N/A N=196 Community Study of Outcome Monitoring for Emotional Disorders in Teens
Depression · Anxiety
Primary: Clinical Global Impression - Improvement (CGI-I) Scores — 2.85; 3.20; 3.02; 2.47 score on a scale — p=.338
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=58 Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders
Mood Disorder · Disruptive Behavior Disorders
Primary: Change in Affective Reactivity Index - Youth (ARI-Y) — -2.9; -0.8 score on a scale
N/A N=93 Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder
Borderline Personality Disorder · Emotional Problem
Primary: Maternal Emotion Dysregulation — 82.35; 91.8 score on a scale — p=.002
N/A N=28 Neurobehavioral Intervention as a Novel Treatment Approach for Emotion-Regulatory Deficits
Anxiety · Depression
Primary: Reaction Time to Facial Affect Identification During Emotional Conflict — 802.15; 889.14; 848.79; 937.97 milliseconds — p=0.004
N/A N=22 Treatment of Aggression, Anger and Emotional Dysregulation in Borderline Personality Disorder
Borderline Personality Disorder
Primary: Self-Report of Difficulties in Emotion Regulation (DERS) — 101.5; 54.8; 120.5; 56.6 units on a scale — p=<0.004
N/A N=17 The Emotion Builder: An Intervention for Emotional Deficits After Brain Injury
Traumatic Brain Injury · Alexithymia
Primary: Toronto Alexithymia Scale-20 (TAS-20) — 52.54 units on a scale
Phase 4 N=40 Depression, Epinephrine, and Platelet Function
Major Depressive Disorder
Primary: Response of Participants, Defined by Change in the 21-item Hamilton Depression Rating Scale (HDRS) From Baseline to Week8 — 5; 9; 2; 4 participants — p=.918
Phase 4 N=79 Evaluation of Emotional Disorders During Treatment by Interferon Beta in Relapsing-remitting Multiple Sclerosis Patients
Multiple Sclerosis, Relapsing, Remitting
Primary: Change From Baseline in Emotional Dyscontrol Sub-score of the Depressive Mood Scale (Echelle d'Humeur Depressive [EHD]) Scale at Month 12 — 12.7; -0.5 units on a scale
N/A N=60 Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)
Mood Disorders
Primary: Functional Magnetic Resonance Imaging (fMRI) Blood Oxygen-level Dependent (BOLD) Signal Changes in Left Amygdala at Baseline and at the End of the Intervention — 1.62…
Phase 4 N=54 Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
Non-verbal Learning Disorder · Autism Spectrum Disorder · Autism
Primary: Mean Change in the Parent-Young Mania Rating Scale (P-YMRS) Score — 0.0; -2.6 Units on a Scale
N/A N=45 Tantrum Tamers 2.0: The Role of Emotion
Child Behavior · Attention Deficit and Disruptive Behavior Disorders · Problem Behavior
Primary: Change in Eyberg Child Behavior Inventory (ECBI) Score-Intensity — -45.46 score on a scale
N/A N=40 Relationship Between Attention and Emotional Regulation Post-Traumatic Brain Injury (TBI)
Traumatic Brain Injury
Primary: Baseline Measures Before Treatment
N/A N=37 A Unified Treatment for Anxiety Disorders
Emotional Disorders · Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for DSM-IV — 5.23; 5.09; 3.18; 5.14 score on a scale
N/A N=15 Adolescent Attention to Emotion Study
Depression
Primary: Affect-biased Attention Following Neurofeedback (Immediately Post-Intervention) — .41 Proportion (0-1) — p=.004
N/A N=32 A One-Day ACT Workshop for Emotional Eating
Emotional Eating · Eating Behavior
Primary: Emotional Eating - 2-weeks Post-intervention — 3.27 units on a scale
Phase 4 N=40 Open-Label Study of N-Acetylcysteine in Children and Adolescents 5-17 With Bipolar Spectrum Disorders
Bipolar Disorder
Primary: Mean Change in the Young Mania Rating Scale (YMRS) Score — -8.1 score on a scale
N/A N=163 Effect of Emotion Mindsets on Emotion Processing
Emotions
Primary: Mean Change From Pre to Post Mindset Manipulation on Emotion Mindset Scale (Measures Beliefs About Whether Emotions Are Fixed or Malleable) — 3.03; 3.03; 2.17; 2.76…
N/A N=24 Using Emotion Regulation to Decrease Aggression in Veterans With PTSD
Chronic Post-Traumatic Stress Disorder
Primary: Overt Aggression Scale — 14.2 events
N/A N=229 A Randomized Controlled Trial of PCIT-ED for Preschool Depression
Depressive Disorder, Major
Primary: Kiddie Schedule for Affective Disorders and Schizophrenia - Early Childhood (KSADS-EC) MDD Core Symptom Score — 1.74; 4.15 number of symptoms (0-9)
Phase 2 N=138 Neural Substrates of Emotion: Impact of Cocaine Dependence
Cocaine Use Disorder
Primary: Functional Connectivity Between Corticolimbic Brain Regions During Acute Social Stress — .011; .012; .043; .0008 Arbitrary units
N/A N=28 Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children
Anxiety Disorder · Depressive Disorder
Primary: Post-Intervention Youth-reported Anxiety Disorder Symptoms From Pre- to Post-Intervention — .94 mean score on scale
N/A N=47 Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
Substance Use Disorders · Depression · Anxiety
Primary: Acceptability of Adding UP Group Intervention to TAU — 28.0 units on a scale
N/A N=16 Modulation of Emotion Perception in Humans Via Amygdala Stimulation
Refractory Epilepsy
Primary: Z-score Gamma Power in Amygdala Per Valence Category — 1.21; 1.88; 1.24 z-score
N/A N=20 Dialectical Behaviour Group Therapy for Adults With Intellectual Disabilities
Intellectual Disability
Primary: Change in Difficulties in Emotional Regulation Scale (Gratz & Roemner, 2004) — 1.4; 0.8 score on a scale
N/A N=1,206 Epidemiology of Depression, Anxiety, and Cognitive Impairment
Depression · Anxiety · Cognitive Impairment
Primary: Participants With Depression by Patient Health Questionnaire - 9 — 177 participants
Phase 4 N=27 A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth
Mood Disturbance · Mood Disorders · Natural Supplements
Primary: Mean Change in the Parent-Young Mania Rating Scale (P-YMRS) Score — -2.4; -1.9 Units on YMRS Scale
N/A N=52 Skills to Enhance Positive Affect in Suicidal Adolescents
Suicidal Ideation · Suicide, Attempted
Primary: Dot Probe Task — 1.56; -1.65; -1.48; 1.23 milliseconds — p=.034
N/A N=58 Sleep and Emotional Memory in Peripubertal Anxiety
Anxiety
Primary: Scores on the Lure Generalization Index (a Behavioral Measure of Generalization) — .24; .26; .14; .10 units on a scale — p=<.046
Phase 4 N=121 Emotional and Cognitive Control in Late-Onset Depression
Depression
Primary: Change in Depression Severity (Measured by Montgomery Asberg Depression Rating Scale) — 25.26; 1.03; 13.78; 1.08 score on a scale — p=< 0.025
N/A N=56 The Effects of Emotional Exposure on State Anxiety
Generalized Anxiety Disorder
Primary: STAI-Y1 Score Assessed at Baseline, Post-Condition and Post-Exposure — 33.48; 33.53; 27.43; 29.78 score on a scale — p=>.05