N/A N=3,013 Implementation of Practice Standards for ECG Monitoring
Cardiovascular Disease
Primary: Nurses' Knowledge and Skills Related to ECG Monitoring — 49.2; 47.2; 70.2; 49.4 percentage of items correctly answered
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=22 Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects
Drug-induced Surface ECG Changes
Primary: Placebo, and Baseline-adjusted Changes in PR, QRS, J-Tpeak, Tpeak-Tend and QTc — 6.5; 2.3; 32.1; 5.1 ms — p=<0.05
N/A N=20 ECG Belt to Assess Electrical Synchronization
Bradycardia · Heart Failure
Primary: • ECG Belt Analysis of Standard Deviation of Activation Times (SDAT) of LBBP Compared to Native Conduction — 38.6; 20.5 ms
N/A N=36 Single Center Pilot Study Using the ECGenius System to Collect Electrogram Data to Test an Ablation Impact Algorithm
Persistent Atrial Fibrillation · Cardiac Arrhythmia
Primary: Ability to Collect CS Data — 34 Participants
Phase 3 N=794 Tele-Electrocardiography in Emergency Cardiac Care
Myocardial Infarction · Chest Pain
Primary: Hospital Time to Treatment for Patients With Unstable Angina/Non-STEMI — 23; 31 minutes
N/A N=408 ECG Belt for CRT Response
Heart Failure
Primary: Change in Left Ventricular End Systolic Volume (LVESV) From Baseline to 6 Months Post-implant. — -11.7; -14.7 Percent Change
N/A N=546 ECG App Algorithms Clinical Validation Study
Atrial Fibrillation
Primary: Percentage of Trials With Correct Classification of Normal Sinus Rhythm on Simultaneous 12-lead ECG as "Sinus Rhythm" or "High Heart Rate" on a Readable and Classifiable…
N/A N=602 Electrocardiogram Clinical Validation Study
Atrial Fibrillation
Primary: Number of Participants With Software's Rhythm Classification of SR in Agreement to a Physician's Interpretation of a Gold Standard 12-lead ECG — 238 Participants…
Early Phase 1 N=11 EEG Characteristics in ECT
Electroconvulsive Therapy · Direct Current Electroencephalogram · Ketamine
Primary: Number of Participants Assessed for Clinical Efficacy of ECT — 11 Participants
N/A N=21 The Automated Calculation of AF Cycle Length and Complexity Using a Novel EP Recording System
Atrial Fibrillation
Primary: Measurement of AF Cycle Length — 171.64 ms
N/A N=195 Leadless Electrocardiogram (ECG) Evaluation Study
Heart Failure
Primary: Proportion of Patients With LECG Performing Clinically Equivalent to PECG During Standard Pacemaker Follow-up Procedure. — 0.99; 0.98; 0.98; 0.96 proportion
N/A N=3,000 Diagnostic Accuracy of Electrocardiogram for Acute Coronary Occlusion Resulting in Myocardial Infarction
Myocardial Infarction · Acute Coronary Syndrome · Coronary Artery Disease
Primary: The Sensitivity and Specificity of ECG for Acute Coronary Occlusion. — 767; 282; 16 Participants
N/A N=300 Electrophysiological Effects of Late PCI After MI
Cardiovascular Diseases · Heart Diseases · Myocardial Infarction
Primary: Short-termed Fractal Scaling Exponent (Alpha 1) — 0.01; -0.03 unit-less — p=0.34
Phase 1 N=22 Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block
Drug-induced QT Prolongation · Pharmacokinetics · Pharmacodynamics
Primary: Change in Placebo Corrected Change From Baseline QTc and J-Tpeakc Intervals on the ECG Measured in Milliseconds When Dofetilide is Administered With Mexiletine or…
N/A N=314 Evaluation of Synthesized 18-Lead ECG in the Emergency Department
Chest Pain
Primary: Sensitivity and Specificity Agreement Between Synthesized and Actual 18-lead ECGs in the Identification of ST Elevation, ST Depression, and T Wave Inversion — 100; 100…
Phase 2 N=55 Cardiac Electrophysiological Study
Atrial Flutter
Primary: LAERP (Left Atrial Effective Refractory Period (ie, the Longest S1-S2 Interval That Fails to Result in Atrial Depolarisation)) — 11; 43; 55; 50 ms
N/A N=27 An Evaluation of the Safety and Performance of the CathVision ECGenius® System.
