Phase 2 N=26 Pupil Dilation for Treatment of IFIS
Intraoperative Floppy Iris Syndrome
Primary: Pupil Dilation Sized of the Treated Eye Compared to the Non-treated Eye — 6.76; 7.17 millimeters
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=42 DilaCheck Cervical Dilation Measurement Trial
Cervical Dilation · Labor Pain · Labor Fast
Primary: Interexaminer Agreement — 9; 4 Participants
N/A N=419 Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb
Pre-induction Dilation of Cervix
Primary: Rate of Vaginal Delivery — 169; 159 Participants
N/A N=72 Dilapan Versus Laminaria
Cervical Preparation
Primary: Procedure Time — 5.9; 8.1 minutes
N/A N=300 Cervical Preparation Before Dilation and Evacuation
Abortion, Induced
Primary: Operative Time — 6.27; 6.28; 5.53 minutes
Phase 2 N=42 Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Down Syndrome · Refractive Errors
Primary: Distance Visual Acuity — 0.41; 0.41; 0.40; 0.43 logMAR — p=0.92
N/A N=180 Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Second Trimester Abortion
Primary: D&E Procedure Time — 7.35; 7.55 minutes
Phase 3 N=60 Evaluation of Coronary Luminal Diameter Enlargement With Emerge™ 1.20 mm PTCA Dilatation Catheter
Coronary Artery Disease
Primary: Device Procedural Success — 98.3 percentage of participants
N/A N=26 Outcomes of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management
Esophageal Dilation · Refractory Benign Esophageal Stricture
Primary: Number of Endoscopic Interventions — 12; 11; 12; 7 endoscopies
Phase 4 N=24 Oral Sedation During Cervical Dilator Placement
Oral Sedation and Cervical Dilator Pain
Primary: Cervical Dilator Placement Pain as Assessed by VAS on a Tablet Device — 55; 44 units on a scale
N/A N=125 Misoprostol Versus Dilapan-S for Cervical Preparation
Cervical Ripening
Primary: Cervical Dilation in Women Following Exposure to Either Ripening Agent — 32.1; 33.9 mm
N/A N=32 Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
Abortion, Second Trimester
Primary: Procedure Time — 22.4; 22.6 minutes
Phase 4 N=307 Comparison of Misoprostol Ripening Efficacy With Dilapan
Labor Onset and Length Abnormalities · Induced; Birth
Primary: Number of Women Achieving Vaginal Delivery Within 36 Hours After Initiation of Cervical Ripening in ITT Population — 93; 90 Participants
Phase 4 N=13 The Effect of Brimonidine
Intraocular Pressure
Primary: Intraocular Pressure — 15.4; 16.3; 16.5; 16.7 millimeters of mercury (mmHg)
Phase 1 N=19 Radial Artery Dilation Study: The Effect of Topical Administration of Nitroglycerin and Lidocaine Versus Lidocaine Alone of the Radial Artery Diameter
Healthy
Primary: Percent Change in Diameter of Radial Artery as a Dose Test for Nitroglycerin — -0.8; -0.2; 6.4; 2.5 percent diameter change
Phase 4 N=61 Evaluation of Pupil Dilation Speed With the MAP Dispenser
Mydriasis
Primary: Mean Change in Pupil Diameter From Baseline — 4.55; 4.88 millimeters
N/A N=50 Study of the Efficiency of Esophageal Dilation on Patient With Eosinophilic Esophagitis
Suspected Eosinophilic Esophagitis
Primary: Percent Change From Baseline in Dysphagia Score in Patients With Eosinophilic Esophagitis (EE) — 69; 79 Percent Change
Phase 3 N=50 Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks
Cervical Preparation
Primary: Length of Procedure — 14; 13.5 minutes
N/A N=60 XprESS Eustachian Tube Dilation Study
Eustachian Tube Dysfunction
Primary: Change From Baseline in Mean Overall ETDQ-7 Scores — -2.9; -0.6 units on a scale — p=<0.0001
Phase 4 N=11 Wearing-Off Period of Pharmacological Dilation and Anisocoria
Anisocoria
Primary: Number of Participants With Constricting Response to Pilocarpine 1% in the Pharmacologically Dilated Eye — 3 Participants
N/A N=50 Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
Abortion, Induced
Primary: Procedure Time — 10.9; 11.8 minutes
Phase 1 N=36 Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium
Sinusitis
Primary: Patency of Treated Area — 95 percentage of ostia treated
N/A N=50 Sinus Balloon Dilation in Pediatric Patients
Sinusitis
Primary: Technical Success: Sinuses Successfully Treated With Balloon Dilation — 157 sinus dilation attempts
N/A N=21 XprESS Maxillary Balloon Dilation Study
Chronic Sinusitis · Chronic Rhinosinusitis (Diagnosis)
Primary: SNOT-20 Score — 2.3; 0.8 score on a scale — p=<0.0001
N/A N=80 Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services
Legally Induced Abortion Without Mention of Complication
Primary: Procedure Time — 13; 12; 18.5 minutes
Phase 3 N=64 Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation
Mydriasis
Primary: Change in Pupil Diameter From Baseline — 2.672; 2.583; 2.657; 2.569 millimeters
Phase 4 N=178 Intrafetal Digoxin as an Adjuvant for Dilation and Evacuation at 20 to 24 Weeks' Gestation
Abortion
Primary: Procedure Duration — 6.8; 7.2 minutes
N/A N=100 Efficacy of the Nanodropper Device on Pupillary Dilation
Dilation
Primary: Spherical Equivalent — -2.62; -2.28; -0.86; -0.55 Diopters — p=0.22
N/A N=82 Trans-Nasal Maxillary Multi-Sinus Balloon Dilation Study
Sinusitis
Primary: Change in SNOT-20 Score — 2.3; 0.7 score on a scale — p=<0.0001
Phase 4 N=30 Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil Dilation
Mydriasis
Primary: Mean Change in Pupil Diameter — 3.73; 6.46 millimeters