N/A N=132 Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients
Vitamin B12 Deficiency
Primary: Change in Amount of Epogen Required — -16,572 unit/ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=21 Evaluation of Holotranscobalamin as an Indicator of Vitamin B12 Absorption
Disorder of Vitamin B12
Primary: Change in Holo-transcobalamin — 124 pmol/L
N/A N=366 Randomized Trial of Vitamin B12 in Pregnant Indian Women
Pregnancy
Primary: Changes in Maternal Serum B12 Concentration From 1st to 3rd Trimester — 3.0; -37.6 pmol/L
Phase 2 N=20 A Trial of Vitamin B12 in Septic Shock
Septic Shock
Primary: Feasibility of Clinical and Protocol Completion — 10; 10 Participants
N/A N=30 Natural Versus Synthetic Vitamin B Complexes in Human
Healthy · Thiamine and Niacin Deficiency States · Pyridoxine Deficiency
Primary: Serum Thiamine — 50.21; 48.33; 51.21; 50.60 "µg/L"
N/A N=41 Vitamin B12 for Aromatase Inhibitors Musculoskeletal Symptoms
Relief of Joint Pain
Primary: Percentage Change in Average Joint Pain in Women With Aromatase Inhibitor-associated Musculoskeletal Symptoms (AIMSS) Compared to Baseline as Measured by the Brief Pain…
N/A N=125 Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
Vitamin B12 Deficiency
Primary: Prevalence of Vitamin B12 Deficiency — 3; 6; 4 participants
Phase 3 N=57 Trial of Methyl B12 on Behavioral and Metabolic Measures in Children With Autism
Autistic Disorder
Primary: Clinical Global Impression-Improvement (CGI-I) — 3.1; 2.4 CGI- Improvement
N/A N=63 Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia
Cardiovascular Abnormalities
Primary: Change in Plasma Total Homocysteine Concentration (tHcy) — 1.9; 2.7; 0.5 mcmol/L — p=<0.05
Phase 4 N=140 Effectiveness of Vitamin Supplementation in Treating People With Residual Symptoms of Schizophrenia
Schizophrenia
Primary: Positive and Negative Syndrome Scale (PANSS) — -.21; -.22 units on a scale
N/A N=206 Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans
Thiamine Deficiency · Thiamine Deficiency; Sequelae
Primary: Percentage of Participants With Thiamine Deficiency (Low Plasma Thiamine) Out of Total Number of Enrolled Veterans With Plasma Thiamine Results — 49 Participants
Phase 3 N=12 Betaine and Peroxisome Biogenesis Disorders
Peroxisome Biogenesis Disorders
Primary: Peroxisome Biochemical Functions as Measured by Plasma Very Long Chain Fatty Acid — 0.180; 0.188 ratio
Phase 3 N=319 A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients
Cancer
Primary: Neurotoxicity Assessment at Baseline — 8.5; 7.3; 5.23; 4.58 units on a scale
N/A N=28 Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes
Diabetes Type 2
Primary: Diff AUC SS0.5 Hyperglycemic — 0.74; 0.96 Pa*hr
Phase 4 N=120 High Dose Vitamin B1 to Reduce Abusive Alcohol Use
Alcoholism
Primary: Change in Average Daily Alcohol Consumption — -3.4; -3.0 alcoholic drinks per day
Phase 3 N=13 Vitamin B6 Effects for Women Taking Birth Control Pills
Vitamin B6 Deficiency
Primary: Total Remethylation of Homocysteine — 6.07; 5.63 micromol/(kg x hr) — p=0.20
N/A N=19 Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery
Vitamin D Deficiency · Gastrointestinal Diseases
Primary: # of Pts w/ Enhanced Vitamin D Status — 3; 3 Participants
Phase 4 N=7 The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine
Vitamin B1 Deficiency · Thiamine Deficiency
Primary: Maximum Concentration (Cmax) of Thiamine in Plasma Between the Combination Arm(s) and Single Agent Arm — 15; 32 nM
Phase 4 N=214 Study of Metanx® in Subjects With Type 2 Diabetic Peripheral Neuropathy (DPN)
Type 2 Diabetic Peripheral Neuropathy (DPN)
Primary: Change From Baseline in Vibration Perception Threshold (VPT) at 24 Weeks — 32.16; 33.88; -1.96; -3.27 volts
N/A N=37 Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
Obesity · Vitamin D Deficiency
Primary: Vitamin D Concentrations, Pre Operative and Post Bariatric Surgery Following 12 Weeks of Vitamin D Supplementation — 19.1; 27.2 ng/mL — p=< 0.001
N/A N=180 Magnesium Treatment on Vitamin D Metabolism in Participants Completed Personalized Prevention of Colorectal Cancer Trial
Colorectal Cancer
Primary: Comparisons of the Changes of Blood 25-Hydroxyvitamin D3 (25(OH)D3) Between Magnesium Treatment and Placebo Arm, Stratified by the Baseline 25-hydroxyvitamin D (25(OH)D)…
N/A N=84 Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities
Respiratory Distress Syndrome
Primary: Respiratory Distress Syndrome — 52; 3 participants
Phase 2 N=23 The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
Psoriasis
Primary: Subjects Achieving 50% or Greater Psoriasis Area and Severity Index (PASI) Reduction — 2; 2 Participants
Phase 4 N=38 Folate Supplementation in Schizophrenia
Schizophrenia
Primary: Correlation Between Baseline Blood Folate and Smoking Status — 14.6; 14.6; 14.2; 614 nanograms per milliliter
Phase 2 N=4 A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations
Myelodysplastic Syndromes
Primary: Number of Patients Who Experienced a Dose Limiting Toxicity (DLT) — 0; 0; 0 Participants
N/A N=68 Improving Vitamin D Status in Home-bound Elders
Vitamin D Deficiency · Accidental Falls
Primary: Change in 25-hydroxyvitamin D Levels Over 5 Months — 21.7; 0 ng/mL
N/A N=20 Vitamin D Supplementation in Kidney Disease
Renal Dialysis · Vitamin D Deficiency
Primary: Change in Hip Flexor Strength — 20.34; 6.83 percent change
Phase 3 N=402 Sub-clinical Inflammation and Iron Supplementation
Anemia
Primary: Haemoglobin Level — 88.3; 89.2; 88.4; 89.6 g/L — p=<0.05
N/A N=81 Optimizing Vitamin D in the Elderly
Deficiency of Vitamin D3
Primary: Total 25-OH Vitamin D3 Level — 33; 34; 43; 61 ng/mL — p=<.0001
N/A N=33 Vitamin D Supplementation for Bipolar Depression
Bipolar Disorder · Bipolar Depression
Primary: Change in Montgomery-Åsberg Depression Rating Scale — 9.4; 6.4 units on a scale — p=0.89