N/A N=330 PRIDE: Preventing Respiratory Illnesses During Childhood Study
Tobacco Smoke Pollution
Primary: Air Nicotine Levels — 1.17; 0.58; 0.71; 0.51 mg/m^3
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=484 Parent eReferral to Tobacco Quitline
Secondhand Smoke
Primary: Number of Parent Smokers Who Enrolled in Quitline — 209; 245; 24; 5 Participants
N/A N=64 Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
Tobacco Use
Primary: Number of Cigarettes Purchased — 154.7; 119.2 average number of cigarettes
N/A N=136 COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM
Substance-Related Disorders
Primary: High Ventilated Cigarette Purchases — 104.22; 29.64; 52.38; 47.41 single unit quantity purchased
N/A N=401 Real-Life Passive Exposure Assessment of IQOS
Environmental Exposure
Primary: NEQ: (Non-Exposure Event) — 0.03845; 4.159; 5.695; 0.06876 mg/g
N/A N=765 An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients
Smoking Cessation
Primary: Percentage of Participants With Self-reported Prolonged Abstinence at 6 Weeks — 4.2; 4.2 percentage of participants
N/A N=165 NICU Asthma Education and Secondhand Smoke Reduction Study
Respiratory Illness
Primary: Infants Living in Smoke-free Environments. — 65; 64 participants
N/A N=160 Reduced Exposure Study in Smokers Using THS 2.2 With 5 Days in a Confinement Setting.
Smoking
Primary: Concentration of Monohydroxybutenyl Mercapturic Acid (MHBMA) — 194.05; 2314.37; 168.01 pg/mg creat — p=<0.001
N/A N=160 Reduced Exposure Study in Smokers Using the Tobacco Heating System 2.2 (THS 2.2) for 5 Days in a Confinement Setting
Smoking
Primary: Concentration of Monohydroxybutenyl Mercapturic Acid (MHBMA) — 106.25; 460.15; 91.73 pg/mg creat — p=<0.001
N/A N=160 Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Smoking
Primary: Concentration of Monohydroxybutenylmercapturic Acid (MHBMA) — 110.96; 882.25; 94.97 pg/mg creat — p=<0.001
N/A N=6,011 European Regulatory Science on Tobacco: Policy Implementation to Reduce Lung Diseases (EUREST-PLUS)
Tobacco Dependence
Primary: Number of Participants Who Think About the Harm of Smoking — 67; 272; 192; 194 Participants
Phase 4 N=32 Nicotine Patch as an Adjunctive Intervention to Reduce Secondhand Smoke Among NICU Families
Environmental Tobacco Smoke · Smoking Cessation
Primary: Feasibility as Assessed by Number of Participants Who Accepted NRT Patches From Research Staff. — 13 Participants
N/A N=164 Telehealth-Filter Ventilation ( COMET2P1 )
Tobacco Use
Primary: Change in Total NNAL: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol [ng/g Creatinine] — 0.97; 1.05 ng/g creatinine
N/A N=60 Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
COPD · Asthma · Second Hand Tobacco Smoke
Primary: Respiratory Rate — 21.66; 21.57 BR/M breathing rate per min
N/A N=972 Cessation of Smoking Trial in the Emergency Department
Smoking Cessation · Electronic Cigarette Use · E-Cig Use
Primary: Continuous Smoking Abstinence — 35; 20 Participants
N/A N=974 Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking
Inflammation · Oxidative Stress · Smoking
Primary: Carboxyhemoglobin (COHb) in Blood — 3.07; 1.52; 1.49 % of CO saturated hemoglobin — p=<0.001
N/A N=396 Babies Living Safe and Smokefree
Second Hand Tobacco Smoke · Nicotine Dependence
Primary: Child Urine Cotinine — 1.00; .97; 1.09; 1.00 log transformed ng/mL
N/A N=91 Reduced Exposure to HPHC in Smokers Switching From Cigarettes to Different Versions of THS
Smoking · Tobacco Smoking · Tobacco Use
Primary: Concentration of 3-hydroxypropylmercapturic Acid (3-HPMA) — 786.07; 674.08; 781.63; 765.28 ng/mg creatinine
N/A N=296 Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products
Tobacco Use
Primary: Total 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) — 170.800; 174.464; 194.995; 228.143 pg/mg creatinine — p=<.0001
N/A N=160 Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting
Smoking
Primary: Concentration of Monohydroxybutenyl Mercapturic Acid (MHBMA) — 83.21; 617.04; 83.57 pg/mg creat — p=<.001
N/A N=220 Heated Tobacco Products vs Electronic Cigarettes
Smoking, Cigarette
Primary: Number of Participants With Smoking Cessation — 60; 44 Participants — p=0.0051
N/A N=52 Menthol and Mint Experimental Tobacco Marketplace (ETM) Study
Cigarette Smoking · Vaping
Primary: Total Amount of Combusted Tobacco Purchased — 990.6 mg
N/A N=11,902 The TackSHS Survey: a Pan-European Study on SHS
Second Hand Tobacco Smoke
Primary: Prevalence of Daily Exposure to Secondhand Smoke (SHS) in Indoor Settings — 2888 Participants
N/A N=80 Reduced Exposure Study Using CHTP 1.0 During 5 Days in Confinement.
Smoking
Primary: Concentration of Monohydroxybutenyl Mercapturic Acid (MHBMA) — 327.08; 1903.61 pg/mg creat — p=<.001
N/A N=25 Effects of Cigarette and E-cigarette Flavors on Substitutability in the ETM
Cigarette Smoking Behavior
Primary: Nicotine/Tobacco Products Substitution — 1326.25; 206; 120.83; 46.79 mg of nicotine purchased
N/A N=36 Palatability of Experimental Cigarettes - Study 2
Smoking
Primary: Change in UrineTotal Nicotine Equivalent (TNE) Between Baseline and Week 1 — -16.2; -7.6; 1.3 nmols/ml
N/A N=1,044 Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers
Tobacco Use Cessation · Smoking Cessation · Smoking
Primary: Number of Participants With Exhaled Carbon Monoxide Confirmed Abstinence — 53; 65 participants
N/A N=817 eCEASE to Support Treatment for Parental Tobacco Use
Tobacco Smoking · Second Hand Tobacco Smoke · Smoking Cessation
Primary: Parental Combusted Tobacco Quit Rate at 12 Months — 34; 26 Participants
Phase 3 N=136 Smoking Termination Enhancement Project (STEP)
Smoking
Primary: Percentage of Participants Who Abstained From Smoking at 10 and 30 Weeks Post Quit Day — 5; 9; 4; 9 number of participants
Early Phase 1 N=11 Ventilation and Pulmonary Endothelium Toxicities of E-cigarettes: A Randomized Crossover Pilot Study
Pulmonary Disease, Chronic Obstructive · E-cigarettes
Primary: Pulmonary Microvascular Blood Flow (PMBF), Measured on Gadolinium-enhanced MRI, Between E-cigarette Exposed and Unexposed Conditions — 74.4; 63.1 mL(blood)/min/mL(lung)…