N/A N=20 A Novel Method for Capturing the Visual Evoked Potential During Spine Surgery Under Total Intravenous Anesthesia
Evoked Potentials, Visual
Primary: Number of Participants With Presence of VEPs — 18 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Safety and Efficacy of Using SightSaver Visual Evoked Potential (VEP) for VEP Monitoring in Prone Spine Surgery
Ischemic Optic Neuropathy
Primary: Efficacy in Detecting Subtle Intraoperative VEP Changes Using SightSaver Visual Stimulator During Spine Prone Surgeries Under Balanced General Anesthesia Versus TIVA…
N/A N=51 Normative Database for Pattern Electroretinogram (PERG) and Flash Electroretinogram (FERG)
Glaucoma
Primary: Flash Electroretinogram (FERG) Module Using Diopsys NOVA (Neuro Optic Vision Assessment) Amplitude — -1.68 micro volts
N/A N=136 How Accurately Does the Diopsys Visual Evoked Potential (VEP) Vision Testing System Detect Glaucoma?
Glaucoma Diagnosis
Primary: Visual Evoked Potential (VEP) — 6.7; 7.1; 4.1 microvolts (uV) (amplitude)
N/A N=22 Trial of Alternating Current Stimulation in Optic Neuropathy
Optic Nerve Diseases · Optic Nerve Injuries · Optic Neuropathies
Primary: Detection Accuracy (DA) Change in Percent Over Baseline Within Defective Visual Field Sectors — 24.75; 39.16 percent change
N/A N=6 Feasibility Electrical Stimulation Study for Visual Hallucinations
Schizophrenia · Schizoaffective Disorder · Bipolar Disorder
Primary: Steady State Visual Evoked Potential (ssVEP) — 1.725; 1.160; 1.180; 1.005 microvolts — p=0.10
N/A N=12 Multimodal Analysis and Electroretinogram in VKH From Acute Onset - Part I
Uveomeningoencephalitic Syndrome · Inflammation · Choroid Disease
Primary: Median Values of ERG Scotopic Parameters at 12-month — 201; 210; 508; 92 microvolts — p=<0.001
N/A N=6 The Perceptual Experience of Argus II Users
Retinitis Pigmentosa
Primary: Number of Phosphenes Perceived — 1.09; 1.43; 1.46; 1.41 number of phosphenes — p=0.002
Phase 4 N=13 Effect of Valproic Acid Concentration on Photic Response
Photosensitive Epilepsy
Primary: Difference in SPR During Placebo and VPA Infusions — 15.917; 14.609 standard photosensitive range (SPR) — p=0.016
N/A N=42 Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study
Chronic Pain
Primary: The Proportion of Subjects With a Reduction in Overstimulation Sensation With SCS Using a Closed-loop Algorithm Compared With SCS in Open-loop — 41 Participants — p=<0.001
N/A N=63 Transcorneal Electrostimulation for Therapy of Retinitis Pigmentosa
Retinitis Pigmentosa
Primary: Visual Field, III4e — 4835.29; 4988.43; 6234.59; 4488.39 deg2
N/A N=48 Visual Restoration for Hemianopia
Stroke Induced Vision Loss · Hemianopia · Quadrantanopia
Primary: 24-2 Humphrey PMD Change From Baseline to 6-month Post-training Timepoint — 0.84; 0.10; 0.58; 0.12 decibels
N/A N=75 Visual Stimulation for Pain Relief
Pain
Primary: Visual Analog Scale (VAS) Score — 24.77; 25.02; 25.19; 23.64 score on a scale — p=.37
Phase 4 N=12 Effects of Perampanel on Neurophysiology Test Perimeters
Healthy
Primary: Change in Baseline Visual Evoked Potential (P100) Amplitude
N/A N=97 Electric Stimulation of the Eye to Improve Vision After Trauma
Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) · Trauma · Multiple Sclerosis (MS)
Primary: Evaluation of the Effectiveness and Safety of Transcorneal Electrical Stimulation to Improve Visual Acuity — -0.23; -0.14; -0.08; -0.06 logMAR
