N/A N=45 Ankle Robot to Reduce Foot Drop in Stroke
Stroke · Foot Drop
Primary: Gait Velocity During Self-selected Overground Walking — 0.48; 0.48; 0.54; 0.56 CM/SEC
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Augmenting Gait in a Population Exhibiting Foot Drop With Adaptive Functional Electrical Stimulation
Foot Drop
Primary: Mean Dorsiflexion at Heel Strike — 5.2 degrees
N/A N=110 Functional Electrical Stimulation for Footdrop in Hemiparesis
Stroke · Hemiplegia
Primary: Fugl-Meyer Motor Assessment (FMA) — 20.1; 20.3; 21.5; 21.18 units on a scale
N/A N=197 Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
Sensorimotor Gait Disorder · Neurologic Ambulation Disorder · Gait, Drop Foot
Primary: Ten Meter Walk Test (10mWT) — 0.15; 0.14 meters per second (m/s) — p=0.75
Phase 4 N=11 Assessment of Gait After Dysport Treatment
Equinovarus; Acquired
Primary: Self-Selected Velocity (SSV) — 0.41; .48; 0.48; 0.52 m/s
N/A N=28 Ankle-foot Orthoses for Peripheral Artery Disease
Peripheral Artery Disease
Primary: Change in WIQ Distance Subscore — 22.7; -7.2 Scale units
N/A N=60 Metatarsal Phalangeal Joint Deformity Progression - R01
Diabetes Mellitus (DM)
Primary: Change in Metatarsal Phalangeal Joint Angle (Degrees) in People With Diabetes From Baseline and at a 3-year Period — 0.8; -0.1 degrees
N/A N=22 Plantarflexion Reduces Urgency and Peak Detrusor Pressure in Patients With Detrusor Overactivity
Overactive Detrusor
Primary: Mean Peak Detrusor Pressures — 58; 31 cm H2O
N/A N=23 Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.
Stroke · CVA · Hemiplegia
Primary: Gait Endurance — 203.44; 195.15 Meter — p=.293
N/A N=21 Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
Cerebral Palsy (CP)
Primary: Change in Baseline Gait Profile Score (GPS) at 3 Months-individual Lower Extremity Joint Kinematics — 0.41; -0.48 units on a scale — p=0.36
N/A N=112 Efficacy of the WalkAide and AFOs for CVA
Stroke
Primary: Figure 8 Walking Speed Before and After Intervention. — .337; .312; .261; .432 meters/second
N/A N=9 Bracing for Walking in Parkinson's Disease
Gait Disorders, Neurologic · Parkinson Disease
Primary: Change in Gait Capacity as Assessed b 6-Minute Walk Test — 235.7; 150.0 Feet
Phase 2 N=39 Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
Posterior Tibial Tendon Dysfunction
Primary: Foot Function Index(FFI) — 16.0; 12.7; 8.1; 8.3 units on a scale
N/A N=495 WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients
Stroke
Primary: Gait Velocity — .682; .635 m/sec
N/A N=33 Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis
Peripheral Artery Disease
Primary: Maximum Walking Time From the Gardner Graded Treadmill Protocol — 117.7; 197.5; 188; 339.9 Seconds
N/A N=6 iStride(TM) Device Used for Stroke Rehabilitation
Stroke
Primary: Percentage Change in Step Length Asymmetry — 11.6 % change in asymmetry
N/A N=70 Evaluation of Dual Channel vs. Single Channel FES for Dropfoot
Dropfoot
Primary: Ankle Movement as Good as or Better With the Segmented Electrode as With the QFE — 3.63 units on a scale
N/A N=6 Gait in Children With Down Syndrome While Wearing Orthoses
Down Syndrome
Primary: Step Width — 10.4 cm
N/A N=26 Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors
Stroke · Hemiparesis · Lower Extremity Paresis
Primary: Change in Lower Extremity Fugl-Meyer Score at End of Treatment — 0.93; 1.8 units on a scale
Phase 3 N=120 Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity
Post-Stroke Spasticity · Cerebrovascular Accident
Primary: Area Under the Curve (AUC) for the Change From Baseline in Modified Ashworth Scale (MAS) Ankle Score to the End of the DB Phase (Week 12) — -8.513; -5.085 Score*week…
N/A N=23 Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation
Stroke
Primary: Change in Ten Minute Walk Test (10MWT) — 0.551 meters per second (m/s) — p=.0001
N/A N=13 Assessment of the Effect of Botulinum Toxin in Extensor Digitorum Brevis Via Strain Gauge and Nerve Conduction Studies
Muscle Strength · Botulinum Toxins, Type A
Primary: Change in Measured Force (Change From Baseline) (Using Strain Gauges) of Dorsiflexion of Digits 2 and 3 ("Force of EDB") After vs. Before Botulinum Toxin Injection Into…
N/A N=5 Clinical Study to Evaluate the Implantation of the ActiGait Drop Foot Stimulator System
Stroke · Hemiplegia
Primary: Distance Walked in 6 Minutes — 211; 211; 260; 214 m
Early Phase 1 N=7 Operant H-reflex Down-conditioning of Rectus Femoris in Post-stroke Stiff Knee Gait
Training
Primary: Percentage Change From Baseline in RF H-reflex Magnitude — -43.82 percentage change in reflex size
N/A N=11 Orthotics in Ambulatory Cerebral Palsy
Cerebral Palsy
Primary: Walking Activity Levels — 4660; 4897 average total strides/day — p=< 0.05
N/A N=10 Effects of an Overground Propulsion Neuroprosthesis in Community-dwelling Individuals After Stroke
Stroke
Primary: Immediate Change in Walking Speed — 0.01; 0.03 meters per second (m/s)
Phase 3 N=216 Dysport® Pediatric Lower Limb Spasticity Follow-on Study
Cerebral Palsy · Muscle Spasticity · Children
Primary: Number of Subjects With Treatment Emergent Adverse Events (TEAEs) Reported in the Double Blind (DB) + Open Label (OL) Period. — 177; 5; 91; 151 participants
Early Phase 1 N=44 Sensory Augmentation Methods in Stroke
Stroke
Primary: Percentage of Participants With Related or Serious Adverse Events — 1; 0 Participants — p=1
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale
N/A N=5 Comparison of the Functional Walking Outcomes of Two Settings of a Commercially Available AFO in Adult Stroke Patients
Walking Aided by a Leg Brace in Stroke Subjects
Primary: Self-selected Walking Velocity — 0.71; 0.74 m/s