability — p=<0.05
N/A N=3,085 Decision Aids for the Management of Suspicious Occlusal Caries Lesions
Dental Caries
Primary: Number of Lesions That Received Invasive Treatment and the Number of Lesions Receiving Invasive Treatment That Extended Into Dentin — 603; 246; 213; 248 lesions
N/A N=35 Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection
Dental Caries
Primary: Caries Extension According to Diagnocam Codes 0-4 (Intra- and Interrater-Reliability, Sensitivity and Specificity) — 0.68; 0.87; 0.62; 0.76 weighted Kappa
N/A N=328 Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
Lichen Sclerosus · Lichen Planus · Lichen Simplex Chronicus
Primary: Diagnostic Accuracy of "Three Rings Vulvoscopy" by the "Vulvoscopy Index" for Detection of Vulvar Dermatosis — 72; 0; 10; 246 Participants — p=0.6108
N/A N=1,121 PROJECT 2 EXAMPLE: Feedback X Prevalence Using Dermatology Stimuli
Decision Making
Primary: Change in D' Between Pairs of Blocks. — -0.138; .0754; 0.023; -.129 z-score
N/A N=438 Evaluation of VA's Traumatic Brain Injury (TBI) Clinical Reminder and Comprehensive TBI Evaluation (CTBIE)
Traumatic Brain Injury
Primary: Diagnostic Accuracy of the TBI Clinical Reminder Screen (TCRS) — 71; 79; 74; 85 Percentage of participants
N/A N=150 Evaluation of CL Detect™ Rapid Test to Detect Cutaneous Leishmaniasis
Skin Diseases
Primary: True Positive — 0 samples
N/A N=711 Cognoa ASD Diagnosis Aid Validation Study
Autism Spectrum Disorder
Primary: Positive and Negative Predictive Value of ASD Dx in Relation to Clinician Diagnostic Evaluation — 80.8; 98.3 percent
N/A N=541 Assessment of Acute Disease to Reduce Imaging Costs
Acute Coronary Syndrome · Pulmonary Embolism
Primary: Efficiency--Mean Cost of Care — 3933; 2761 US Dollars
N/A N=16 Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction
Diastolic Dysfunction
Primary: Change in Left Ventricle Mean Diastolic Pressure — 3.3 mmHg
N/A N=62 Clinical Evaluation of an Integrated PET/MRI System
Subjects With Clinical Indication for PET/CT
Primary: Number Usable PET/MRI Image Sets — 70 Usable image sets