Phase 4 N=54 Comparison of Visual Field Assessments Between Three Perimeters
Glaucoma
Primary: Total Acquisition Time (Both Eyes) — 4.44; 7.34; 7.71 minutes
N/A N=115 Heidelberg Edge Perimetry (HEP) Detecting Glaucomatous Visual Field Defects
Glaucoma
Primary: Correlation Coefficient Between HEP and OVF Mean Deviation (MD) — -.86; -.37 Pearson's correlation coefficient
N/A N=20 Intracochlear Potentials: Volta Study
Hearing Loss
Primary: Normative Voltage Tomography Data — 19; 1; 19; 1 Participants
N/A N=180 Variability in Perimetry Study
Glaucoma
Primary: Number of Subjects Progressing in Each Group Using Pointwise Linear Regression — 0; 0 participants — p=.21
Phase 4 N=65 A Study of the Structure and Function of the Retina in Adult Patients With Refractory Complex Partial Seizures Treated With Vigabatrin (Sabril®)
Adult Refractory Complex Partial Seizures
Primary: Mean Change From Reference Value in Field Width as Measured by 30-2 SITA Fast in Field Sensitivity (Mean Deviation - MD in dB) — -0.28; -0.24; -0.14; -0.13 dB
Phase 2 N=52 Long-Term Assessment of Remyelinating Therapy
Acute Optic Neuritis
Primary: FF-VEP Latency of the Affected Eye as Compared to the Baseline of the Fellow Eye at 2 Years (+ up to 12 Months) After the Last Study Visit Assessment (Week 32) in RENEW…
N/A N=21 Visual Activity Evoked by Infrared in Humans After Dark Adaptation
Age Related Macular Degeneration · Retinitis Pigmentosa · Congenital Stationary Night Blindness
Primary: Visual Perception to Infrared: Mean Minimal Intensity (uW) at Which Participants Could See IR Between 900 - 1400 nm. — 0.671770454; 0.809204; 0.205456012; 0.222247 uW…
N/A N=79 Patient Perception of Visual Distortions
Cataract · Astigmatism
Primary: Visual Distortion Symptoms — 0.89; 0.38; 0.64; 0.38 rating of visual distortion symptoms
N/A N=44 Novel Portable Diagnostic Device for Automatic Detection of Relative Afferent Pupillary Defect
Multiple Sclerosis · Glaucoma
Primary: Number of Participants With Detected Relative Afferent Pupillary Defect (RAPD) — 44; 37 participants
Phase 2 N=90 Trial of Oral Valproic Acid for Retinitis Pigmentosa
Retinitis Pigmentosa
Primary: Mean Change in Visual Field Area From Baseline to 52 Weeks--III4e Isopter — -122.9; -112.0; -293.7; -237.1 Visual field area (degrees squared) — p=0.035
N/A N=25 Metabolic Changes in the Activated Human Visual Cortex During Mild Hypoxia
Brain Hypoxia
Primary: Change in Glutamate Concentration During a Visual Stimulus Measured by fMRS at Normoxia — 4 percentage of concentration (micromol/g)
N/A N=468 RETeval Study for Diabetic Retinopathy
Diabetic Retinopathy
Primary: Per Patient Referral Accuracy — 318 Participants
N/A N=26 Environmental Localization Mapping and Guidance for Visual Prosthesis Users
Retinitis Pigmentosa · Visual Impairment · Visual Prosthesis
Primary: Duration of Time to Complete Navigational Tasks as Assessed by the Mean Duration of Travel in Seconds Normalized by the Nominal Path Distance in Meters — 14.54; 14.09…
N/A N=72 visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated Perimetry
Glaucoma, Open-Angle
Primary: Mean Retinal Sensitivity From Two Machines — 29.9; 24.8; 28.7; 22.9 decibels
N/A N=37 Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness
Stroke · Neurologic Disorder · Traumatic Brain Injury
Primary: Bells Test — 14.2; 18.3; 19.3; 27.1 Number of items correct — p=0.1779