Phase 4 N=100 Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Foot and Ankle Surgeries · Bunion
Primary: Total Estimated Blood Loss — 40.41; 18.75 ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=80 Saphenous Nerve Block for Foot and Ankle Surgery
Saphenous Nerve Block
Primary: Block Success — 18; 22 participants — p=0.25
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
N/A N=273 Treatment Outcomes for Ankle Arthritis
Osteoarthritis
Primary: Musculoskeletal Functional Assessment (MFA) — -12.5; -15.0 units on a scale
Phase 4 N=20 MIDCAB (Mid-Calf Block) for Foot Surgery
Ankle Surgery · Foot Surgery
Primary: Block Duration — 18.2 hours
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
Phase 4 N=36 Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.
Nerve Block · General Anesthesia · Spinal Anesthesia
Primary: Time Until Patient is Ready for Discharge From Post-Anesthesia Care Unit (PACU) to Home. — 81; 43.5 Minutes
Phase 4 N=50 Continuous Wound Infiltration After Hallux Valgus Surgery
Hallux Valgus
Primary: Average Postoperative Numeric Rating Scale (NRS) for Pain — 2.0; 1.9 units on a scale — p=0.596
N/A N=75 Excess Opioid Disposal Following Orthopedic Foot and Ankle Surgery
Medication Disposal · Behavior
Primary: Number of Participants Who Safely Disposed The Excess Medication — 8; 22 Participants
N/A N=242 Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Postoperative Infection · Postoperative Complications
Primary: Bacterial Culture Growth — 32; 33 Participants
N/A N=124 Ambispective, Multicentre, Open-label Study Evaluating the Clinical Outcomes of Foot Surgery Using SERF Medical Devices
Foot Diseases
Primary: Reduction of the Patient's Pain and Restoration of Walking — 42.46; 88.44 points
N/A N=233 A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
Ankle Injuries
Primary: Percentage of Nonpalpable Hardware — 71; 55; 64; 66 percentage of participants
N/A N=21 Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Syndesmotic Injuries · Ligament Rupture · Bimalleolar Fractures
Primary: Syndesmotic Volumetric Ratio — 1.2; 1.1 Volumetric Ratio
Phase 4 N=36 Foot and Ankle Clinic Application for Liposomal Related Anesthetic
Ankle Arthrodesis · Hindfoot Arthrodesis · Tibitalocalceal Arthrodesis
Primary: Amount of Narcotic Use — 236.68 mg
N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
N/A N=98 Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement
Ankle Osteoarthritis
Primary: Pain Following a Total Ankle Replacement as Measured by the Visual Analog Scale (VAS) for Pain — 67.0; 71.3; 16.7; 18.6 mm — p=0.29
N/A N=64 Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.
Hallux Limitus of Left Great Toe · Rheumatoid Arthritis · Arthritis of 1st Metatarsophalangeal Joint
Primary: AOFAS Hallux-MTP-IP Score - Overall — 88.9 units on a scale
Phase 4 N=14 Anesthesia for Pain After Ankle Fracture Surgery
Chronic Pain · Ankle Fracture Surgery · Regional Anesthesia
Primary: Pain Score at 12 Months - Experimental Group vs. Control Group — 36.33; 44.00 units on a scale — p=0.1269
N/A N=111 Brace Versus Casting in Pediatric Low Risk Ankle Fractures
Ankle Fracture
Primary: Functional Outcome as Measured by the Activities Scale for Kids at 4 Weeks From the Time of the Initial Injury — 85.3; 91.3 percentage of questions
Phase 3 N=30 Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Articular Cartilage Defects of Ankle Joint
Primary: Average Change From Baseline in American Orthopedic Foot and Ankle Society(AOFAS) at 12 Months Post-surgery — 16.93 scores
N/A N=11 Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients
Ankle Osteoarthritis · Healthy Ankles
Primary: Daily Step Count (# Steps) — 3453; 2399; 3453; 2745 steps
N/A N=50 Ankle Foot Orthosis Comparative Effect
Foot Injuries and Disorders
Primary: PROMIS Patient Reported Outcomes for Physical Function — 44.78; 45.02 score on a scale
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale
N/A N=30 Patient Specific 3D Printed Diabetic Insoles to Reduce Plantar Pressure
Diabetes
Primary: Plantar Pressure - Standard of Care — 202.71 kPa
Phase 2 N=35 Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)
Chronic Exertional Compartment Syndrome
Primary: University of Wisconsin Running Injury and Recovery Index Score at Baseline — 10.86; 11.86; 12.14; 9.75 cumulative score on a 9-item scale
N/A N=53 Timing of Weight Bearing After Hallux Valgus Surgery
Hallux Valgus and Bunion
Primary: Hallux Valgus Angle as a Measure of the Radiological Changes — 35.6; 37.4; 8.8; 7.2 degrees
N/A N=22 Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Ankle Fractures · Post-traumatic Osteoarthritis · Osteoarthritis Ankle
Primary: Joint Contact Stress Time Exposure (Model Estimated) — 4.44; 3.97; 4.08; 4.25 MPa-s/gait cycle
N/A N=23 Weightbearing Assessment of Tarsal Instability
Adult-acquired Flatfoot Disorder (AAFD)
Primary: Change in Joint Motion Between Touch-down Bearing Navicular and Full-weight Bearing Navicular — 3.56; 4.36; -0.1666; -0.170 mm
N/A N=33 Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis
Peripheral Artery Disease
Primary: Maximum Walking Time From the Gardner Graded Treadmill Protocol — 117.7; 197.5; 188; 339.9 Seconds