N/A N=22 Enhancing Emotion Regulation During Driving in OEF/OIF Veterans
Driving Distress Secondary to Trauma During Deployment
Primary: Reduced Heart Rate During Driving (Aggregated Over Sessions) — 3.21; 9.0 beats per minute
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=345 Project SERVE: Post Deployment Functioning
Post-traumatic Stress Disorder · Depressive Disorder · Alcoholism
Primary: World Health Organization Disability Assessment Schedule II (WHODAS II) — 1.87; 2.03; 2.07; 1.88 units on a scale
N/A N=50 Enhanced Problem-Solving Training
Brain Concussion
Primary: Brief Symptom Inventory-18 (BSI-18) Global Severity Index T-Score — 64.21; 65.26; 66.8; 61.35 units on a scale — p=.04
N/A N=176 One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change
Traumatic Brain Injury · Chronic Pain · Post Traumatic Stress Disorder
Primary: The Depression Anxiety and Stress Scale (DASS-21) -TOTAL Score — 28.97; 30.77 units on a scale
N/A N=342 Psychophysiologic Predictors of Post-deployment Mental Health Outcomes
Post-traumatic Stress Disorder
Primary: The PTSD Checklist - Military Version — 22.2; 23.7; 23.8; 25.9 units on a scale
N/A N=50 Effects of Deployment Exposures on Cardiopulmonary and Autonomic Function
Abnormality, Respiratory System · Autonomic Nervous System
Primary: FEV1 — 0.94; 1.08; 0.95; 1.09 percentage of predicted normal values
N/A N=55 Cognitive-Behavioral Therapy for Veterans With TBI
Insomnia · Traumatic Brain Injury
Primary: Change in Insomnia Severity — 8.833; 7.810; 9.625; 8.364 score on a scale
N/A N=128 Cognitive Rehabilitation of Operations Iraqi Freedom and Enduring Freedom (OIF/OEF) Veterans With Cognitive Disorder
Cognition Disorders
Primary: Multiple Sclerosis Neuropsychological Screening Questionnaire-Patient Version — 33.58; 36.35 units on a scale
N/A N=39 One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology
Mild Traumatic Brain Injury · Distress-based Psychopathology · Chronic Pain
Primary: World Health Organization-Quality of Life (WHO-QOL) — 6.11; 5.20 units on a scale
N/A N=83 Family Involvement in Treatment for PTSD
Posttraumatic Stress Disorder
Primary: Qualitative Interviews - Perspectives on Family Involvement in PTSD Treatment — 33; 20; 27; 16 participants — p=<0.05
N/A N=248 Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI
Mild Traumatic Brain Injury · Posttraumatic Stress Disorders · Depression
Primary: Change in the Community Reintegration of Injured Service Members Computer Adaptive Test (CRIS-CAT) — 36.4; 35.0; 38.2; 35.1 score on a scale
N/A N=26 Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD
Substance Use Disorder · Post-traumatic Stress Disorder · Moral Injury
Primary: Self-Compassion Scale (SCS); Change From Baseline in Self-Compassion at Post-treatment — 0.45 score on a scale
N/A N=134 PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Post Traumatic Stress Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Checklist (PCL) — 66.94; 66.33; 51.20; 60.60 score on a scale
N/A N=145 Trauma Informed Guilt Reduction Therapy
Guilt · Shame · Post-traumatic Stress Disorders
Primary: Trauma Related Guilt Inventory - Guilt Severity — 2.5; 2.5; 1.6; 2.2 score on a scale
N/A N=81 Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
Posttraumatic Stress Disorders · Combat Disorders · Alcohol Dependence
Primary: Change in Post-traumatic Stress Disorder Symptomatology — -51.2; -35.9; -22.3; -10.9 score on a scale
N/A N=6 Team Based Initiative Support
Traumatic Brain Injury
Primary: Number of Participants Who Reported 5 Themes — 6; 6; 6; 6 participants
N/A N=92 Treatment of Trauma-Related Anger in OEF/OIF/OND Veterans
Anger Problems
Primary: Least Squares Mean Anger Expression Index Score on the State Trait Anger Inventory 2 (STAXI-2) Using a Repeated Measures ANCOVA Adjusted for Baseline and Time Effects…
N/A N=174 Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure
Post-traumatic Stress Disorder · Moral Injury · Traumatic Loss
Primary: Change in Functional Impairment Assessed Through the Sheehan Disability Scale (SDS) — 20.52; 20.43; 17.39; 18.04 Score on a scale — p=0.03
N/A N=120 Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Post-traumatic Stress Disorder · Alcohol Abuse · Alcohol Dependence
Primary: Number of Patients With High Levels of Adolescent PTSD Symptoms — 9; 12; 11; 12 Participants — p=0.71
N/A N=359 Pain, Psychiatric Disorders, and Disability Among Veterans With and Without Polytrauma
Chronic Pain
Primary: Numeric Rating Scales of Pain Over Past Week (11 Point Likert Scale) — 4.66; 3.80; 4.92; 3.30 units on a scale
N/A N=23 Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD
Chronic Musculoskeletal Pain · Posttraumatic Stress Disorder (PTSD) · Mild or Moderate Traumatic Brain Injury
Primary: Change From Baseline: PTSD Checklist-5 (PCL-5) — 15.64 units on a scale — p=.040
N/A N=100 A Novel Posttraumatic Stress Disorder Treatment for Veterans With Moral Injury
Moral Injury
Primary: World Health Organization Quality of Life-BREF — 53.35; 52.39 score on a scale — p=0.729
N/A N=25 DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD
Stress Disorders, Post-Traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 63.08; 61.71; 42.83; 51.65 units on a scale
N/A N=46 Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
Post Traumatic Stress Disorder · Mild Traumatic Brain Injury, Concussion
Primary: Change in Performance on Neurocognitive Measure of Attention and Executive Function Post GOALS Intervention vs EDU Control Training — -0.03; -0.39 z score — p=<0.01
N/A N=21 Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Chronic Pain · PTSD
Primary: Feasibility of Recruitment as Assessed by Number of Participants Enrolled in the Study — 21 Participants
N/A N=120 Improving Function Through Primary Care Treatment of Posttraumatic Stress Disorder (PTSD)
Posttraumatic Stress Disorder
Primary: World Health Organization Disability Assessment Scale 2.0 Change — -7.5; -4.3 units on a scale — p=0.33
N/A N=81 Cognitive Training for PTSD
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale - Reexperiencing — 2.6; 2.96 score on a scale
N/A N=40 A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
Posttraumatic Stress Disorder · Depression · Alcohol-Related Disorders
Primary: Change From Baseline PTSD Checklist Civilian (PCL-C) at 1 Month — 1.30; 5.04 score on a scale
Phase 2 N=79 Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
Post-concussive Symptoms · Traumatic Brain Injury
Primary: Post-Intervation Post-concussion Symptom Scores Using RPQ - Intent to Treat — 3.5; 5.1; 4.2; 3.5 units on a scale
N/A N=20 Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale for DSM-5 to Assess Changes in PTSD Symptoms. — 35.3; 11.33 score on scale