Cardiac Arrhythmia
Primary: Baseline Noise Comparison — 19; 46; 31; 463 μV
N/A N=47 The Effects of Menstrual Cycle Phase on Exercise Treadmill Test Results in Premenopausal Women
Menstrual Cycle · Exercise Treadmill
Primary: ST/HR Index (μV/Bpm) — 1.2; 1.3 μV/Bpm — p=0.521
Phase 1 N=47 This Study in Healthy Men and Women Tests Whether BI 409306 Has an Effect on the ECG (Thorough QT Study)
Healthy
Primary: Change From Baseline in QTcF at That Timepoint Between 20 Minutes to 24 Hours After Drug Administration Where the Difference of Means in QTcF Changes From Baseline…
Phase 1 N=60 CiPA Phase 1 ECG Biomarker Validation Study
Drug-induced QT Prolongation · Pharmacokinetics · Pharmacodynamics
Primary: Change From Baseline J-Tpeakc With "Balanced Ion Channel" Drugs (Ranolazine, Verapamil, Lopinavir / Ritonavir) — -8.3; -7.8; -11.5; -10.9 ms
N/A N=27 Vascular Positioning System G4 Algorithm ECG Data Collection for Model Training Study
Peripheral ICC
Primary: VPS G4 System Digital Data vs GE MAC 5500 Ecg Machine Data — 20 subjects who digital data was captured
N/A N=20 Clinical Comparison of Electrocardiograms Collected Using an Ambulatory Holter
Electrocardiography
Primary: Arrythmia — 4.6; 7.95 Quality rating
Phase 1 N=32 Food and Insulin Effect on QT/QTC Interval of ECG
Effects of Different Meals on the QT/QTc Interval · Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use · C-Peptide Effects on the QT/QTc Interval
Primary: The Effect of Food (Fasted and Fed State) on the Degree of QT Prolongation Caused by Moxifloxacin — 14.4; 11.6 ms — p=0.05
N/A N=20 EGM Analysis in Idiopathic Outflow Tract Ventricular Arrhythmia
Ventricular Outflow Tract Tachycardia
Primary: Percent of Ablation Targets With Termination of the Clinical Ventricular Arrhythmia After RF Energy Delivery — 20 Participants
N/A N=60 Evaluation of Electrocardiographic Guidance in Accurate Peripherally Inserted Central Catheter Placement in Children.
Venous Insufficiency
Primary: Number of Participants With Successful Placement of Peripherally Inserted Central Catheter (PICC) — 40; 14; 8; 18 Participants
Phase 1 N=7 A Study on the Effects of LY2409021 on the Electrical Impulses of the Heart
Diabetes Mellitus, Type 2
Primary: Part B: Mean Change From Baseline in 12-lead Electrocardiogram (ECG) Corrected QT Intervals (LY2409021) — -14.72; -15.35; -5.43; -9.12 milliseconds
Phase 3 N=261 Impedance Cardiography: Clinical Evaluation of Endotracheal Cardiac Output Monitor (ECOM)
Cardiac Output
Primary: Comparison of ECOM Impedance and Thermodilution Cardiac Output Measurements — 0.31 liters/min
N/A N=13 Effect of Chronic Changes in Heart Rate on Congestive Heart Failure
Heart Failure, Congestive
Primary: Ejection Fraction — 33; 30; 25 % of blood ejected with each beat
N/A N=242 The IPED (Investigation of Palpitations in the ED) Study
Presyncope · Arrhythmias, Cardiac · Tachycardia, Supraventricular
Primary: Number of Participants With Symptomatic Rhythm Detection up to 90 Days — 69; 11 Participants
N/A N=22 Endothelial Function and Cardiac Output in RV Pacing
Bradycardia
Primary: Endothelial Function Assessed by Flow Mediated Vasodilatation — 1.96; 1.73 EndoPAT index (EnFI)